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Samsara Biocapital, LLC

CIK:0001744967
Venture Capital
$2B AUM
29 holdings
Palo Alto, CA, USA
Founded:2016
25 employees
Latest filing:Jun 30, 2025

Samsara BioCapital is a venture capital firm focused on healthcare and biotechnology investments.

Investment Strategy

Venture capital investments in healthcare and biotechnology companies

Latest 13F Filing Activity

Samsara Biocapital, LLC filed their most recent 13F report on Jun 30, 2025 disclosing 29 equity positions with a total 13F market value of $489M. The fund increased holdings in Scholar Rock HLDG Corp., Septerna Inc., Aura Biosciences Inc. among other positions. Samsara Biocapital, LLC reduced exposure to Kalaris Therapeutics Inc., Mineralys Therapeutics Inc., Palvella Therapeutics Inc. Ne among others.

Top Buys
S
SRRKSCHOLAR ROCK HLDG CORP
+$18.4M
S
SEPNSEPTERNA INC
+$15.1M
A
AURAAURA BIOSCIENCES INC
+$6.3M
N
NGNENEUROGENE INC
+$5.6M
J
JBIOJADE BIOSCIENCES INC
+$5.3M
Top Sells
K
KLRSKALARIS THERAPEUTICS INC
-$61.4M
M
MLYSMINERALYS THERAPEUTICS INC
-$13.3M
P
PVLAPALVELLA THERAPEUTICS INC NE
-$11.4M
S
SLRNACELYRIN INC
-$6.2M
A
ALMSALUMIS INC
-$5.7M

Top Holdings

S
SRRKSCHOLAR ROCK HLDG CORP
+40.7%$198.8M
M
MLYSMINERALYS THERAPEUTICS INC
+15.7%$76.8M
S
SEPNSEPTERNA INC
+6.8%$33.3M
K
KLRSKALARIS THERAPEUTICS INC
+6.3%$30.6M
N
NGNENEUROGENE INC
+5.3%$25.7M

Equity Positions (29)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
SCHOLAR ROCK HLDG CORP40.66%$198.8M5,612,896$10.15$35.42+$18.4M
MINERALYS THERAPEUTICS INC15.70%$76.8M5,674,916$15.43$13.53-$13.3M
SEPTERNA INC6.81%$33.3M3,149,128$20.83$10.57+$15.1M
KALARIS THERAPEUTICS INC6.25%$30.6M11,448,081$8.03$2.67-$61.4M
NEUROGENE INC5.25%$25.7M1,717,127$20.29$14.95+$5.6M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+59.9%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+31.4%

Investment Team (3)

NameRoleLocationLinkedIn
Cory Freedland
Cory Freedland
PartnerCA , United States
M
Mike Dybbs
PartnerBurlingame, CA , United States
Aditya Asokan
Aditya Asokan
Senior AssociateSan Francisco, CA , United States