Earnings summaries and quarterly performance for GLAUKOS.
Executive leadership at GLAUKOS.
Board of directors at GLAUKOS.
Research analysts who have asked questions during GLAUKOS earnings calls.
Allen Gong
JPMorgan Chase & Co.
6 questions for GKOS
Larry Biegelsen
Wells Fargo & Company
6 questions for GKOS
Ryan Zimmerman
BTIG
6 questions for GKOS
Thomas Stephan
Stifel
6 questions for GKOS
Joanne Wuensch
Citigroup Inc.
5 questions for GKOS
Richard Newitter
Truist Securities
5 questions for GKOS
Adam Maeder
Piper Sandler Companies
4 questions for GKOS
Anthony Petrone
Mizuho Group
4 questions for GKOS
Mason Carrico
Stephens Inc.
4 questions for GKOS
Michael Sarcone
Jefferies
4 questions for GKOS
Danielle Antalffy
UBS Group AG
3 questions for GKOS
David Saxon
Needham & Company
3 questions for GKOS
Danielle Antalffy
UBS
2 questions for GKOS
David Roman
Goldman Sachs Group Inc.
2 questions for GKOS
David Saxon
Needham
2 questions for GKOS
Patrick Wood
Morgan Stanley
2 questions for GKOS
Steven Lichtman
Oppenheimer & Co. Inc.
2 questions for GKOS
K. Gong
JPMorgan Chase & Co.
1 question for GKOS
Macauley Kilbane
William Blair & Company
1 question for GKOS
Matthew O'Brien
Piper Sandler & Co.
1 question for GKOS
Ravi Misra
Truist Securities
1 question for GKOS
Steve Lichtman
William Blair
1 question for GKOS
Recent press releases and 8-K filings for GKOS.
- Glaukos Corporation reported 30% topline growth in 2025 and provided 2026 revenue guidance of $610 million, supported by a healthy balance sheet with $283 million in cash and equivalents and no debt as of December 31, 2025.
- The company recently received FDA approval for iDose TR re-administration in January 2026 and Epioxa (Epi-on) in 2025, with Epioxa's launch timing set for 2026.
- Glaukos is advancing a robust pipeline of 13 disclosed programs, including lead candidates in its iLution platform (Demodex Blepharitis in Phase 2) and Retina XR platform (IVT multi-kinase inhibitor in Phase 2a for AMD, DME, RVO).
- Glaukos reported record fourth quarter 2025 consolidated net sales of $143.1 million, a 36% increase year-over-year, and full-year 2025 net sales of $507.4 million, up 32% from 2024.
- The company reaffirmed its full-year 2026 net sales guidance range of $600 million-$620 million, representing over 20% growth at the midpoint.
- iDose TR generated approximately $45 million in sales in Q4 2025 and $136 million for the full year 2025, with the U.S. FDA approving unlimited re-administration.
- Epioxa, a novel treatment for keratoconus, received FDA approval in Q4 2025, with drug availability expected late in Q1 2026 and a permanent J-code anticipated in July 2026.
- Operating expenses for 2026 are projected to be around $555 million-$560 million, reflecting mid-teen year-over-year growth off the 2025 base, while still showing operating leverage.
- Glaukos reported record fourth quarter 2025 consolidated net sales of $143.1 million, a 36% increase on a reported basis, and full-year 2025 consolidated net sales of $507.4 million, up 32% versus 2024.
- The company reaffirmed its full-year 2026 net sales guidance range of $600 million-$620 million, implying more than 20% year-over-year growth at the midpoint.
- The U.S. glaucoma franchise achieved record Q4 net sales of $86.4 million, significantly driven by iDose TR sales of approximately $45 million in Q4 and $136 million for the full year 2025.
- The U.S. FDA approved Epioxa for keratoconus, with drug availability expected late in Q1 2026 and a permanent J-code by July 2026. Additionally, the FDA approved a labeling supplement for iDose TR allowing for unlimited re-administration.
- Operating expenses are projected to increase by a mid-teen year-over-year percentage in 2026, reaching approximately $555 million-$560 million.
- Glaukos reported record Q4 2025 consolidated net sales of $143.1 million, a 36% increase year-over-year, and record full-year 2025 net sales of $507.4 million, up 32% from 2024.
- The company reaffirmed its full-year 2026 net sales guidance range of $600 million-$620 million, implying over 20% year-over-year growth at the midpoint.
- iDose TR sales reached approximately $45 million in Q4 2025 and $136 million for the full year 2025, contributing to a 53% year-over-year growth in the U.S. glaucoma franchise to $86.4 million in Q4 2025.
- The U.S. FDA approved an NDA labeling supplement for iDose TR, allowing unlimited re-administration; additionally, Epioxa is commercially available, with a permanent J-code anticipated in July 2026.
- Glaukos continues to advance a broad clinical pipeline, including patient enrollment in a PMA pivotal trial for iStent infinite and a phase 2B/3 clinical program for iDose T-Rex.
