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Todd Chappell

Chief Operating Officer at Korro Bio
Executive

About Todd Chappell

Todd Chappell is Chief Operating Officer at Korro Bio (KRRO), serving since the November 2023 merger; he was Legacy Korro COO from August 2023 and previously SVP, Strategy & Portfolio Planning from March 2021. He is 51, holds an M.B.A. from Boston University and a B.S. in Biology from UCLA, with prior operating and venture-building roles across Rasio Therapeutics, Perceptive Navigation, BioHealth Innovation, Shape Pharmaceuticals, and CombinatoRx . During his tenure, the company reported negative net income of $81.2M in 2023 and $83.6M in 2024, and disclosed pay-versus-performance TSR values of $25 (2023) and $20 (2024), reflecting development-stage risk and equity volatility .

Past Roles

OrganizationRoleYearsStrategic Impact
Korro Bio (Legacy Korro)SVP, Strategy & Portfolio PlanningMar 2021–Aug 2023Portfolio planning; advanced early pipeline strategy
Korro Bio (Legacy Korro)Chief Operating OfficerAug 2023–Nov 2023Operational leadership pre-merger
Korro Bio (post-merger)Chief Operating OfficerNov 2023–PresentEnterprise-wide operations across OPERA RNA editing platform and programs
Rasio TherapeuticsChief Executive OfficerJun 2019–Mar 2021Built and led early-stage drug development company
Perceptive Navigation, LLCChief Executive OfficerJun 2015–May 2019Led medical device ventures; product advancement
BioHealth Innovation, Inc.Entrepreneur-in-ResidenceNot disclosedManaged portfolio of start-up pharma and medtech companies
Shape Pharmaceuticals (HealthCare Ventures portfolio)VP, OperationsNot disclosedOversaw day-to-day operations for HDAC inhibitor program for CTCL
CombinatoRx, Inc.Executive Director, New ProductsNot disclosedAdvanced three programs from assay stage into human studies

External Roles

  • No public-company board or external directorships disclosed for Chappell in KRRO’s filings reviewed .

Fixed Compensation

  • Chappell was not a named executive officer (NEO) in KRRO’s 2024 proxy disclosure; individual base salary, target bonus %, and actual bonus for him are not disclosed in the latest DEF 14A .
  • Company program context: 2024 NEO base salaries and bonus targets were set by the compensation committee using market benchmarks, with target bonuses tied to pipeline, OPERA platform, and corporate development goals .

Performance Compensation

  • Company annual incentive plan metrics for 2024 covered pipeline progress, OPERA platform development, and corporate development; overall achievement was determined at 95% of target for NEOs .
  • Specific metric weightings, individual targets, and payouts for Chappell are not disclosed in KRRO’s proxy .

Equity Ownership & Alignment

Data PointValueAs-ofSource
Form 3 beneficial ownership0 sharesEvent date 11/03/2023; filed 11/07/2023
Role at filingOfficer (COO)11/07/2023
Lock-up agreement post-merger180 days from 11/03/2023 closing (executives included)11/06/2023
Hedging/pledgingProhibited for all employees and directors (no margin or pledges)Insider Trading Policy filed with 2024 10-K

Notes:

  • Principal stockholder and officer ownership table in the 2025 proxy does not list Chappell among disclosed Directors/NEOs, so an updated beneficial ownership count for him is not provided there .
  • Securities authorized under equity plans at FY2024 year-end: 1,256,337 options outstanding (WAEP $25.42) and 788,590 shares available for future issuance; relevant to dilution and future award capacity .

Employment Terms

TermDetailsSource
IndemnificationCompany entered indemnification agreements with executive officers at merger closing
At-will employment & executive agreementsCompany executed new executive employment agreements around merger with enhanced change-in-control (CIC) severance constructs for executives
CIC severance (executive framework)Lump sum equal to 12 months base salary + 1.0x target bonus, up to 12 months COBRA, and acceleration of unvested time-based equity; CIC window = 3 months before to 12 months after
Outside CIC terminationCompany disclosed typical “cause,” “good reason,” disability provisions; good reason includes material diminution of duties, salary cut (broadly consistent clauses shown in executive agreements)
ClawbackCompensation recovery policy adopted Nov 3, 2023, retroactive to Oct 2, 2023, to recoup incentive pay upon required restatements
Anti-hedging/pledgingProhibits short sales, derivatives, hedges; prohibits pledging or margin

Note: While the company disclosed detailed terms for certain executives (e.g., CEO/CFO) and the CIC framework applicable to executive agreements broadly, a standalone Chappell employment agreement was not specifically filed in the reviewed documents; policy-level terms are applied here as company disclosures covering executive officers .

Company Performance During Chappell’s Tenure

MetricFY 2023FY 2024
Pay vs Performance – TSR value of initial $100 investment ($)$25 $20
Net Income (USD thousands)$(81,172) $(83,581)
Collaboration Revenue (USD millions)$0.0 $2.3
Development stage statusNo product sales; early-stage RNA editing platformNarrative

Compensation Committee & Governance Context

  • Compensation Committee: Nessan Bermingham (Chair), Ali Behbahani, Katharine Knobil, Timothy Pearson; met three times in 2024; external consultant Alpine Rewards engaged, with no conflicts noted .
  • Equity grant practices: annual grants effective first trading day in February; new hire/promotion grants effective the first trading day following the first of the month; committee avoids timing grants around MNPI; anti-hedging/pledging embedded in policy .

Risk Indicators & Red Flags

  • Hedging/pledging prohibited (reduces misalignment risk) .
  • Strong clawback policy adopted per SEC/Nasdaq rules .
  • No Form 144 selling notices for Chappell found in KRRO’s filing index search, limiting evidence of planned insider sales pressure from him; broader company notices exist but not linked to Chappell in results returned [Search attempted; none found].
  • Development-stage losses and equity volatility (TSR data) heighten compensation alignment scrutiny and retention risk given long-duration value creation cycles .

Investment Implications

  • Alignment: Anti-hedging/pledging, clawback policy, and CIC constructs suggest governance frameworks consistent with investor-friendly practices; however, lack of Chappell-specific disclosed pay metrics limits pay-for-performance assessment granularity .
  • Retention and selling pressure: Post-merger lock-up included Chappell (180 days), and absence of disclosed Form 144s for him reduces near-term sale signal; option-heavy plan capacity could create future dilution but aligns executives to long-term value realization .
  • Execution risk: Corporate TSR declines and sustained losses reflect development-stage profile; Chappell’s operating background across pharma/medtech portfolio execution is a positive for clinical and platform scaling, but value creation will hinge on KRRO-110 clinical data and OPERA platform milestones, not yet tied to disclosed PSU metrics or multi-year performance grids for him .