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FIBROGEN (FGEN)

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Earnings summaries and quarterly performance for FIBROGEN.

Recent press releases and 8-K filings for FGEN.

FibroGen Rebrands as Kyntra Bio, Shifts Strategic Focus
FGEN
New Projects/Investments
Guidance Update
  • FibroGen, Inc. has rebranded as Kyntra Bio, effective January 7, 2026, with its common stock beginning to trade under the new Nasdaq symbol "KYNB" on January 8, 2026.
  • The rebranding reflects a sharpened focus on novel therapies in oncology and rare disease, with key assets including FG-3246, FG-3180, and roxadustat. The company has also extended its cash runway into 2028.
  • Upcoming milestones include topline results from an investigator-sponsored Phase 1b/2 study of FG-3246 in Q1 2026 and interim results from a Phase 2 monotherapy trial in the second half of 2026.
  • Roxadustat received Orphan Drug Designation from the FDA for myelodysplastic syndromes, and a pivotal Phase 3 clinical trial protocol has been submitted.
4 days ago
FibroGen's Roxadustat Receives FDA Orphan Drug Designation for Myelodysplastic Syndromes
FGEN
Product Launch
New Projects/Investments
  • FibroGen's roxadustat has been granted Orphan Drug Designation by the U.S. Food and Drug Administration (FDA) for the treatment of myelodysplastic syndromes (MDS).
  • This designation provides potential benefits, including seven years of market exclusivity in the U.S. following drug approval, exemption from certain FDA fees, and financial incentives for qualified clinical development.
  • The company is on track to file the Phase 3 protocol for roxadustat in this patient population with the FDA in the fourth quarter of 2025.
  • Roxadustat, an oral medication, demonstrated an improvement in transfusion-independence in a subset of patients with high transfusion burden in a post-hoc analysis from the Phase 3 MATTERHORN trial.
Dec 15, 2025, 12:00 PM
FibroGen Reports Q3 2025 Financial Results and Pipeline Updates
FGEN
Earnings
M&A
New Projects/Investments
  • FibroGen completed the sale of FibroGen China to AstraZeneca for approximately $220 million in Q3 2025, which included an enterprise value of $85 million and approximately $135 million of net cash held in China.
  • This transaction enabled the company to repay its term loan to Morgan Stanley Tactical Value and extend its cash runway into 2028.
  • FibroGen initiated a Phase 2 monotherapy trial for FG-3246 and FG-3180 in metastatic castration-resistant prostate cancer (mCRPC), with interim results expected in 2H 2026.
  • The company plans to submit the Phase 3 protocol in Q4 2025 for roxadustat in anemia of low-risk myelodysplastic syndromes (LR-MDS), with a potential Phase 3 initiation in 2026.
Nov 10, 2025, 10:00 PM
FibroGen Reports Q3 2025 Financials and Provides Business Update
FGEN
Earnings
Guidance Update
New Projects/Investments
  • FibroGen reported $1.1 million in total revenue for Q3 2025 and a net loss from continuing operations of $13.1 million, or $3.25 per basic and diluted share. Total operating costs and expenses significantly decreased by 86% year-over-year to $6.5 million.
  • The sale of FibroGen China in August 2025 for approximately $220 million extended the company's cash runway into 2028 and enabled the payoff of a $80.9 million term loan.
  • The company reiterated its full-year 2025 total revenue guidance of $6 million to $8 million and updated its total operating costs and expenses guidance to $50 million to $60 million, representing a 70% reduction from full-year 2024 at the midpoint.
  • FibroGen initiated a Phase 2 monotherapy trial for FG3246 in Q3 2025, with top-line results from an investigator-sponsored trial expected in Q1 2026 and interim Phase 2 results in H2 2026. For Roxadustat, the Phase 3 trial protocol for lower-risk myelodysplastic syndromes is on track for submission in Q4 2025, with a decision on independent development or partnering expected by Q2 2026.
Nov 10, 2025, 10:00 PM
FibroGen Reports Q3 2025 Financial Results and Business Updates
FGEN
Earnings
M&A
New Projects/Investments
  • FibroGen reported total revenue from continuing operations of $1.1 million and a net loss from continuing operations of $13.1 million for the third quarter of 2025.
  • The company completed the sale of FibroGen China to AstraZeneca for approximately $220 million, which included $135 million in net cash, extending its cash runway into 2028.
  • Key clinical developments include the initiation of the Phase 2 monotherapy trial of FG-3246 and an agreement with the FDA on the pivotal Phase 3 trial design for roxadustat in LR-MDS, with protocol submission anticipated in Q4 2025.
Nov 10, 2025, 9:05 PM
FibroGen Reports Q3 2025 Financial Results and Business Update
FGEN
Earnings
M&A
New Projects/Investments
  • FibroGen reported total revenue from continuing operations of $1.1 million and a net loss from continuing operations of $13.1 million for the third quarter of 2025.
  • The company completed the sale of FibroGen China to AstraZeneca for approximately $220 million, which helped simplify its capital structure.
  • As of September 30, 2025, FibroGen held $121.1 million in cash, cash equivalents, investments, and accounts receivable, extending its cash runway into 2028.
  • Key clinical developments include the initiation of the Phase 2 monotherapy trial of FG-3246 for metastatic castration-resistant prostate cancer and agreement with the FDA on design elements for the pivotal Phase 3 trial for roxadustat in lower-risk myelodysplastic syndromes.
  • Upcoming milestones include topline results for an investigator-sponsored FG-3246 study in 1Q 2026 and the anticipated Phase 3 protocol submission for roxadustat in 4Q 2025.
Nov 10, 2025, 9:02 PM
FibroBiologics Reports Third Quarter 2025 Financial Results and Provides Corporate Update
FGEN
Earnings
Guidance Update
New Projects/Investments
  • For the nine months ended September 30, 2025, FibroBiologics reported a net loss of approximately $15.4 million and held cash and cash equivalents of approximately $4.9 million.
  • The company is advancing preparations for manufacturing CYWC628 for a Phase 1/2 clinical trial in diabetic foot ulcers (DFU) patients, with trial initiation in Australia planned for the first quarter of 2026.
  • FibroBiologics is also preparing to submit Investigational New Drug (IND) applications for CYPS317 for psoriasis and CYMS101 for multiple sclerosis.
  • To optimize resource allocation, the company implemented cost-efficient measures to reduce operating expenses and prioritize near-term pipeline goals.
Oct 31, 2025, 8:30 PM
FibroGen completes sale of China subsidiary to AstraZeneca
FGEN
M&A
Guidance Update
  • FibroGen completed the sale of its China subsidiary to AstraZeneca for approximately $220 million, consisting of $85 million in enterprise value and approximately $135 million in net cash.
  • This transaction substantially strengthens FibroGen's financial position, extending its cash runway into 2028, and allowed for the repayment of an approximately $81 million term loan to Morgan Stanley Tactical Value.
  • The company remains on track to initiate the Phase 2 monotherapy trial of FG-3246 in metastatic castration-resistant prostate cancer (mCRPC) in 3Q 2025 and intends to file the Phase 3 protocol for roxadustat in anemia associated with lower-risk MDS in 4Q 2025.
Sep 2, 2025, 11:09 AM