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Ikarian Capital, LLC

CIK:0001778253
Hedge Fund
$811M AUM
133 holdings
Dallas, TX, United States
Founded:2015
5 employees
Latest filing:Jun 30, 2025

Ikarian Capital, LLC is a hedge fund and SEC-registered investment adviser based in Dallas, Texas. Founded in 2015 by Neil Shahrestani, Chart Westcott, and Vikram Khanna, it focuses on investment strategies in public equities with a particular strength in the healthcare and biotechnology sectors. The firm manages assets for a limited number of clients and employs a team incorporating finance and research professionals.

Investment Strategy

Ikarian Capital employs a long/short equity strategy, specializing in the healthcare and biotechnology sectors. The portfolio shows a dynamic approach, utilizing derivatives such as puts and calls on sector-relevant indices and companies. The fund actively manages sector, market, and security-specific exposures, aiming to capture alpha through deep company research and sector rotation while managing risk across long and short positions.

Top Buys
C
CDTXCIDARA THERAPEUTICS INC
+$17.3M
A
APGEAPOGEE THERAPEUTICS INC
+$10.1M
I
INSMINSMED INC
+$10.0M
A
ALNYALNYLAM PHARMACEUTICALS INC
+$9.9M
C
COGTCOGENT BIOSCIENCES INC
+$7.4M
Top Sells
T
TARSTARSUS PHARMACEUTICALS INC
-$17.0M
S
SPYSPDR S&P 500 ETF TR
-$14.0M
B
BPMCBLUEPRINT MEDICINES CORP
-$10.1M
R
RAREULTRAGENYX PHARMACEUTICAL IN
-$7.9M
E
EWTXEDGEWISE THERAPEUTICS INC
-$6.2M

Top Holdings

C
CDTXCIDARA THERAPEUTICS INC
+4.3%$22.6M
A
ALNYALNYLAM PHARMACEUTICALS INC
+3.5%$18.5M
I
INSMINSMED INC
+3.2%$16.5M
V
VRNAVERONA PHARMA PLC
+2.7%$13.9M
C
CRNXCRINETICS PHARMACEUTICALS IN
+2.4%$12.5M

Equity Positions (97)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
C
CDTX
CIDARA THERAPEUTICS INC4.35%$22.6M464,488$34.77$48.71+$17.3M
A
ALNY
ALNYLAM PHARMACEUTICALS INC3.54%$18.5M56,594$294.79$326.09+$9.9M
I
INSM
INSMED INC3.17%$16.5M163,751$78.92$100.64+$10.0M
V
VRNA
VERONA PHARMA PLC2.67%$13.9M146,831$57.76$94.58+$5.6M
C
CRNX
CRINETICS PHARMACEUTICALS IN2.39%$12.5M433,431$27.72$28.76-$5.1M

Options Positions (10)

TickerSecurityActionTypeNotional ValueContractsUnderlying PricePremium PaidChange (Contracts)Change (Value)
C
CDTX
CIDARA THERAPEUTICS INCNew
Put
$24.4M5,016$48.71$48.71+5,016+$24.4M
R
RARE
ULTRAGENYX PHARMACEUTICAL INBought
Call
$20.5M5,631$36.36$36.33+4,500+$16.4M
S
SLNO
SOLENO THERAPEUTICS INCBought
Put
$16.8M2,000$83.78$67.68+1,000+$9.6M
S
SLNO
SOLENO THERAPEUTICS INCSold
Call
$16.8M2,000$83.78$71.45-430-$606.4K
C
CDTX
CIDARA THERAPEUTICS INCNew
Call
$15.6M3,210$48.71$48.71+3,210+$15.6M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+60.4%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+26.9%
ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS
+6.4%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+1.7%
SERVICES-MEDICAL LABORATORIES
+1.3%

Investment Team (2)

NameRoleLocationLinkedIn
Emory Snowden
Emory Snowden
AnalystDallas, TX , United States
Nickolay Voronin
Nickolay Voronin
Pharma and Biotech Senior Research AnalystPlano, TX , United States