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MPM Asset Management LLC

CIK:0001263048
Venture Capital
$3B AUM
5 holdings
Boston, MA, United States
Founded:1997
53 employees
Latest filing:Jun 30, 2025

MPM Asset Management LLC, now operating under the name MPM BioImpact, is a Boston-based investment adviser and asset manager specializing in life sciences and biotechnology investments. The firm was founded in 1997 and manages venture capital and public equity strategies focused on the biotech and healthcare sectors. MPM serves institutional investors, academic endowments, and other sophisticated entities with a team of approximately 50 professionals, including scientists, clinicians, and investment specialists. The firm is deeply involved in company creation and growth, often leading investments in early-stage and emerging companies developing transformative therapeutics.

Investment Strategy

MPM focuses on investing in and building innovative biotechnology companies, particularly those developing breakthrough therapies in areas of high unmet medical need. The firm takes an active approach to company creation, leveraging scientific, clinical, and operational expertise to guide portfolio companies from early discovery through clinical development and potential commercialization. MPM often partners with leading academic institutions and pharma, aiming to create value through strategic guidance, operational support, and growth capital. The firm's investment philosophy emphasizes significant scientific innovation and attractive risk-adjusted returns across private and public markets within life sciences.

Top Buys
T
TRDAEntrada Therapeutics, Inc.
-$10.2M
D
DYNDyne Therapeutics, Inc.
-$641.4K
H
HOWLWerewolf Therapeutics, Inc.
+$508.6K
R
RPTXRepare Therapeutics, Inc.
+$453.0K
A
ADAPAdaptimmune Therapeutics plc
+$101.7K
Top Sells
T
TRDAEntrada Therapeutics, Inc.
-$10.2M
D
DYNDyne Therapeutics, Inc.
-$641.4K
H
HOWLWerewolf Therapeutics, Inc.
+$508.6K
R
RPTXRepare Therapeutics, Inc.
+$453.0K
A
ADAPAdaptimmune Therapeutics plc
+$101.7K

Top Holdings

T
TRDAEntrada Therapeutics, Inc.
+67.9%$29.4M
D
DYNDyne Therapeutics, Inc.
+15.0%$6.5M
H
HOWLWerewolf Therapeutics, Inc.
+10.8%$4.7M
R
RPTXRepare Therapeutics, Inc.
+3.6%$1.6M
A
ADAPAdaptimmune Therapeutics plc
+2.7%$1.2M

Equity Positions (5)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
T
TRDA
Entrada Therapeutics, Inc.67.92%$29.4M4,381,062$17.12$6.72-$10.2M
D
DYN
Dyne Therapeutics, Inc.14.99%$6.5M682,376$20.19$9.52-$641.4K
H
HOWL
Werewolf Therapeutics, Inc.10.84%$4.7M4,309,860$17.34$1.09+$508.6K
R
RPTX
Repare Therapeutics, Inc.3.60%$1.6M1,121,318$31.02$1.39+$453.0K
A
ADAP
Adaptimmune Therapeutics plc2.66%$1.2M4,809,677$0.93$0.24+$101.7K

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+97.3%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+2.7%