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BIOGEN (BIIB)

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Earnings summaries and quarterly performance for BIOGEN.

Research analysts who have asked questions during BIOGEN earnings calls.

Brian Abrahams

Brian Abrahams

RBC Capital Markets

5 questions for BIIB

Also covers: ACAD, ATAI, BCRX +17 more
Michael Yee

Michael Yee

Jefferies

5 questions for BIIB

Also covers: ABBV, ALLO, AMGN +18 more
Salveen Richter

Salveen Richter

Goldman Sachs

5 questions for BIIB

Also covers: ACAD, AGIO, ALLO +20 more
Paul Matteis

Paul Matteis

Stifel

4 questions for BIIB

Also covers: ABOS, ACAD, ALKS +11 more
PN

Philip Nadeau

TD Cowen

4 questions for BIIB

Also covers: ADVM, APLS, ATRA +13 more
UR

Umer Raffat

Evercore ISI

4 questions for BIIB

Also covers: ALKS, AMGN, BHC +15 more
ES

Evan Seigerman

BMO Capital Markets

3 questions for BIIB

Also covers: ABBV, AMGN, ARVN +15 more
Jay Olson

Jay Olson

Oppenheimer & Co. Inc.

3 questions for BIIB

Also covers: ACAD, AMGN, BNTX +22 more
CS

Christopher Schott

JPMorgan Chase & Co.

2 questions for BIIB

Also covers: ABBV, AMGN, AMRX +15 more
David Amsellem

David Amsellem

Piper Sandler Companies

2 questions for BIIB

Also covers: ABBV, ALKS, AMGN +27 more
ES

Eric Schmidt

Cantor Fitzgerald & Co.

2 questions for BIIB

Also covers: ADCT, AGIO, BLUE +9 more
MG

Marc Goodman

Leerink Partners

2 questions for BIIB

Also covers: ACAD, ALDX, ALKS +14 more
Terence Flynn

Terence Flynn

Morgan Stanley

2 questions for BIIB

Also covers: ABBV, AMGN, ARVN +17 more
Geoffrey Meacham

Geoffrey Meacham

Citi

1 question for BIIB

Also covers: ABBV, BMY, GILD +6 more
Michael DiFiore

Michael DiFiore

Evercore ISI

1 question for BIIB

Also covers: AMGN, AMLX, ELAN +8 more
MM

Miles Minter

William Blair

1 question for BIIB

MM

Myles Minter

William Blair & Company

1 question for BIIB

Also covers: ALEC, ARCT, ARGX +11 more
TA

Tim Anderson

Bank of America

1 question for BIIB

Also covers: ABBV, AMLX, BMY +4 more
TA

Timothy Anderson

BofA Securities

1 question for BIIB

Also covers: ABBV, AMGN, AZN +10 more

Recent press releases and 8-K filings for BIIB.

