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Corvus Pharmaceuticals (CRVS)

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Earnings summaries and quarterly performance for Corvus Pharmaceuticals.

Recent press releases and 8-K filings for CRVS.

Corvus Pharmaceuticals Presents Final Phase 1/1b Data for Soquelitinib in T Cell Lymphoma
CRVS
New Projects/Investments
  • Corvus Pharmaceuticals presented final data from its Phase 1/1b trial of soquelitinib in patients with T cell lymphoma at the 67th American Society of Hematology Annual Meeting & Exposition.
  • In the 200 mg BID cohort (N=24) of relapsed/refractory PTCL patients, the trial demonstrated a median progression-free survival of 6.2 months and a median overall survival of 28.1 months.
  • This cohort also showed objective responses in 9 of 24 patients, including 6 complete responses, with no dose-limiting toxicities or significant adverse events observed.
  • The data supports the ongoing registration Phase 3 trial for soquelitinib in relapsed/refractory PTCL, with interim data anticipated in late 2026 and trial completion in 2027.
  • Soquelitinib has received Orphan Drug Designation for T cell lymphoma and Fast Track designation for relapsed/refractory PTCL from the FDA.
Dec 8, 2025, 3:30 PM
Corvus Pharmaceuticals Provides Update on Soquelitinib Development and Financial Runway
CRVS
New Projects/Investments
Guidance Update
  • Corvus Pharmaceuticals (CRVS) is a clinical-stage company focused on developing first-in-class immune modulators, with its lead program, soquelitinib, in a Phase III registrational trial for peripheral T-cell lymphoma (PTCL) and a Phase Ib/soon-to-be Phase II trial for moderate to severe atopic dermatitis (AD).
  • In atopic dermatitis, soquelitinib has demonstrated a safe profile and statistical separation from placebo at 28 days in initial cohorts, with a potential for a prolonged effect.
  • The company is advancing soquelitinib into a global Phase II study for AD, a 12-week trial with an expected data readout in 2027.
  • Corvus identifies a significant commercial opportunity in AD, estimating each 1% market share to be worth $1 billion, and plans to initiate an asthma study in 2026.
  • As of September 30, Corvus reported $65 million in cash, providing a financial runway through Q4 2026.
Nov 10, 2025, 1:30 PM
Corvus Pharmaceuticals Reports Q3 2025 Financials and Soquelitinib Clinical Progress
CRVS
Earnings
New Projects/Investments
Board Change
  • Corvus Pharmaceuticals reported a net loss of $10.2 million for the Third Quarter 2025, compared to a net loss of $40.2 million for the same period in 2024. Research and development expenses for Q3 2025 totaled $8.5 million, an increase from $5.2 million in Q3 2024.
  • As of September 30, 2025, Corvus had $65.7 million in cash, cash equivalents, and marketable securities, and expects this cash to fund operations into the Fourth Quarter of 2026.
  • For soquelitinib, results from the Extension Cohort 4 of the Phase I atopic dermatitis trial are anticipated to be reported in January 2026, and the Phase II atopic dermatitis trial is on track to begin in early Q1 2026.
  • Enrollment is ongoing for the registrational Phase III trial of soquelitinib in relapsed Peripheral T-cell Lymphoma (PTCL), with interim data expected in late 2026.
  • David Moore was appointed to the Board of Directors in October.
Nov 4, 2025, 9:30 PM
Corvus Pharmaceuticals Provides Business Update and Reports Q3 2025 Financial Results
CRVS
Earnings
Guidance Update
New Projects/Investments
  • Corvus Pharmaceuticals reported a net loss of $10.2 million for the third quarter ended September 30, 2025, compared to a net loss of $40.2 million for the same period in 2024.
  • Research and development expenses for Q3 2025 were $8.5 million, an increase from $5.2 million in Q3 2024, primarily due to higher clinical trial and manufacturing costs for soquelitinib.
