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Highvista Strategies LLC

CIK:0001335325
Asset Manager
$11B AUM
146 holdings
Boston, MA, United States
Founded:2004
75 employees
Latest filing:Jun 30, 2025

HighVista Strategies LLC is an employee-owned specialty alternative asset manager headquartered in Boston, Massachusetts. Founded in 2004, the firm specializes in delivering alpha-driven investment strategies through structurally inefficient markets. HighVista manages over $11 billion for a global clientele of sophisticated investors, including institutions and high-net-worth individuals. The firm's team comprises more than 75 employees, blending deep expertise in private equity, venture capital, private credit, and public markets. HighVista is known for its rigorous discipline, inquisitive thinking, and its partner-owned structure, serving clients seeking differentiated returns beyond conventional approaches.

Investment Strategy

HighVista Strategies pursues alpha generation by investing in 'beautifully inefficient markets,' which are structurally less competitive and require specialized knowledge to access. The firm offers multi-asset alternative strategies together with targeted solutions in private credit, lower middle-market private equity, early-stage venture capital, and public market investments such as biotechnology equities and hedged equity strategies. HighVista’s approach is characterized by deep specialization, strategic concentration, and a disciplined investment process. The firm constructs diversified yet focused portfolios by partnering with specialized managers, emphasizing sectors where inefficiency creates outsize opportunities for return.

Top Buys
V
VRDNVIRIDIAN THERAPEUTICS INC
+$4.3M
M
MRUSMERUS N V
+$2.4M
A
AKROAKERO THERAPEUTICS INC
+$2.2M
A
AMDADVANCED MICRO DEVICES INC
+$2.2M
C
CLDXCELLDEX THERAPEUTICS INC NEW
+$2.2M
Top Sells
A
ACIALBERTSONS COS INC
-$4.2M
S
SWTXSPRINGWORKS THERAPEUTICS INC
-$3.0M
G
GOOGALPHABET INC
-$2.1M
B
BHCBAUSCH HEALTH COS INC
-$2.0M
G
GEHCGE HEALTHCARE TECHNOLOGIES I
-$1.9M

Top Holdings

D
DBCINVESCO DB COMMDY INDX TRCK
+11.5%$31.3M
V
VRDNVIRIDIAN THERAPEUTICS INC
+2.5%$6.8M
A
ANSSANSYS INC
+2.2%$6.0M
M
MSFTMICROSOFT CORP
+1.9%$5.1M
M
MRUSMERUS N V
+1.7%$4.7M

Equity Positions (145)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
D
DBC
INVESCO DB COMMDY INDX TRCK11.51%$31.3M1,436,136$22.46$21.81-$990.9K
V
VRDN
VIRIDIAN THERAPEUTICS INC2.49%$6.8M484,559$16.17$13.98+$4.3M
A
ANSS
ANSYS INC2.21%$6.0M17,100$348.42$351.22+$2.0M
M
MSFT
MICROSOFT CORP1.88%$5.1M10,258$367.55$497.41+$1.4M
M
MRUS
MERUS N V1.74%$4.7M89,762$34.19$52.60+$2.4M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+24.9%
COMMODITY CONTRACTS BROKERS & DEALERS
+11.5%
SERVICES-PREPACKAGED SOFTWARE
+8.9%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+5.4%
COMPUTER STORAGE DEVICES
+3.7%