Biogen reports Q4 2025 results
BIIB
Earnings
Guidance Update
M&A
  • Biogen delivered Q4 2025 non-GAAP EPS of $1.99 and full-year 2025 EPS of $15.28, on $9.9 billion in revenue, up 2% year-over-year; growth products generated $800 million in Q4 (+6%) and $3.3 billion for the year (+9%).
  • Key brands showed robust demand: Leqembi in-market sales of $134 million in Q4 (+10% sequential; +54% YoY), Skyclarys revenue of $133 million (+30% YoY), Spinraza at $356 million, and Vumerity at $181 million in the quarter.
  • 2026 milestones include FDA decisions for Leqembi Iqlik initiation (PDUFA May 24) and Spinraza high-dose regimen (PDUFA April), Phase III litifilimab SLE readout by year-end, plus felzartamab AMR and pre-POC (BIIB122, BIIB080) data mid-year.
  • Strengthened financial position with $2.1 billion free cash flow, $4.2 billion cash and marketable securities, $2 billion net debt; recorded $222 million of IPR&D charges tied to Alcyone acquisition and BD deals with Vanqua Bio and Dayra Therapeutics.
8 hours ago
Biogen reports Q4 and full-year 2025 results
BIIB
Earnings
Guidance Update
  • Biogen delivered Q4 non-GAAP EPS of $1.99 and full-year non-GAAP EPS of $15.28, with total revenue of $9.9 billion, up 2% year-over-year.
  • Growth products generated $800 million in Q4 (up 6% y/y) and $3.3 billion for FY2025 (up 9% y/y), including Leqembi in-market sales of $134 million (+54% y/y) and Skyclarys revenue of $133 million (+30% y/y) in Q4.
  • Strong cash flow supported a $2.1 billion free cash flow in FY2025, leaving $4.2 billion in cash and marketable securities and $2 billion of net debt.
  • Key pipeline milestones include a May 24 PDUFA for Leqembi subcutaneous induction , an April PDUFA for Spinraza high-dose in the US , and phase 3 readouts for litifilimab in SLE by end-2026 and felzartamab in AMR over the next 18 months.
  • 2026 guidance targets non-GAAP EPS of $15.25–16.25 and a mid-single-digit percentage decline in total revenue, with core operating expenses expected to remain roughly flat versus 2025.
9 hours ago
Biogen reports Q4 2025 results
BIIB
Earnings
M&A
  • Biogen delivered Q4 non-GAAP EPS of $1.99 and full-year non-GAAP EPS of $15.28, with FY revenue of $9.9 billion (+2% vs. 2024) and growth products generating $3.3 billion (+9%) for the year.
  • In Q4, Leqembi in-market sales were $134 million (+10% Q/Q, +54% Y/Y), Skyclarys revenue reached $133 million (+30% Y/Y), and Spinraza sales totaled $356 million.
  • The late-stage pipeline now includes 10 Phase 3 programs, with key readouts expected end-2026 for Litifilimab in SLE, mid-2026 for felzartamab in AMR, and a PDUFA date of May 24, 2026 for Leqembi iClick initiation.
  • Strong cash generation with $2.1 billion free cash flow and $4.2 billion in cash and marketable securities at year-end; completed acquisition of Alcyone Therapeutics and collaborations with Vanqua and Deira.
9 hours ago
Biogen reports Q4 2025 results and provides 2026 guidance
BIIB
Earnings
Guidance Update
  • Fourth quarter 2025 total revenue of $2.3 billion, GAAP diluted EPS of $(0.33) and Non-GAAP diluted EPS of $1.99; full year 2025 total revenue of $9.9 billion, GAAP diluted EPS $8.79 and Non-GAAP diluted EPS $15.28
  • Growth products revenue increased 6% year-over-year in Q4, led by LEQEMBI global in-market sales of ~$134 million (up 54% yoy) with U.S. sales of ~$78 million
  • FDA Priority Review granted for LEQEMBI IQLIK subcutaneous initiation (PDUFA date May 24, 2026); Breakthrough Therapy Designation for litifilimab in cutaneous lupus, with Phase 3 systemic lupus readouts expected in Q4 2026
  • 2026 guidance: Non-GAAP diluted EPS of $15.25 to $16.25; total revenue expected to decline mid-single digit versus 2025
12 hours ago
Biogen reports Q4 2025 results
BIIB
Earnings
Guidance Update
Revenue Acceleration/Inflection
  • Q4 total revenue was $2.28 B, down 7% YoY, with GAAP diluted EPS of ($0.33) and Non-GAAP diluted EPS of $1.99.
  • Growth products generated $808 M in Q4, up 6% YoY , and $3.3 B for FY 2025, up 19% YoY.
  • FY 2026 Non-GAAP diluted EPS guidance is $15.25–$16.25.
  • Generated $0.5 B of free cash flow in Q4 and $2.1 B for FY 2025, ending with $4.2 B in cash and marketable securities and $2.0 B net debt.
  • Key pipeline milestone: U.S. PDUFA date of May 24, 2026 for subcutaneous LEQEMBI initiation, alongside advancement of multiple late-stage programs.
13 hours ago
Biogen’s litifilimab receives FDA Breakthrough Therapy designation for cutaneous lupus erythematosus
BIIB
Product Launch
