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Kiniksa Pharmaceuticals International (KNSA)

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Earnings summaries and quarterly performance for Kiniksa Pharmaceuticals International.

Recent press releases and 8-K filings for KNSA.

Kiniksa Pharmaceuticals International announces Q4 and Full Year 2025 Financial Results
KNSA
Earnings
Guidance Update
Revenue Acceleration/Inflection
  • Kiniksa Pharmaceuticals International reported ARCALYST revenue of $202.1 million for Q4 2025 and $677.6 million for the full year 2025, representing approximately 62% year-over-year growth.
  • The company achieved a net income of $59.0 million for the full year 2025.
  • Kiniksa provided 2026 ARCALYST revenue guidance of $900-920 million.
  • The company ended 2025 with a strong financial position, holding $414.1 million in cash, cash equivalents, and short-term investments as of December 31, 2025, and anticipates remaining cash flow positive on an annual basis.
  • Key pipeline advancements include Phase 2 data for KPL-387 expected in 2H 2026 and the KPL-1161 Phase 1 trial initiating by the end of 2026.
4 days ago
Kiniksa Pharmaceuticals International Reports Strong Q4 and Full Year 2025 Results, Provides 2026 Arcalyst Guidance
KNSA
Earnings
Guidance Update
Revenue Acceleration/Inflection
  • Kiniksa Pharmaceuticals International reported Arcalyst product revenue of $202.1 million in Q4 2025, a 65% year-over-year increase, and $677.6 million for the full year 2025, a 62% increase. The company achieved a net income of $14.2 million in Q4 2025 and $59 million for the full year 2025, ending the year with $414.1 million in cash.
  • For full year 2026, Kiniksa expects Arcalyst net revenue to be between $900 million and $920 million.
  • Arcalyst's penetration into the 2-plus recurrence target market reached approximately 18% by the end of 2025, an increase from 13% at the end of 2024.
  • The company is advancing its pipeline, with KPL-387 in a Phase 2/3 clinical trial and Phase 2 data expected in the second half of 2026, and plans to initiate clinical trials for KPL-1161 by the end of 2026.
4 days ago
Kiniksa Reports Strong Q4 and Full Year 2025 Financial Results, Provides 2026 Revenue Guidance
KNSA
Earnings
Guidance Update
Revenue Acceleration/Inflection
  • Kiniksa reported Arcalyst product revenue of $202.1 million for Q4 2025, a 65% year-over-year increase, and $677.6 million for the full year 2025, representing 62% year-over-year growth. The company achieved a net income of $14.2 million in Q4 2025 and $59 million for the full year 2025, a significant improvement from net losses in the prior year.
  • For the full year 2026, Kiniksa reiterates its net revenue guidance for Arcalyst to be between $900 million and $920 million.
  • Arcalyst's penetration into the 2-plus recurrence target market reached approximately 18% by the end of 2025, up from 13% at the end of 2024. Over 4,150 prescribers have written a prescription for Arcalyst, with more than 1,200 having written for two or more patients.
  • The company is advancing its pipeline, with data from the Phase 2 portion of the KPL-387 clinical trial expected in the second half of 2026, aiming for a launch in the 2028-2029 timeframe. Additionally, KPL-1161 is planned to enter the clinic by the end of 2026.
4 days ago
Kiniksa Pharmaceuticals International Reports Strong Q4 and Full-Year 2025 Financial Results
KNSA
Earnings
Guidance Update
Revenue Acceleration/Inflection
  • Kiniksa Pharmaceuticals International reported ARCALYST product revenue of $202.1 million in Q4 2025, representing a 65% year-over-year increase, and $677.6 million for the full year 2025, up 62% from the previous year.
  • The company achieved net income of $14.2 million in Q4 2025 and $59 million for the full year 2025, a significant improvement from net losses in the prior year.
  • Kiniksa ended 2025 with $414.1 million in cash, having generated $170.4 million in net cash during the year, and expects to remain cash flow positive on an annual basis under its current operating plan.
  • The company reiterated its full-year 2026 net revenue guidance for ARCALYST of between $900 million and $920 million.
  • ARCALYST's market penetration into the two-plus recurrence target market increased to approximately 18% by the end of 2025, and the pipeline asset KPL-387 is on track for Phase II data in the second half of 2026.
4 days ago
Kiniksa Pharmaceuticals Reports Q4 and Full Year 2025 Financial Results and 2026 Guidance
KNSA
Earnings
Guidance Update
New Projects/Investments
  • ARCALYST net product revenue was $202.1 million for the fourth quarter of 2025 and $677.6 million for the full year 2025.
  • Kiniksa expects ARCALYST net product revenue for 2026 to be between $900 million and $920 million.
  • For the full year 2025, the company reported total revenue of $677.6 million and net income of $59.0 million.
