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Frazier Life Sciences Management, L.P.

CIK:0001892134
Venture Capital
$3B AUM
49 holdings
Palo Alto, CA, US
Founded:2005
30 employees
Latest filing:Jun 30, 2025

Frazier Life Sciences Management, L.P. is a healthcare-focused investment firm headquartered in Palo Alto, CA, USA. It manages both venture and public investment funds targeting novel therapeutic companies. Founded in 2005, the firm specializes in company creation, early stage venture investments, and public biotech investments. The firm manages several billion dollars in assets and employs a team of professionals with deep domain expertise in life sciences, serving entrepreneurs, private and public biotech companies, and institutional investors.

Investment Strategy

Frazier Life Sciences pursues investments in therapeutics companies across all stages, with its Venture Funds focusing on the creation and early-stage private companies (over 30 companies created since 2005) and Series A/B opportunities. The Public Funds deploy capital to small- and mid-cap public biotech firms through PIPEs, CMPOs, IPOs, and open market support. The firm's approach emphasizes partnering closely with entrepreneurs and management teams to build valuable companies and advance novel therapeutics for patients. They have raised multi-billion dollar funds and invest globally in therapeutics innovation.

Top Buys
V
VRNAVERONA PHARMA PLC
+$100.5M
P
PHATPHATHOM PHARMACEUTICALS INC
+$56.2M
M
MIRMMIRUM PHARMACEUTICALS INC
+$39.7M
Z
ZLABZAI LAB LTD
+$33.1M
B
BBIOBRIDGEBIO PHARMA INC
+$32.7M
Top Sells
R
RYTMRHYTHM PHARMACEUTICALS INC
-$36.0M
S
SLNOSOLENO THERAPEUTICS INC
-$35.7M
K
KRYSKRYSTAL BIOTECH INC
-$29.5M
N
NAMSNEWAMSTERDAM PHARMA COMPANY
-$29.1M
M
MRUSMERUS N V
-$15.7M

Top Holdings

M
MIRMMIRUM PHARMACEUTICALS INC
+13.8%$345.8M
V
VRNAVERONA PHARMA PLC
+12.8%$320.1M
N
NAMSNEWAMSTERDAM PHARMA COMPANY
+12.0%$300.8M
B
BBIOBRIDGEBIO PHARMA INC
+6.6%$164.1M
A
ARQTARCUTIS BIOTHERAPEUTICS INC
+5.5%$138.4M

Equity Positions (48)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
M
MIRM
MIRUM PHARMACEUTICALS INC13.83%$345.8M6,795,121$26.20$50.89+$39.7M
V
VRNA
VERONA PHARMA PLC12.80%$320.1M3,383,950$15.98$94.58+$100.5M
N
NAMS
NEWAMSTERDAM PHARMA COMPANY12.03%$300.8M16,607,074$14.20$18.11-$29.1M
B
BBIO
BRIDGEBIO PHARMA INC6.56%$164.1M3,800,457$21.95$43.18+$32.7M
A
ARQT
ARCUTIS BIOTHERAPEUTICS INC5.54%$138.4M9,874,511$18.53$14.02+$1.0M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+83.6%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+15.6%
BLANK CHECKS
+3.5%