  • Biogen’s investigational antibody litifilimab (BIIB059) received FDA Breakthrough Therapy Designation for cutaneous lupus erythematosus, a chronic autoimmune skin disease with no approved targeted treatments.
  • The designation is based on Phase 2 LILAC data showing litifilimab reduced CLE skin disease activity versus placebo and is intended to expedite its development and review.
  • Litifilimab is a first-in-class humanized IgG1 monoclonal antibody targeting BDCA2 on plasmacytoid dendritic cells to inhibit pro-inflammatory cytokine production.
  • Biogen is advancing the AMETHYST Phase 3 study of litifilimab, with a pivotal data readout expected in 2027.
Jan 28, 2026, 12:30 PM
Biogen forecasts Q4 2025 IPR&D charges impacting EPS
BIIB
Guidance Update
Accounting Changes
  • Biogen estimates approximately $222 million of acquired in-process R&D, upfront and milestone expense in Q4 2025.
  • This charge is expected to reduce GAAP and non-GAAP net income per diluted share by about $1.26 for the quarter.
  • The company began separately presenting IPR&D, upfront and milestone expense as a distinct line item starting Q1 2025.
  • Results for the quarter ended December 31, 2025, remain preliminary and subject to adjustment upon completion of closing procedures.
Jan 13, 2026, 10:38 PM
Biogen outlines transformation and growth strategy at JPM 2026
BIIB
Product Launch
New Projects/Investments
  • Biogen delivered $1 billion gross / $800 million net savings under its Fit for Growth program, implemented a ~15% headcount reduction, and cut Non-GAAP R&D spend by 26% over the first nine months of 2025 vs. 2023.
  • The late-stage pipeline now comprises 10 Phase 3 programs, including high-conviction registrational assets in systemic lupus erythematosus, nephrology, and Dravet syndrome, alongside an early-stage portfolio targeting Alzheimer’s, Parkinson’s, MS, and rare diseases.
  • Marketed growth products achieved ~$1.9 billion in trailing twelve-month sales, with 53% revenue growth in the first three quarters of 2025 vs. 2024; key YTD year-over-year gains include LEQEMBI ~200%, QALSODY ~200%, and ZURZUVAE ~160%.
  • 2026 marks the start of a multi-year registrational data flow, with a potential FDA decision on LEQEMBI subcutaneous autoinjector in Q2–Q3 2026, and topline readouts for both litifilimab SLE studies by year-end 2026.
Jan 12, 2026, 9:30 PM
Biogen outlines cost cuts and pipeline expansion at JPMorgan Healthcare Conference
BIIB
Product Launch
Layoffs
New Projects/Investments
  • Biogen achieved $1 billion in gross and $800 million in net cost savings and reduced headcount by 15%, restructuring from an MS-centric model to a broader therapeutic focus.
  • The company launched four new first-in-disease therapies (Alzheimer’s, Friedreich’s ataxia, postpartum depression, ALS) and now fields 10 Phase III programs with five potential new products, while cutting R&D spend by 26% vs. three years ago.
  • Core growth drivers (Leqembi, Skyclarys, Zurzuvae, Qalsody, Vumerity, Spinraza) collectively grew 53% or $1.9 billion, highlighted by EU approval of high-dose Spinraza and double-digit growth for Vumerity with exclusivity into the next decade.
  • Key 2026 catalysts include Phase III readouts of Litifilimab (SLE this year, CLE in 2027), Zorevunersen, Felzartamab and AMR, plus mid-year data for tau ASO BIIB080 and LRRK2 inhibitor BIIB122 in Parkinson’s.
Jan 12, 2026, 9:30 PM
Biogen outlines 2026 growth strategy and pipeline at JPMorgan Healthcare Conference
BIIB
Product Launch
New Projects/Investments
Revenue Acceleration/Inflection
  • Executed a cost-structure overhaul with $1 billion gross and $800 million net savings, 15% headcount reduction, and 26% lower R&D spend while advancing to 10 Phase III programs targeting five new products.
  • Diversified growth portfolio: four first-in-disease launches in Alzheimer’s, Friedreich’s ataxia, postpartum depression and ALS, alongside core drivers—Leqembi, Skyclarys, Zurzuvae, Qalsody, Vumerity and Spinraza—that grew 53% ($1.9 billion) to offset MS declines.
  • Robust late-stage pipeline with 10 Phase III studies, including 2026 readouts for Litifilimab, Zorevunersen and Felzartamab, and longer-term assets BIIB080 (tau ASO) and BIIB122 (LRRK2) poised to sustain growth into 2028–2030.
  • Strategic shift to external R&D collaborations in immunology to rebuild early-stage pipeline, and SMA franchise optimization via EU approval of high-dose Spinraza, next-gen BIIB115 and implantable delivery device.
Jan 12, 2026, 9:30 PM