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Omega Fund Management, LLC
Omega Fund Management, LLC is a Boston-based venture capital firm founded in 2004 focused on supporting exceptional founders and entrepreneurs developing impactful products and platforms across multiple therapeutic areas. The firm specializes in life sciences and biotechnology investments, operates internationally, and employs approximately 23 professionals, serving institutional investors and emerging companies in the healthcare and biopharmaceutical sectors.
Investment Strategy
Omega Fund Management specializes in providing venture capital to companies in the life sciences and healthcare sectors, targeting opportunities with transformative potential in biotechnology and therapeutics. The firm partners with exceptional scientific founders and entrepreneurs, leveraging its deep industry experience, operational expertise, and global network to accelerate portfolio company growth. Omega emphasizes impactful innovation, cross-stage investments, and long-term partnerships to maximize value creation.
Latest 13F Filing Activity
Omega Fund Management, LLC filed their most recent 13F report on Jun 30, 2025 disclosing 12 equity positions with a total 13F market value of $154M. The fund increased holdings in Upstream Bio Inc., Beta Bionics Inc., Sana Biotechnology, Inc. among other positions. Omega Fund Management, LLC reduced exposure to Kestra Med Technologies LTD., Bicara Therapeutics Inc., Alumis Inc. among others.
Top Holdings
Equity Positions (12)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
B BBNX | Beta Bionics Inc. | 18.75% | $28.9M | 1,988,287 | $12.24 | $14.56 | +$4.6M |
K KMTS | Kestra Med Technologies Ltd. | 17.67% | $27.3M | 1,645,893 | $24.92 | $16.58 | -$17.5M |
U UPB | Upstream Bio Inc. | 14.48% | $22.4M | 2,036,293 | $16.44 | $10.98 | +$9.9M |
N NUVB | Nuvation Bio | 13.94% | $21.5M | 11,042,728 | $10.45 | $1.95 | -$1.5M |
B BCAX | Bicara Therapeutics Inc. | 13.26% | $20.5M | 2,204,650 | $25.47 | $9.29 | -$8.2M |
Industry Allocation
Investment Team (2)
| Name | Role | Location | |
|---|---|---|---|
N Noelle Hutchins | Senior Associate | Boston, MA , United States | |
 | Partner | United States |
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