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Jake Nunn

Director at Zenas BioPharma
Board

About Jake Nunn

Independent director (since May 2024) and Chair of the Nominating & Corporate Governance Committee at Zenas BioPharma (ZBIO); age 54 as of April 28, 2025 . Nunn is a Partner at SR One Capital Management, LP (joined October 2022; became Partner June 2024) with prior roles as partner/venture advisor at NEA, partner/analyst at MPM BioEquities Fund, healthcare research analyst/portfolio manager at Franklin Templeton, and investment banker at Alex. Brown & Sons . He holds an A.B. in economics (Dartmouth), an M.B.A. (Stanford GSB), and is a CFA charterholder (member, CFA Society of San Francisco) .

Past Roles

OrganizationRoleTenureCommittees / Impact
SR One Capital Management, LPPartner (joined Oct 2022; Partner Jun 2024)2022–presentInvestor-director perspective; affiliated with a >5% holder in ZBIO
New Enterprise Associates (NEA)Venture advisor; Partner (Jun 2006–Jan 2019)2006–2019 (partner)Long-tenured biotech investor/operator
MPM BioEquities Fund (MPM Capital)Partner and analyst2001–2006Public markets/life sciences investing
Franklin Templeton InvestmentsHealthcare research analyst and portfolio managerNot disclosedBuy-side analysis/PM experience
Alex. Brown & SonsInvestment bankerNot disclosedCapital markets/M&A experience

External Roles

OrganizationRoleTenureNotes
Addex Therapeutics Ltd. (Nasdaq: ADXN)DirectorSince Jun 2018Current public company directorship
Regulus Therapeutics Inc. (Nasdaq: RGLS)DirectorSince Jun 2019Current public company directorship
SR One Capital Management, LPPartnerSince Jun 2024 (joined Oct 2022)Affiliated with 11.7% ZBIO holder via SR One entities

Board Governance

  • Committee assignments: Chair, Nominating & Corporate Governance Committee; not listed on Audit or Compensation .
  • Independence: Board determined all directors other than the CEO are independent under Nasdaq and SEC rules; applies to Nunn .
  • Attendance and engagement: Board met six times in 2024; each director attended at least 75% of board/committee meetings while serving. Nominating & Corporate Governance Committee was established at IPO and did not meet in 2024 .
  • Risk oversight remit: Nominating & Corporate Governance Committee oversees board independence and potential conflicts; Audit and Compensation oversee financial/cyber and compensation risk, respectively .

Fixed Compensation

Item2024 AmountNotes
Fees Earned or Paid in Cash ($) – Jake Nunn14,000Reflects partial-year service and role; see director compensation table
Non-employee Director Cash Policy (effective Sept 2024)Board retainer: 40,000; Nominating Chair: 8,000; Nominating member: 4,000Policy adopted at IPO
Non-employee Director Cash Policy (effective Jan 1, 2025)Board retainer: 40,000; Nominating Chair: 10,000; Nominating member: 5,000Retainers increased for 2025

Performance Compensation

Award DetailGrant DateTypeShares/OptionsExercise PriceVestingGrant Date Fair Value ($)
Annual/Initial Director Grant (IPO-related)Sep 2024Stock Options37,000$17.00Annual vesting over 3 years (service-based)479,668
Options Outstanding at 12/31/24 (Jake Nunn)n/aStock Options37,000n/aService-based; unexercisedn/a

Notes:

  • Director equity awards are time-based; no disclosed performance metrics (no PSUs/TSR frameworks for directors). Options granted under the 2024 Plan; exercise price at grant-date close .
  • Director compensation is subject to annual cap: $750,000 (or $1,000,000 for lead independent director/first year) .

