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Avadel Pharmaceuticals plc is a biopharmaceutical company headquartered in Dublin, Ireland, with operations in the United States. The company specializes in developing and commercializing innovative medicines for chronic conditions. Its primary product is LUMRYZ, an extended-release formulation of sodium oxybate, designed for the treatment of cataplexy or excessive daytime sleepiness (EDS) in adults with narcolepsy.
- LUMRYZ - Provides a once-at-bedtime treatment for cataplexy or excessive daytime sleepiness (EDS) in adults with narcolepsy. Approved by the FDA in May 2023, it is the company's sole commercialized product and benefits from Orphan Drug Exclusivity until May 2030.
| Name | Position | External Roles | Short Bio | |
|---|---|---|---|---|
Gregory J. Divis ExecutiveBoard | Chief Executive Officer and Director | None | Gregory J. Divis joined Avadel in January 2017, became COO in March 2018, and CEO in June 2019. He has over 25 years of pharmaceutical industry experience. | View Report → |
Jerad G. Seurer Executive | General Counsel and Corporate Secretary | None | Jerad G. Seurer joined Avadel in October 2017 and became General Counsel in September 2020. | |
Richard J. Kim Executive | Chief Commercial Officer | None | Richard J. Kim joined Avadel in February 2021, overseeing commercial strategy and execution. | |
Thomas S. McHugh Executive | Chief Financial Officer | None | Thomas S. McHugh has been CFO since December 2019, overseeing financial operations and compliance. | |
Geoffrey M. Glass Board | Chair of the Board of Directors | CEO of Kiniciti, LLC; Chairman of Ncardia and Abzena; Operating Partner at LongueVue Capital | Geoffrey M. Glass joined the Board in July 2018 and became Chair in December 2018. He has extensive management and financial expertise. | |
Linda S. Palczuk Board | Director | None | Linda S. Palczuk has been a director since July 2018, with extensive pharmaceutical management experience. | |
Mark A. McCamish, M.D., Ph.D. Board | Director | CEO of IconOVir Bio, Inc.; Board Member at Rafael Holdings, Inc. and Shasqi Pharma, Inc. | Dr. McCamish has been a director since December 2019, with over 30 years of experience in life sciences. | |
Naseem S. Amin, M.D. Board | Director | CEO of Orphalan SA; Chairman of Arix Bioscience plc; Advisory Board Member at Imperial College; Chairman of OPEN-London | Dr. Amin joined the Board in May 2024, bringing 30 years of industry experience. | |
Peter J. Thornton Board | Director | President and CFO of Envetec Sustainable Technologies Limited; Non-Executive Director of Oculer Limited | Peter J. Thornton has been a director since June 2017, with financial expertise and corporate governance experience. |
- With the shift towards new to oxybate patients leading to lower persistency rates and potential impacts on net patient adds, how do you plan to address this challenge and improve persistency among these patients?
- Given the anticipated seasonality impacts and higher gross-to-net deductions in Q4, how might these factors affect your financial performance, and what strategies are in place to mitigate them?
- Considering the ongoing patent litigation with Jazz Pharmaceuticals and the potential financial implications of royalty adjustments, how are you preparing for these outcomes, and can you provide an update on the status of post-trial motions and royalty rate discussions?
- As competitors continue to grow their patient base in the narcolepsy setting and with the potential entry of orexin agonists, how do you plan to maintain and strengthen LUMRYZ's market position, particularly among narcolepsy type 2 patients?
- Despite consistent patient growth, you mentioned that new to oxybate patients require more support due to lower persistency; what specific investments and strategies are you implementing to enhance patient support and ensure long-term adherence?
| Customer | Relationship | Segment | Details |
|---|---|---|---|
Caremark LLC | Specialty Pharmacy | All | 53% of 2024 AR ($18.07M) , 44% of 2024 revenue ($74.41M) |
Accredo Health Group, Inc. | Specialty Pharmacy | All | 25% of 2024 AR ($8.52M) , 37% of 2024 revenue ($62.57M) |
Optum Frontier Therapies LLC | Specialty Pharmacy | All | 22% of 2024 AR ($7.50M) , 19% of 2024 revenue ($32.13M) |
Recent developments and announcements about AVDL.
Earnings
New Earnings (Q4 2024)
·Mar 3, 2025, 4:17 PMView full earnings summary →Avadel’s LUMRYZ shows strong momentum as expanded sales (+15%) and 200+ new prescribers fuel growth. 2025 revenue guidance of $240M–$260M signals nearly 50% YoY gain. While Q1 may see a dip from gross-to-net headwinds, management remains confident in achieving targets.
8-K Filings
8-K Filing
·6 days agoOther EventsView full 8-K filing →On March 5, 2025, the Compensation Committee approved performance-based equity grants. The CEO received 310,000 options and 52,000 restricted shares, the CFO 72,000 options and 12,600 restricted shares, and General Counsel 84,000 options and 14,700 restricted shares. Vesting is tied to specific Nasdaq price thresholds (e.g., $11 trigger).