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TRV GP VI, LLC

CIK:0001990716
Venture Capital
$1B AUM
4 holdings
Boston, MA, United States
Founded:2023
100 employees
Latest filing:Jun 30, 2025

TRV GP VI, LLC is the general partner entity for Third Rock Ventures VI, L.P., a venture capital fund managed by Third Rock Ventures. Founded in Boston, Massachusetts, Third Rock Ventures is a prominent venture capital firm specializing in early-stage investments in life sciences, primarily biotech companies. The firm manages multiple fund vehicles and is recognized for launching and backing innovative healthcare and biotechnology startups. TRV GP VI, LLC supports a portfolio focused on companies developing transformative therapies, with a strong presence in the US life sciences ecosystem. While the exact employee count for TRV GP VI, LLC is unavailable, Third Rock Ventures employs approximately 51-100 people.

Investment Strategy

The investment strategy of TRV GP VI, LLC, through Third Rock Ventures, centers on early-stage and company-creation investments in life sciences, particularly transformational biotechnology and therapeutics. The firm typically forms and leads new companies around breakthrough scientific discoveries, providing both capital and hands-on operational expertise. Their approach involves working closely with entrepreneurs and academic founders to build platform companies capable of addressing significant unmet medical needs, with a focus on high-impact, innovative science.

Top Buys
S
SEPNSEPTERNA, INC.
+$20.1M
R
RAPPRAPPORT THERAPEUTICS, INC.
+$1.3M
T
TNGXTANGO THERAPEUTICS, INC.
+$728.2K
C
CRGXCARGO THERAPEUTICS, INC.
+$93.4K
Top Sells
S
SEPNSEPTERNA, INC.
+$20.1M
R
RAPPRAPPORT THERAPEUTICS, INC.
+$1.3M
T
TNGXTANGO THERAPEUTICS, INC.
+$728.2K
C
CRGXCARGO THERAPEUTICS, INC.
+$93.4K

Top Holdings

S
SEPNSEPTERNA, INC.
+69.3%$44.5M
R
RAPPRAPPORT THERAPEUTICS, INC.
+17.2%$11.0M
C
CRGXCARGO THERAPEUTICS, INC.
+12.0%$7.7M
T
TNGXTANGO THERAPEUTICS, INC.
+1.5%$994.2K

Equity Positions (4)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
S
SEPN
SEPTERNA, INC.69.32%$44.5M4,211,659$18.60$10.57+$20.1M
R
RAPP
RAPPORT THERAPEUTICS, INC.17.16%$11.0M969,218$17.74$11.37+$1.3M
C
CRGX
CARGO THERAPEUTICS, INC.11.98%$7.7M1,867,119$14.42$4.12+$93.4K
T
TNGX
TANGO THERAPEUTICS, INC.1.55%$994.2K194,174$3.09$5.12+$728.2K

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+88.0%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+12.0%