Jim Molloy

Thomas Yip

Ed Arce

James Molloy

Nazibur Rahman

Naz Rahman

- Talphera, Inc. announced the enrollment of **17 patients** in its **70-patient pivotal NEPHRO CRRT clinical trial**, representing approximately **25% enrollment**.  **[1427925_20250825SF57699:0]** 
- This **17-patient enrollment milestone** was a required condition to close the **second tranche of a three-tranche financing** that was announced in March 2025.  **[1427925_20250825SF57699:0]** 
- The company remains **on track for planned study completion by the end of 2025**, with an accelerated recruitment rate where **over 90% of enrolled patients are now from new target profile sites**.  **[1427925_20250825SF57699:0]**

TALPHERA (TLPH)