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GSK (GSK)

GSK (GlaxoSmithKline) is a global biopharma company dedicated to advancing science, technology, and talent to address diseases worldwide. The company develops, manufactures, and commercializes a diverse range of medicines, vaccines, and over-the-counter (OTC) products. Its offerings span treatments for various diseases, including HIV, respiratory conditions, cancer, and bacterial infections, as well as vaccines for numerous illnesses.

  1. Specialty Medicines - Focuses on innovative treatments for HIV, oncology, respiratory conditions, and immunology, addressing complex and specialized medical needs.

    • HIV Medicines - Includes products developed by ViiV Healthcare for HIV treatment and prevention.
    • Respiratory/Immunology - Offers medicines for respiratory diseases and immune system disorders.
  2. General Medicines - Provides established pharmaceuticals for respiratory conditions and other common diseases.

    • Respiratory Products - Includes Trelegy Ellipta and Anoro Ellipta for respiratory care.
    • Other Pharmaceuticals - Features products like Augmentin and Lamictal for broader therapeutic use.
  3. Vaccines - Develops vaccines for diseases such as shingles, RSV, hepatitis, bacterial meningitis, and HPV infections.

    • Shingrix - A leading shingles vaccine.
    • Arexvy - A vaccine for respiratory syncytial virus (RSV).

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NamePositionExternal RolesShort Bio

Dame Emma Walmsley

ExecutiveBoard

Chief Executive Officer (CEO)

Independent Director at Microsoft, Inc.

Dame Emma Walmsley has been the CEO of GSK since April 1, 2017. Previously, she served as CEO of GSK Consumer Healthcare from March 2015 to March 2017 and joined GSK in 2010 from L'Oréal.

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Deborah Waterhouse

ExecutiveBoard

President of Global Health at GSK

Non-Executive Director of Schroders plc

Deborah Waterhouse is the President of Global Health at GSK and has been part of the GSK Leadership Team since January 2020, after joining GSK in 1996. Previously, she served as CEO of ViiV Healthcare since April 2017 and held several senior roles within GSK.

James Ford

ExecutiveBoard

Senior Vice President (SVP) and Group General Counsel, Legal and Compliance

Director of the European General Counsel Association; Director of the Association of Corporate Counsel; Co-chair of the US-based Civil Justice Reform Group

James Ford is the Senior Vice President (SVP) and Group General Counsel, Legal and Compliance at GSK, having joined the GSK Leadership Team in 2018 and expanded his responsibilities in 2021. He has been with GSK since 1995, serving in multiple senior legal roles.

Julie Brown

ExecutiveBoard

Chief Financial Officer (CFO)

Non-Executive Director and Chair of the Audit Committee at Diageo plc

Julie Brown has been serving as GSK's CFO since 1 May 2023 after being appointed on 3 April 2023. She is an Executive Director on the Board and brings extensive financial leadership experience, with an upcoming role as Non-Executive Director and Chair of the Audit Committee at Diageo plc.

Luke Miels

ExecutiveBoard

Chief Commercial Officer

Member of the Singapore Economic Development Board

Luke Miels has been the Chief Commercial Officer at GSK since 2017, overseeing the company’s commercial portfolio of medicines and vaccines. He also co-chairs the Portfolio Investment Board and serves on the ViiV Healthcare Board.

Regis Simard

ExecutiveBoard

President, Global Supply Chain

Member of the Board of ViiV Healthcare

Regis Simard has been serving as President, Global Supply Chain at GSK since 2018, overseeing the manufacturing and supply of GSK's medicines and vaccines. He began his GSK career in 2005 as a Site Director in France and advanced to Senior Vice President of Global Pharmaceuticals Manufacturing before his current role.

David Redfern

Executive

President, Corporate Development

Chairman of the Board of ViiV Healthcare Limited; Non-Executive Director of Aspen Pharmacare Holdings Limited

David Redfern joined GSK in 1994 and was appointed to the GSK Leadership Team as Chief Strategy Officer in 2008, later becoming President, Corporate Development.