  • As of September 30, 2025, the company held $65.7 million in cash, cash equivalents, and marketable securities, and expects this cash to fund operations into the fourth quarter of 2026.
  • The company completed enrollment in extension cohort 4 of the soquelitinib atopic dermatitis Phase 1 clinical trial, with data anticipated in January 2026, and is on track to initiate a Phase 2 clinical trial in early Q1 2026.
  • Enrollment continues in the registrational Phase 3 clinical trial of soquelitinib in relapsed/refractory peripheral T cell lymphoma (PTCL), and final Phase 1/1b results for T cell lymphoma will be presented at the American Society of Hematology Annual Meeting in December 2025.
Nov 4, 2025, 9:01 PM
CRVS Provides Update on Soquelitinib Development and Clinical Trials
CRVS
New Projects/Investments
  • CRVS is advancing Soquelitinib, an ITK inhibitor, with a randomized Phase 3 trial currently enrolling for Peripheral T-cell Lymphoma (PTCL), which could be the first fully FDA-approved drug for PTCL.
  • In a Phase 1 study for moderate to severe Atopic Dermatitis (AD), Soquelitinib demonstrated favorable safety and tolerability, with Cohort 3 showing a mean EASI reduction of 64.8% and 25% of patients achieving IGA 0 or 1 at 4 weeks.
  • Soquelitinib also showed clinically meaningful reductions in patient-reported pruritus (itch), with 50% of evaluable patients in Cohort 3 achieving a ≥4-point decrease in PP-NRS at Day 28.
  • Key upcoming milestones include Phase 1 extension cohort 4 data for Atopic Dermatitis in January 2026 and Phase 2 trial initiation in early Q1 2026.
Nov 4, 2025, 9:00 PM
Corvus Pharmaceuticals Presents Interim Phase 1b/2 Clinical Trial Data for Ciforadenant in Metastatic RCC
CRVS
New Projects/Investments
  • Corvus Pharmaceuticals (CRVS) announced the presentation of interim data from its Phase 1b/2 clinical trial of ciforadenant for metastatic renal cell cancer (RCC) at the European Society for Medical Oncology (ESMO) Congress 2025 on October 17, 2025.
  • The triplet therapy, combining ciforadenant with ipilimumab and nivolumab, was found to be feasible and well tolerated in patients with unfavorable disease characteristics.
  • As of May 2025, the trial demonstrated a deep response rate of 34%, an objective response rate (ORR) of 46% (including two complete responses and 21 partial responses), and a median progression-free survival (PFS) of 11.04 months.
  • The 34% deep response rate shows an improvement compared to historical data of 32% for the doublet therapy alone, though it is not yet statistically significant.
  • Nineteen patients remain on therapy for longer follow-up to further assess the potential benefits of blocking adenosine signaling with ciforadenant.
Oct 17, 2025, 2:00 PM
Corvus Pharmaceuticals Provides Pipeline Update at Oppenheimer Healthcare Conference
CRVS
New Projects/Investments
Guidance Update
  • Corvus Pharmaceuticals' lead program, Socalitinib, is in a Phase 3 registrational trial for peripheral T cell lymphoma (PTCL) with data expected by mid-2026, and a Phase 1 trial for atopic dermatitis (AD), for which full data readout was expected in Q2 2025.
  • A solid tumor study in renal cell carcinoma (RCC) was planned to start in Q2 2025, with data anticipated in H1 2026. Additionally, a Phase 2 trial for autoimmune lymphoproliferative syndrome (ALPS) was planned to start in March 2025, and initiation of a Phase 2 AD trial was planned for the second half of 2025.
  • Preliminary efficacy data from the Phase 1 AD trial (cohorts 1 and 2) showed a 69% mean EASI reduction for the active arm at eight weeks, compared to 19% for placebo, and zero placebo responses in IgA 0,1 and EASI 75 endpoints, alongside a very attractive safety and tolerability profile.
  • Corvus is also developing next-generation ITK inhibitors, which are approximately 12 to 15 months from entering the clinic.
Feb 11, 2025, 2:20 PM