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BeyondSpring (BYSI)

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Earnings summaries and quarterly performance for BeyondSpring.

Recent press releases and 8-K filings for BYSI.

BeyondSpring Reports Positive Phase 3 DUBLIN-3 Asian Subset Data for Plinabulin
BYSI
New Projects/Investments
  • BeyondSpring announced positive results from the Asian subset (n=488) of its global Phase 3 DUBLIN-3 trial, evaluating Plinabulin plus docetaxel compared to docetaxel alone in second- or third-line EGFR wild-type non-small cell lung cancer (NSCLC).
  • In this cohort, Plinabulin + docetaxel achieved a statistically significant improvement in overall survival (OS), with 10.8 months versus 8.8 months for docetaxel alone (HR 0.81, p=0.0426).
  • The combination also demonstrated a marked reduction in docetaxel-induced grade 4 neutropenia (DP: 3.9% vs. D: 26.5%, p<0.0001), indicating a favorable tolerability profile.
  • These findings strengthen the evidence for Plinabulin's potential as a new standard of care and support its advancement into a global Phase 3 confirmatory study.
Dec 12, 2025, 12:00 PM
BeyondSpring Announces Positive DUBLIN-3 Phase 3 Study Analyses and Plans for DUBLIN-4 Trial
BYSI
New Projects/Investments
  • BeyondSpring announced new post-hoc analyses from its Phase 3 DUBLIN-3 Study, presented at NACLC 2025, demonstrating that Plinabulin plus docetaxel provides clinically meaningful benefits for EGFR wild-type non-squamous NSCLC patients who progressed after anti-PD-(L)1 immunotherapy.
  • The combination showed improved median overall survival of 15.8 months compared to 11.7 months for docetaxel alone, and an objective response rate of 18.2% versus 8.0%.
  • Plinabulin also demonstrated improved safety by significantly reducing docetaxel-induced grade 4 neutropenia (5.13% vs. 33.58%) and reduced the incidence of new brain metastasis to 4.32% compared to 7.83% for docetaxel alone.
  • BeyondSpring plans to initiate a global Phase 3 DUBLIN-4 trial to serve as a confirmatory study, which, along with DUBLIN-3, is expected to support a future New Drug Application (NDA) submission.
Dec 11, 2025, 12:00 PM
BeyondSpring Inc. completes registered offering of ordinary shares
BYSI
  • BeyondSpring Inc. entered into a Securities Purchase Agreement with Ray Beauty Group Limited on November 17, 2025.
  • The company agreed to sell 800,000 ordinary shares at a purchase price of $2.50 per share.
  • This transaction resulted in gross proceeds of $2.0 million for BeyondSpring Inc..
  • The closing of the purchase and sale of the shares occurred on November 21, 2025.
  • Ray Beauty Group Limited, as the investor, is subject to a 60-day lock-up period from the closing date, during which it cannot sell the shares without prior written consent.
Nov 21, 2025, 9:30 PM
BeyondSpring Inc. Reports Q3 2025 Financial Results and Corporate Updates
BYSI
Earnings
New Projects/Investments
Accounting Changes
  • BeyondSpring Inc. reported a net loss attributable to the company of $1.540 million for Q3 2025, an improvement from a net loss of $2.132 million in Q3 2024.
  • Cash and cash equivalents significantly increased to $12.5 million as of September 30, 2025, compared to $2.9 million as of December 2024.
  • For continuing operations, Research and development expenses increased to $1.0 million in Q3 2025 from $0.6 million in Q3 2024, while General and administrative expenses decreased to $0.8 million from $1.7 million over the same period.
  • SEED Therapeutics, in which BeyondSpring holds a 38% equity share, completed a $30 million Series A-3 financing and received U.S. FDA and China NMPA clearance for its lead RBM39 degrader program's Investigational New Drug (IND) application.
Nov 12, 2025, 12:00 PM