  • As of December 31, 2025, Kiniksa held $414.1 million in cash, cash equivalents, and short-term investments, with no debt.
  • Kiniksa anticipates KPL-387 Phase 2 recurrent pericarditis data in the second half of 2026 and plans to initiate a KPL-1161 Phase 1 trial by the end of 2026.
4 days ago
Kiniksa Pharmaceuticals Provides Corporate Update and 2026 ARCALYST Revenue Guidance
KNSA
Guidance Update
New Projects/Investments
Revenue Acceleration/Inflection
  • Kiniksa Pharmaceuticals reported unaudited ARCALYST net product revenue of $677.5 million for the full year 2025, marking approximately 62% year-over-year growth from $417.0 million in 2024.
  • The company projects 2026 ARCALYST net product revenue to be between $900 million and $920 million.
  • As of December 31, 2025, Kiniksa held an unaudited cash, cash equivalents, and short-term investments balance of $414.1 million, with no debt.
  • Kiniksa expects KPL-387 Phase 2 recurrent pericarditis data in the second half of 2026 and plans to initiate a KPL-1161 Phase 1 trial by the end of 2026.
Jan 12, 2026, 10:22 PM
Kiniksa Reports Strong ARCALYST Revenue and Provides 2026 Guidance
KNSA
Guidance Update
Revenue Acceleration/Inflection
New Projects/Investments
  • Kiniksa reported full year 2025 unaudited net revenue of $677.5 million for ARCALYST, representing 62% year-over-year growth, and issued 2026 net product revenue guidance of $900-$920 million.
  • ARCALYST has generated around $1.5 billion in cumulative net revenue since its launch and is being positioned as the second-line standard of care for recurrent pericarditis, supported by new ACC clinical guidance.
  • The company is advancing KPL-387 in a Phase 2/3 study for recurrent pericarditis, with dose-focusing data expected in the second half of 2026 and a commercialization target of 2028-2029.
  • Kiniksa also plans for KPL-1161 to enter the clinic by the end of 2026 and reported around $414 million in year-end cash reserves.
Jan 12, 2026, 10:15 PM
Kiniksa Updates on ARCALYST Performance and Pipeline Progress
KNSA
Guidance Update
Revenue Acceleration/Inflection
New Projects/Investments
  • Kiniksa reported full year 2025 unaudited net revenue of $677.5 million for ARCALYST, representing 62% year-over-year growth, and provided 2026 net product revenue guidance of $900-$920 million.
  • The company is advancing its clinical portfolio, with KPL-387 in a phase 2/3 study for recurrent pericarditis, expecting dose-focusing data in the second half of 2026, and KPL-1161 anticipated to enter the clinic by the end of 2026.
  • Commercialization efforts for ARCALYST are focused on establishing it as the second-line standard of care for recurrent pericarditis, with 18% penetration into the multiple recurrent patient group by the end of 2025, up from 13% at the end of 2024.
  • Kiniksa ended the year with approximately $414 million in cash reserves and saw 325 additional new ARCALYST prescribers in Q4 2025, bringing the total to over 4,150 prescribers.
Jan 12, 2026, 10:15 PM
Kiniksa Reports Strong 2025 ARCALYST Revenue and Provides 2026 Guidance
KNSA
Guidance Update
Revenue Acceleration/Inflection
New Projects/Investments
  • Kiniksa announced full year 2025 unaudited net revenue for ARCALYST of $677.5 million, representing 62% year-over-year growth, and issued full year 2026 net product revenue guidance of $900-$920 million.
  • ARCALYST has generated approximately $1.5 billion in cumulative net revenue since its launch, and Kiniksa ended 2025 with around $414 million in cash reserves.
  • The company is advancing its pipeline, with KPL-387 in a Phase 2/3 study for recurrent pericarditis, expecting data from the dose-focusing portion in the second half of 2026 and targeting commercialization in 2028-2029.
  • Kiniksa also plans for KPL-1161, an Fc-modified IL-1 alpha and beta inhibitor, to enter the clinic by the end of 2026.
Jan 12, 2026, 10:15 PM
Kiniksa Reports Strong ARCALYST Performance and Advances Clinical Pipeline
KNSA
Guidance Update
New Projects/Investments
Earnings
  • Kiniksa (KNSA) projects ARCALYST revenue of $900M to $920M for 2026 and reported $180.9M in product revenue for Q3 2025, contributing to $18.4M in net income for the quarter.
  • The company maintained a strong financial position with approximately $414M in cash reserves at the end of 2025 and anticipates remaining cash flow positive on an annual basis.
  • ARCALYST has achieved ~$1.5B in net revenue since launch and has become the ACC-recommended second-line treatment for recurrent pericarditis, with its use increasing to 71% in 2023.
  • Kiniksa is advancing its clinical pipeline, with KPL-387 in a Phase 2/3 trial for recurrent pericarditis, expecting Phase 2 data in 2H 2026, and KPL-1161 initiating a Phase 1 trial by the end of 2026.
Jan 12, 2026, 12:00 PM

Quarterly earnings call transcripts for Kiniksa Pharmaceuticals International.