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Flagship Pioneering Inc.
Flagship Pioneering is a leading American life sciences venture capital company headquartered in Cambridge, Massachusetts. Founded in 1999 (originally as NewcoGen), the firm invents, incubates, and funds biotechnology and health-focused companies, having founded and built over 100 bioplatform companies such as Moderna and Editas Medicine. It employs a large team of scientist-entrepreneurs, business operators, and professionals, serving early-stage startups and portfolio companies in the life sciences and sustainability sectors.
Investment Strategy
Flagship Pioneering's investment strategy centers on creating and incubating breakthrough companies by generating bold "what-if" scientific questions and building novel bioplatforms in-house. The firm focuses on high-impact opportunities in biotechnology, health, and sustainability, often developing first-in-category business models to address significant global challenges. Their approach combines rigorous science with an entrepreneurial process, prioritizing the development of transformative technologies and enduring value through their unique, hands-on innovation model.
Latest 13F Filing Activity
Flagship Pioneering Inc. filed their most recent 13F report on Jun 30, 2025 disclosing 4 equity positions with a total 13F market value of $268M. The fund increased holdings in Sana Biotechnology Inc., Foghorn Therapeutics Inc., Seres Therapeutics Inc. among other positions. Flagship Pioneering Inc. reduced exposure to Seres Therapeutics Inc., Moderna Inc., Seres Therapeutics Inc. among others.
Top Holdings
Equity Positions (4)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
M MRNA | Moderna Inc | 47.60% | $127.8M | 4,632,149 | $15.27 | $27.59 | -$3.5M |
S SANA | Sana Biotechnology Inc | 25.42% | $68.3M | 25,001,856 | $33.47 | $2.73 | +$26.3M |
F FHTX | Foghorn Therapeutics Inc | 22.19% | $59.6M | 12,674,120 | $20.27 | $4.70 | +$13.3M |
M MCRB | Seres Therapeutics Inc | 4.78% | $12.8M | 1,155,850 | $11.11 | $11.11 | +$12.8M |
Industry Allocation
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