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Rock Springs Capital Management LP

CIK:0001595725
Hedge Fund
$6B AUM
93 holdings
Baltimore, MD, United States
Founded:2013
20 employees
Latest filing:Jun 30, 2025

Rock Springs Capital Management LP is a Baltimore, Maryland-based hedge fund focused on investing primarily in healthcare and life sciences sectors. Founded in 2013, the firm manages several hedge funds including the flagship Rock Springs Capital Master Fund LP, and serves institutional and high-net-worth clients. With about 20 employees, Rock Springs Capital is recognized for its deep expertise in healthcare-sector investing.

Investment Strategy

Rock Springs Capital Management LP pursues a fundamental, research-driven investment strategy with a primary focus on healthcare and life sciences. The firm employs a long/short equity approach, leveraging specialized healthcare knowledge and bottom-up research to identify attractive investment opportunities within biopharmaceuticals, medical technology, and healthcare services. Risk management and portfolio diversification are hallmarks of their disciplined methodology.

Top Buys
A
AGIOAGIOS PHARMACEUTICALS INC
+$22.9M
C
CAICARIS LIFE SCIENCES INC
+$21.2M
O
OMDAOMADA HEALTH INC
+$16.8M
M
MRUSMERUS N V
+$14.7M
I
INSMINSMED INC
+$13.5M
Top Sells
B
BPMCBLUEPRINT MEDICINES CORP
-$65.4M
U
UNHUNITEDHEALTH GROUP INC
-$36.9M
T
TVTXTRAVERE THERAPEUTICS INC
-$24.1M
N
NUVLNUVALENT INC
-$23.2M
N
NBIXNEUROCRINE BIOSCIENCES INC
-$19.7M

Top Holdings

A
ARGXARGENX SE
+6.0%$96.9M
L
LLYELI LILLY & CO
+5.7%$90.8M
M
MRUSMERUS N V
+3.5%$55.9M
R
RYTMRHYTHM PHARMACEUTICALS INC
+3.4%$54.4M
I
INSMINSMED INC
+3.3%$52.8M

Equity Positions (91)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
A
ARGX
ARGENX SE6.04%$96.9M175,750$160.41$551.22-$7.1M
L
LLY
ELI LILLY & CO5.66%$90.8M116,500$714.25$779.53-$2.9M
M
MRUS
MERUS N V3.49%$55.9M1,063,608$32.75$52.60+$14.7M
R
RYTM
RHYTHM PHARMACEUTICALS INC3.39%$54.4M861,153$18.96$63.19+$10.2M
I
INSM
INSMED INC3.29%$52.8M525,000$66.93$100.64+$13.5M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+51.5%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+16.7%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+9.5%
ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES
+3.4%
SERVICES-MEDICAL LABORATORIES
+3.2%