- Glaukos Corporation reported record net sales of $143.1 million in Q4 2025, an increase of 36% year-over-year, and $507.4 million for the full year 2025, up 32% year-over-year.
- The company's Non-GAAP gross margin was approximately 85% for Q4 2025 and 84% for the full year 2025.
- Glaukos reported a Non-GAAP net loss of $16.4 million, or ($0.28) per diluted share, for Q4 2025, and a Non-GAAP net loss of $51.7 million, or ($0.90) per diluted share, for the full year 2025.
- The company reaffirmed its 2026 net sales guidance of $600 million to $620 million and ended Q4 2025 with approximately $282.6 million in cash and cash equivalents, short-term investments, and restricted cash.
- Key operational updates include U.S. FDA approval for Epioxa (Epi-on) in October 2025, with commercial availability expected in Q1 2026, and U.S. FDA approval for unlimited re-administration of iDose TR in January 2026.
- Glaukos reported record net sales of $143.1 million in the fourth quarter of 2025, an increase of 36% year-over-year, and $507.4 million for the full year 2025, up 32% compared to 2024.
- The company provided 2026 net sales guidance in the range of $600 million to $620 million.
- For the fourth quarter of 2025, Glaukos reported a net loss of $133.7 million, or ($2.32) per diluted share, which included a one-time, non-cash impairment charge of $112.9 million related to an acquired intangible asset.
- The full year 2025 net loss was $187.7 million, or ($3.28) per diluted share, also impacted by the $112.9 million impairment charge.
- Glaukos ended the fourth quarter of 2025 with approximately $282.6 million in cash and cash equivalents, short-term investments, and restricted cash, with no debt.
- The FDA approved a labeling supplement for Glaukos's iDose TR, permitting repeat administration of the intracameral travoprost implant.
- This decision is supported by clinical evidence demonstrating favorable long-term corneal safety and sustained intraocular pressure reductions, with approximately 70% of iDose TR patients remaining well-controlled at 36 months.
- The market reacted positively, with Glaukos shares rising and Wells Fargo maintaining an Overweight rating with a $122 price target; Glaukos currently has a market capitalization of around $7.32 billion and reported approximately $469.8 million in revenue, though it faces profitability challenges with a negative operating margin of around -18.82%.
- Glaukos has invested $800 million in R&D since 2018, resulting in 12 commercially available products and 13 in development, and has achieved over 20% CAGR every year for 10 years with over 30% market growth in the past year. The company maintains an 84% gross margin profile and a healthy balance sheet of $283 million.
- The company is focused on transforming glaucoma and keratoconus treatment paradigms. For glaucoma, the iDose TR product demonstrated 81% of patients off all medications at one year in Phase III trials , and the next-generation iDose TREX, currently in Phase II-B/III clinical trials, is expected to last six years with a single injection.
- For keratoconus, Epioxa, a new topical drug that arrests sight-threatening disease, has met FDA requirements and is anticipated to replace Photrexa, with a manageable reimbursement process expected.
- In the most recent quarter, Glaukos reported $45 million in iDose revenue, reflecting good sequential growth despite a deceleration from prior quarters. The company is also encouraged by recent constructive dialogue with the FDA regarding the PDUFA date for iDose readministration.
- GKOS has invested $800 million in R&D since 2018, yielding 12 commercially available products and 13 in various phases of development, contributing to over 30% market growth in the most recent quarter and a 20% CAGR over the past 10 years.
- The company is focused on transforming glaucoma treatment with iDose TR, which demonstrated 81% of patients off all medications at one year in Phase 3 trials, and is developing next-generation products like iDose TREX, targeting six years of therapy.
- GKOS is launching Epioxa for keratoconus, strategically discontinuing Photrexa, and anticipates a "hand-to-hand combat" approach for reimbursement with commercial payers, a process different from iDose.
- The company is exiting the year with iDose on a $180-$190 million run rate and aims for continued model leverage and cash flow break-even in the midterm, while reinvesting in its pipeline and the Epioxa launch.
- Glaukos emphasizes its innovation-driven strategy, having invested $800 million in R&D since 2018, leading to 12 commercial products and 13 in development, and has achieved over 20% CAGR for the past decade.
- The company is focused on two key areas: interventional glaucoma with products like iDose TR, which has demonstrated sustained efficacy and is awaiting a PDUFA date for repeat administration at the end of January 2026, and iStent Infinite, targeting an expanded claim by the end of 2027.
- Glaukos is also building a new market in interventional keratoconus with Epioxa, an oxygen-infused topical drug, with a J-code targeted for July 2027 to increase patient access.
- Financially, Glaukos expects continued leverage in 2026 and aims for midterm profitability, with a near-term focus on cash flow break-even and generation, while continuing significant investments in product launches and its pipeline.
Quarterly earnings call transcripts for GLAUKOS.
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