Sign in

Flagship Pioneering Inc.

CIK:0001400240
Venture Capital
$3B AUM
4 holdings
Cambridge, MA, United States
Founded:1999
400 employees
Latest filing:Jun 30, 2025

Flagship Pioneering is a leading American life sciences venture capital company headquartered in Cambridge, Massachusetts. Founded in 1999 (originally as NewcoGen), the firm invents, incubates, and funds biotechnology and health-focused companies, having founded and built over 100 bioplatform companies such as Moderna and Editas Medicine. It employs a large team of scientist-entrepreneurs, business operators, and professionals, serving early-stage startups and portfolio companies in the life sciences and sustainability sectors.

Investment Strategy

Flagship Pioneering's investment strategy centers on creating and incubating breakthrough companies by generating bold "what-if" scientific questions and building novel bioplatforms in-house. The firm focuses on high-impact opportunities in biotechnology, health, and sustainability, often developing first-in-category business models to address significant global challenges. Their approach combines rigorous science with an entrepreneurial process, prioritizing the development of transformative technologies and enduring value through their unique, hands-on innovation model.

Top Buys
S
SANASana Biotechnology Inc
+$26.3M
F
FHTXFoghorn Therapeutics Inc
+$13.3M
M
MCRBSeres Therapeutics Inc
+$12.8M
M
MRNAModerna Inc
-$3.5M
Top Sells
S
SANASana Biotechnology Inc
+$26.3M
M
MCRBSeres Therapeutics Inc
-$16.2M
F
FHTXFoghorn Therapeutics Inc
+$13.3M
M
MCRBSeres Therapeutics Inc
+$12.8M
M
MRNAModerna Inc
-$3.5M

Top Holdings

M
MRNAModerna Inc
+47.6%$127.8M
S
SANASana Biotechnology Inc
+25.4%$68.3M
F
FHTXFoghorn Therapeutics Inc
+22.2%$59.6M
M
MCRBSeres Therapeutics Inc
+4.8%$12.8M

Equity Positions (4)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
M
MRNA
Moderna Inc47.60%$127.8M4,632,149$15.27$27.59-$3.5M
S
SANA
Sana Biotechnology Inc25.42%$68.3M25,001,856$33.47$2.73+$26.3M
F
FHTX
Foghorn Therapeutics Inc22.19%$59.6M12,674,120$20.27$4.70+$13.3M
M
MCRB
Seres Therapeutics Inc4.78%$12.8M1,155,850$11.11$11.11+$12.8M

Industry Allocation

BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+73.0%
PHARMACEUTICAL PREPARATIONS
+27.0%