Diana Conrad

Executive

Chief People Officer

Diana Conrad is the Chief People Officer at GSK and has been a member of the GSK Leadership Team since April 2019. Previously, she served in senior HR roles for Pharmaceuticals R&D and Consumer Healthcare, playing key roles in transforming HR strategies.

Phil Thomson

Executive

President, Global Affairs

Phil Thomson has served as President, Global Affairs at GSK since 2017, where he drives strategic stakeholder engagement and policy development. Previously, he was Senior Vice President, Communications and Government Affairs, and he began his career at Glaxo Wellcome in 1996.

Sally Jackson

Executive

Senior Vice President (SVP), Global Communications and CEO Office

Sally Jackson is the Senior Vice President (SVP), Global Communications and CEO Office at GSK, where she leads global communications and government affairs and serves as the CEO's Chief of Staff. She has been with GSK since 2001 and joined the GSK Leadership Team in March 2019, marking a significant ascent in her career at the company.

Shobie Ramakrishnan

Executive

Chief Digital and Technology Officer

Non-Executive Director at Deliveroo

Chief Digital and Technology Officer at GSK since 2021, instrumental in driving digital transformation; previously, led Digital and Technology for GSK’s Global Commercial Organisation from 2018 to 2021.

Tony Wood

Executive

Chief Scientific Officer (CSO)

Tony Wood has been the Chief Scientific Officer at GSK since August 1, 2022. He joined GSK in 2017 as Senior Vice President, Medicinal Science and Technology and previously led drug discovery and development at Pfizer.

Charles Bancroft

Board

Senior Independent Non-Executive Director

Board Member at Kodiak Sciences Inc; Board Member at BioVector Inc; Advisory Board Member at Drexel University’s LeBow College of Business

Charles Bancroft is a Senior Independent Non-Executive Director at GSK since July 18, 2022 and chairs the Audit & Risk Committee; he previously served in senior financial roles at Bristol Myers Squibb including CFO and other executive positions.

Dr Anne Beal

Board

Independent Non-Executive Director

Dr. Anne Beal is an Independent Non-Executive Director and Chair of the Corporate Responsibility Committee at GSK, bringing extensive experience as a physician, entrepreneur, and health policy expert. She is known for her work in patient advocacy and driving GSK's ESG initiatives.

Dr Gavin Screaton

Board

Non-Executive Director

Head of Medical Sciences Division at the University of Oxford; Non-Executive Director of Oxford University Hospitals NHS Foundation Trust; Trustee of the Jenner Vaccine Foundation; Co-founder of RQ Bio

Dr. Gavin Screaton joined GSK as a Non-Executive Director on 1 May 2025 and serves on both the GSK Board Science Committee and the Corporate Responsibility Committee. Previously, he held roles including Head of Medical Sciences Division at the University of Oxford, Non-Executive Director of Oxford University Hospitals NHS Foundation Trust, Trustee of the Jenner Vaccine Foundation, and Co-founder of RQ Bio.

Dr Hal Barron

Board

Non-Executive Director

CEO and Board Co-Chair at Altos Labs Inc; Associate Adjunct Professor in Epidemiology & Biostatistics at the University of California, San Francisco

Dr Hal Barron served as Chief Scientific Officer and President, R&D starting April 1, 2018 before transitioning to his current role as Non-Executive Director on August 1, 2022. He has vast biosciences experience, having held senior roles at Calico LLC, Roche, and Genentech.

Dr Harry (Hal) Dietz

Board

Independent Non-Executive Director

Non-Executive Board Director at the Altius Institute for Biomedical Sciences

Dr. Harry (Hal) Dietz is an Independent Non-Executive Director at GSK, appointed on 1 January 2022. He is a world-leading expert in human genetics with significant contributions in the field of Marfan Syndrome and the development of novel therapies.

Dr Jeannie Lee

Board

Independent Non-Executive Director

Professor of Genetics and Pathology at Harvard Medical School; Acting Chair of the Department of Molecular Biology at Massachusetts General Hospital; Scientific Advisory Board member at Skyhawk Therapeutics, Inc.

