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Rock Springs Capital Management LP

CIK:0001595725
Hedge Fund
$6B AUM
93 holdings
Baltimore, MD, United States
Founded:2013
20 employees
Latest filing:Jun 30, 2025

Rock Springs Capital Management LP is a Baltimore, Maryland-based hedge fund focused on investing primarily in healthcare and life sciences sectors. Founded in 2013, the firm manages several hedge funds including the flagship Rock Springs Capital Master Fund LP, and serves institutional and high-net-worth clients. With about 20 employees, Rock Springs Capital is recognized for its deep expertise in healthcare-sector investing.

Investment Strategy

Rock Springs Capital Management LP pursues a fundamental, research-driven investment strategy with a primary focus on healthcare and life sciences. The firm employs a long/short equity approach, leveraging specialized healthcare knowledge and bottom-up research to identify attractive investment opportunities within biopharmaceuticals, medical technology, and healthcare services. Risk management and portfolio diversification are hallmarks of their disciplined methodology.

Latest 13F Filing Activity

Rock Springs Capital Management LP filed their most recent 13F report on Jun 30, 2025 disclosing 91 equity positions with a total 13F market value of $2B. The fund increased holdings in Agios Pharmaceuticals Inc., Caris Life Sciences Inc., Omada Health Inc. among other positions. Rock Springs Capital Management LP reduced exposure to Blueprint Medicines Corp., Unitedhealth Group Inc., Travere Therapeutics Inc. among others.

Top Buys
A
AGIOAGIOS PHARMACEUTICALS INC
+$22.9M
C
CAICARIS LIFE SCIENCES INC
+$21.2M
O
OMDAOMADA HEALTH INC
+$16.8M
M
MRUSMERUS N V
+$14.7M
I
INSMINSMED INC
+$13.5M
Top Sells
B
BPMCBLUEPRINT MEDICINES CORP
-$65.4M
U
UNHUNITEDHEALTH GROUP INC
-$36.9M
T
TVTXTRAVERE THERAPEUTICS INC
-$24.1M
N
NUVLNUVALENT INC
-$23.2M
N
NBIXNEUROCRINE BIOSCIENCES INC
-$19.7M

Top Holdings

A
ARGXARGENX SE
+6.0%$96.9M
L
LLYELI LILLY & CO
+5.7%$90.8M
M
MRUSMERUS N V
+3.5%$55.9M
R
RYTMRHYTHM PHARMACEUTICALS INC
+3.4%$54.4M
I
INSMINSMED INC
+3.3%$52.8M

Equity Positions (91)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
ARGENX SE6.04%$96.9M175,750$160.41$551.22-$7.1M
ELI LILLY & CO5.66%$90.8M116,500$714.25$779.53-$2.9M
MERUS N V3.49%$55.9M1,063,608$32.75$52.60+$14.7M
RHYTHM PHARMACEUTICALS INC3.39%$54.4M861,153$18.96$63.19+$10.2M
INSMED INC3.29%$52.8M525,000$66.93$100.64+$13.5M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+51.5%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+16.7%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+9.5%
ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES
+3.4%
SERVICES-MEDICAL LABORATORIES
+3.2%

Investment Team (2)

NameRoleLocationLinkedIn
B
Bigyan Bista
AnalystWashington, DC , United States
D
Dan S.
AnalystMD , United States