Other Directorships & Interlocks

CompanyTypeRoleInterlock / Holder Exposure
Addex Therapeutics (ADXN)Public biotechDirectorNone disclosed with ZBIO
Regulus Therapeutics (RGLS)Public biotechDirectorNone disclosed with ZBIO
SR One-related fundsInvestorPartner at SR OneSR One entities collectively held 11.7% of ZBIO as of Apr 14, 2025
Director Affiliations MatrixGovernanceZBIO lists Nunn as affiliated with SR One Capital Management, LP

Expertise & Qualifications

  • Finance and life sciences investing expertise; board experience across multiple biotech companies .
  • Education: A.B. Economics (Dartmouth), M.B.A. (Stanford GSB); CFA charterholder .
  • Governance role: Chairs Nominating & Corporate Governance (board composition, succession, conflicts oversight) .

Equity Ownership

As-of DateBeneficial Ownership (Shares)% OutstandingNotes
Apr 14, 2025 (record date)<1%No shares reported beneficially owned; options not exercisable within 60 days
Options outstanding (12/31/24)37,000n/aOutstanding director options (service-based vesting)

Insider Trades (Form 4)

DateTransactionSharesPriceOwnership FormNotes
Oct 9, 2025Purchase (via Securities Purchase Agreement dated Oct 7, 2025)63,158$19.00IndirectHeld by SR One Capital Opportunities Fund I, LP; reporting person is Partner at SR One and LP in SR One Capital Opportunities Partners I, LP; disclaims beneficial ownership except to pecuniary interest. Separate indirect line shows 1,946,564 shares held by another SR One fund. Post-trade indirect holdings include 1,173,395 shares line item

Related-Party Exposure and Conflicts

  • Major holder affiliation: SR One entities held 4,911,539 ZBIO shares (11.7%) as of Apr 14, 2025; Nunn is a Partner at SR One. Board determined directors (excluding CEO) are independent under Nasdaq; Nominating Committee oversees conflicts .
  • Pre-IPO investors’ rights: Fourth Amended and Restated Shareholders Agreement provided board seats pre-IPO and registration rights (demand/S-3/piggyback) that persist per terms; Nunn among directors previously elected under this agreement .
  • Financing with affiliated holders: In May 2024 Series C financing, entities affiliated with SR One purchased 23,238,113 preferred shares (~$40.0M); ZBIO discloses this as a related party context with multiple board-affiliated investors .

Policy Controls and Practices

  • Anti-hedging: Directors/officers prohibited from hedging or monetization transactions; designed to align with shareholder risk .
  • Clawback: Nasdaq-compliant incentive compensation clawback policy adopted (Rule 10D-1) .
  • Related party review: Audit Committee must review/approve related person transactions; formal written policy adopted .

Director Compensation (Context and Structure)

Element2024 – NunnStructure / Terms
Cash (retainers/fees)$14,000Per policy; board/committee retainers; partial-year service
Equity (options grant-date FV)$479,66837,000 options @ $17.00; annual vesting over 3 years (service-based)

Governance Assessment

  • Strengths: Independent director; deep capital markets and biotech investing background; chairs Nominating & Corporate Governance (succession/composition/conflict oversight); anti-hedging and clawback policies in place .
  • Alignment: Director pay is largely equity-based (time-vested options). Insider purchase (indirect via SR One fund) in Oct 2025 adds positive signal of investor alignment, though held through affiliated fund and disclaimed beyond pecuniary interest .
  • Considerations: Investor–director interlocks are prominent (SR One 11.7%; Enavate 9.0%; Longitude 6.0%); Nunn’s SR One affiliation is a potential conflict area if matters involve SR One, mitigated by independence determinations and committee oversight policies .

RED FLAGS

  • Class action litigation: A securities complaint filed in U.S. District Court (Massachusetts) following the IPO names directors including Nunn; allegations include offering disclosure adequacy (status: allegations, not adjudicated) .
  • Board/committee cadence: Nominating & Corporate Governance Committee did not meet in 2024 given late formation at IPO—watch for 2025 activity and refresh practices .

Overall, Nunn brings financial acumen and network connectivity valuable for a newly public biotech, but his SR One affiliation alongside significant holder representation warrants continued monitoring of related-party safeguards, recusals, and transparent committee oversight .