Dr Jeannie Lee is an Independent Non-Executive Director at GSK, joining the Board on March 4, 2024 and recognized as a renowned expert in RNA Biology with significant contributions in academia and biotech innovation.

Dr Vishal Sikka

Board

Independent Non-Executive Director

Board Member, Oracle Corporation; Member, Supervisory Board, BMW AG; Member of the Advisory Board of Stanford University's AI Center

Dr. Vishal Sikka serves as an Independent Non-Executive Director at GSK since July 18, 2022. He brings deep expertise in AI, ML, and cybersecurity with prior leadership roles as CEO of Infosys and Founder of Vianai Systems.

Elizabeth McKee Anderson

Board

Independent Non-Executive Director

Board Member at BioMarin

Elizabeth McKee Anderson has served as the Independent Non-Executive Director at GSK since 1 September 2022. She brings extensive experience from her roles in commercial biopharmaceuticals at Janssen Pharmaceuticals and Wyeth Vaccines, and she contributes valuable expertise through her board participation at BioMarin.

Sir Jonathan Symonds

Board

Non-Executive Chair

Non-Executive Chair of Energy Aspects; Member of the European Round Table for Industry; Senior Advisor to Chatham House

Sir Jonathan Symonds, a seasoned finance and life sciences expert, has served as GSK's Non-Executive Chair since 1 September 2019. Previously, he held roles such as Independent Non-Executive Director at HSBC and CFO positions at Novartis and AstraZeneca.

Wendy Becker

Board

Independent Non-Executive Director

Chair of Logitech International S.A.; Board Member and Chair of the Compensation Committee at Sony Group Corporation; Senior Independent Director and Chair of the Remuneration Committee at Oxford Nanopore Technologies plc; Member of the governing bodies of the University of Oxford

Wendy Becker has served as an Independent Non-Executive Director at GSK since October 1, 2023, and brings extensive experience from leadership roles including CEO at Jack Wills Limited and Group Chief Marketing Officer at Vodafone Group plc. She has also contributed to governance through board roles with organizations such as Cancer Research UK and NHS England.

  1. Given the extended PDUFA date for BLENREP and evolving regulatory feedback from the FDA, how does management plan to mitigate potential delays in U.S. approval and what quantitative impact might this have on the 2028 and 2031 financial outlook?
  2. With anticipated U.S. tariffs and noted supply chain optimization charges affecting gross margins, can you provide more detailed insights on the expected margin accretion in the second half of 2025 and your specific mitigation strategies?
  3. In light of the revised timelines and recruitment challenges noted in the Camlopixant phase III studies, what specific adjustments are being implemented to ensure robust U.S. enrollment and timely data readouts without compromising patient safety?
  4. Considering the recent BD deals, such as the Hengrui collaboration and acquisition of IDRX, how does management balance increased R&D investments with strategic acquisitions to sustain pipeline growth, and what are the key criteria for evaluating these opportunities?
  5. With ongoing discussions around MFN and DTC cash pay options in the U.S., how does management plan to adapt pricing and market access strategies in critical segments like anti-infectives and HIV, and what timelines do you foresee for these initiatives?

Notable M&A activity and strategic investments in the past 3 years.

CompanyYearDetails

Sierra Oncology, Inc.

2022

The acquisition was completed for approximately $1.9 billion in cash at $55 per share, adding momelotinib to address myelofibrosis and strengthening GSK’s oncology portfolio.

BELLUS Health Inc.

2023

Completed on 28 June 2023, this acquisition for US$2.0 billion (at a premium of about 100%) delivers camlipixant, a phase III asset for treating refractory chronic cough, with expected regulatory approval and launch in 2026.

Affinivax Inc.

2023

The deal integrated Affinivax’s innovative MAPS platform and next‐generation pneumococcal vaccine candidates into GSK’s portfolio, with significant restructuring and contingent consideration costs recorded.

Aiolos Bio, Inc.

