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First Turn Management, LLC

CIK:0001993440
Hedge Fund
$536M AUM
35 holdings
Del Mar, CA, US
Founded:2023
2 employees
Latest filing:Jun 30, 2025

First Turn Management, LLC is an SEC-registered investment adviser based in Del Mar, California. The firm manages several pooled investment vehicles and institutional accounts, with reported assets under management over $500 million as of mid-2025. With a small, highly focused team, the firm serves mainly pooled investment vehicles, government entities, and foreign institutional investors. First Turn Management, LLC appears to have commenced operations in or after 2023, coinciding with the earliest available public SEC filings.

Investment Strategy

First Turn Management, LLC focuses on fundamental, research-driven equity investing, targeting long and short positions primarily in the healthcare and biotechnology sectors. The firm actively manages concentrated portfolios, dynamically adjusting positions based on detailed sector research, market events, and valuation changes, and takes a disciplined approach to risk and capital allocation. The firm appears to employ a bottom-up process driven by deep sector expertise, and positions are regularly adjusted based on ongoing research and developments within core holdings.

Latest 13F Filing Activity

First Turn Management, LLC filed their most recent 13F report on Jun 30, 2025 disclosing 35 equity positions with a total 13F market value of $536M. The fund increased holdings in Disc Medicine Inc., Arcellx Inc., Newamsterdam Pharma Company among other positions. First Turn Management, LLC reduced exposure to Springworks Therapeutics Inc., Glaukos Corp., Exact Sciences Corp. among others.

Top Buys
I
IRONDISC MEDICINE INC
+$15.9M
A
ACLXARCELLX INC
+$14.2M
N
NAMSNEWAMSTERDAM PHARMA COMPANY
+$9.4M
O
ORICORIC PHARMACEUTICALS INC
+$9.1M
A
ADMAADMA BIOLOGICS INC
+$8.6M
Top Sells
S
SWTXSPRINGWORKS THERAPEUTICS INC
-$13.4M
G
GKOSGLAUKOS CORP
-$13.4M
E
EXASEXACT SCIENCES CORP
-$13.0M
P
PCVXVAXCYTE INC
-$10.5M
B
BPMCBLUEPRINT MEDICINES CORP
-$8.1M

Top Holdings

I
INSMINSMED INC
+7.0%$37.5M
V
VRNAVERONA PHARMA PLC
+5.5%$29.3M
M
MIRMMIRUM PHARMACEUTICALS INC
+5.0%$26.8M
N
NUVLNUVALENT INC
+4.6%$24.5M
A
ARGXARGENX SE
+4.5%$24.2M

Equity Positions (35)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
INSMED INC7.00%$37.5M372,672$67.38$100.64+$6.9M
VERONA PHARMA PLC5.47%$29.3M309,988$30.67$94.58+$1.7M
MIRUM PHARMACEUTICALS INC5.01%$26.8M527,540$30.02$50.89+$4.2M
NUVALENT INC4.57%$24.5M320,798$81.46$76.30+$936.6K
ARGENX SE4.52%$24.2M43,953$388.36$551.22-$577.9K

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+75.0%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+23.0%
BLANK CHECKS
+3.9%
SERVICES-MEDICAL LABORATORIES
+2.0%