2024

Completed with an upfront payment of $1 billion plus up to $400 million in success-based milestones, this acquisition expands GSK’s respiratory pipeline with AIO-001, a phase II-ready antibody targeting the TSLP pathway.

Elsie Biotechnologies

2024

This completed acquisition for up to US$51 million provides access to advanced oligonucleotide therapeutics and complementary P(V) chemistry technologies, boosting GSK’s drug discovery platform.

Efimosfermin

2025

The acquisition of Efimosfermin alfa—valued up to $2 billion with $1.2 billion upfront and potential for $800 million in milestone payments—expands GSK’s hepatology pipeline by targeting steatotic liver disease.

Cellphenomics GmbH

2025

Completed in 2025 for up to €44 million, this deal brings proprietary capabilities in creating durable organoid models from Berlin, enhancing GSK’s research and development capabilities.

IDRx, Inc.

2025

The acquisition, completed with a total consideration of $1.15 billion (including $1 billion upfront plus additional milestone payments), adds IDRX-42—a selective TKI for gastrointestinal stromal tumors—strengthening GSK's oncology portfolio.

Recent press releases and 8-K filings for GSK.

GSK plc Announces Share Buyback on October 2, 2025
·$GSK
Share Buyback
  • GSK plc purchased an aggregate of 335,000 of its ordinary shares on October 2, 2025, as part of its existing buyback programme.
  • The shares were acquired at prices ranging from a lowest price of 1,638.50p to a highest price of 1,683.00p per share, with a volume-weighted average price of 1,655.37p.
  • Following this purchase, GSK plc holds 248,366,844 ordinary shares in treasury, representing 6.11% of the total voting rights.
  • Since September 30, 2025, the company has purchased a total of 902,000 ordinary shares.
2 days ago
GSK plc announces share buyback on October 1, 2025
·$GSK
Share Buyback
  • GSK plc purchased 262,000 ordinary shares on October 1, 2025, through BNP Paribas SA, as part of its existing buyback programme.
  • The volume-weighted average price paid per share was 1,626.49p, with prices ranging from a low of 1,594.50p to a high of 1,670.00p.
  • Since September 30, 2025, the company has purchased a total of 567,000 ordinary shares.
  • Following this purchase, GSK plc will hold 248,031,844 ordinary shares in treasury, representing 6.10% of the total voting rights.
3 days ago
GSK plc Announces Share Buyback on September 30, 2025
·$GSK
Share Buyback
  • GSK plc purchased 305,000 of its ordinary shares on 30 September 2025 through BNP Paribas SA, as part of its existing buyback programme.
  • The shares were acquired at prices ranging from a lowest of 1,521.00p to a highest of 1,591.00p, with a volume-weighted average price of 1,548.83p.
  • These purchased shares will be held as Treasury shares.
  • Following this transaction, the company holds 247,769,844 ordinary shares in treasury, which represents 6.09% of the total voting rights.
4 days ago
GSK Announces Third Tranche of Share Buyback Programme
·$GSK
Share Buyback
Guidance Update
  • GSK plc announced the third tranche of its £2 billion share buyback programme on September 30, 2025.
  • This tranche is for up to £0.3 billion and is expected to commence on September 30, 2025, with completion anticipated by December 19, 2025.
  • The programme's purpose is to return excess capital to shareholders, reduce share capital, and is expected to enhance earnings per share.
5 days ago
GSK plc appoints Luke Miels as CEO Designate
·$GSK
CEO Change
Management Change
Executive Compensation
  • GSK plc has appointed Luke Miels as CEO Designate, who will assume full responsibilities as CEO and join the Board on January 1, 2026.
  • Miels, currently Chief Commercial Officer, has been instrumental in building GSK's specialty medicines portfolio.
  • He will succeed Dame Emma Walmsley, who will step down from the Board on December 31, 2025, and remain with the company until September 30, 2026, to support an orderly transition.
  • Luke Miels' starting base salary will be £1,375,000, with an on-target annual bonus of 150% and a 2026 Long Term Incentives grant of 7.25x salary.
  • The company has set a target for total sales of more than £40 billion by 2031, with 2026 marking a pivotal new phase to deliver these outlooks under the new leadership.
6 days ago
GSK Announces CEO Transition
·$GSK
CEO Change
Management Change
Executive Compensation
  • Emma Walmsley will step down as CEO of GSK at the end of 2025, with her notice period concluding on September 30, 2026.
  • Luke Miels, GSK's current chief commercial officer, will succeed Walmsley as CEO starting January 1, 2026.
  • Walmsley is recognized for transforming GSK, including overseeing the demerger of its consumer healthcare business, Haleon, and strengthening its biopharma portfolio.
  • Miels, who joined GSK in 2017, has extensive global biopharma experience and has been responsible for building GSK's drug portfolio, notably in oncology.
  • Walmsley's total compensation in the previous year was £10.6 million, down from £12.7 million in 2023.
6 days ago
GSK Updates on Full-Year Guidance, Pipeline Progress, and R&D Investment
·$GSK
Guidance Update
Product Launch
New Projects/Investments
  • GSK has upgraded its full-year guidance to the top end of the range and maintains its long-term sales guidance of more than $40 billion by 2031, noting a $6 billion gap between company guidance and current consensus, largely due to oncology assets like Blenrep.
  • The company expects five major approvals and four launches this year, with key upcoming events including the October 23 PDUFA date for Blenrep and the anticipated December approval for Depemokimab. Blenrep is projected to achieve more than $3 billion in sales.
  • R&D spending is set to grow at a higher rate than sales to expedite pipeline development.
  • Significant growth opportunities are identified in Shingrix, particularly outside the U.S. and in China, and in the HIV business with new long-acting solutions.
Sep 24, 2025, 8:00 AM
GSK Directors Purchase Company Shares
·$GSK
  • On September 19, 2025, several directors of GSK plc purchased company shares or American Depositary Shares (ADSs).
  • Charles Bancroft, Senior Independent Non-Executive Director, purchased 1,880 ADSs at $40.7387 per ADS on the New York Stock Exchange.
  • Wendy Becker, an Independent Non-Executive Director, purchased 526 Ordinary Shares at £15.0300 per share on the London Stock Exchange.
  • Other directors, including Elizabeth (Liz) McKee Anderson, Dr Hal Barron, Dr Anne Beal, Dr Hal Dietz, Dr Jeannie Lee, and Dr Vishal Sikka, also purchased ADSs at $40.7387 each on the New York Stock Exchange, with individual volumes ranging from 239 to 827 ADSs.
Sep 22, 2025, 4:17 PM
GSK plc announces share buyback on September 17, 2025
·$GSK
Share Buyback
  • GSK plc purchased 209,886 of its ordinary shares on September 17, 2025, as part of its existing buyback programme.
  • The shares were acquired at prices ranging from a lowest price of 1,461.50p to a highest price of 1,478.50p, with a volume-weighted average price of 1,471.87p.
  • Following this purchase, GSK plc holds 247,448,986 ordinary shares in treasury, representing 6.08% of the total voting rights.
  • Since the buyback programme began on June 4, 2025, the company has purchased a total of 29,314,603 ordinary shares.
Sep 18, 2025, 11:17 AM
GSK announces $30 billion U.S. investment in R&D and manufacturing
·$GSK
New Projects/Investments
Hiring
  • GSK plc plans to invest $30 billion in research and development (R&D) and supply chain infrastructure in the United States over the next five years.
  • This includes a new $1.2 billion investment in advanced manufacturing facilities, AI, and advanced digital technologies, which is expected to create hundreds of highly skilled U.S. jobs.
  • The $1.2 billion investment specifically covers the construction of an additional new biologics flex factory in Upper Merion, Pennsylvania, with construction planned to commence in 2026, and new AI and advanced digital technology capabilities across GSK's existing five U.S. manufacturing sites.
  • Over the last 12 months, GSK has committed approximately $2 billion to U.S. manufacturing, including an $800 million facility at Marietta, Pennsylvania, which began construction in October 2024.
Sep 17, 2025, 10:59 AM