Braidwell LP
Braidwell LP is a Delaware-based hedge fund founded in 2021 by Alex Karnal and Brian Kreiter, with headquarters in Stamford, Connecticut. The firm focuses on investing in the healthcare sector, leveraging deep industry expertise. Braidwell LP manages over $5 billion in assets and employs around 38 professionals, most of whom are investment experts. The firm primarily serves institutional clients and high-net-worth individuals, aiming to generate value through fundamental research and life sciences sector specialization.
Investment Strategy
Braidwell LP employs a fundamental, research-driven investment approach focused predominantly on the healthcare and life sciences sectors. The firm identifies investment opportunities by leveraging sector expertise, seeking alpha through in-depth company analysis, and taking both long and short positions. Braidwell invests across the capital structure, including public equities and private investments, with a goal to capture growth and innovation in healthcare, biotechnology, and related fields. The strategy is designed to deliver risk-adjusted returns by capitalizing on transformative trends and scientific advancements within healthcare.
Latest 13F Filing Activity
Braidwell LP filed their most recent 13F report on Jun 30, 2025 disclosing 45 equity positions with a total 13F market value of $3B. The fund increased holdings in Caris Life Sciences Inc., Nuvalent Inc., Krystal Biotech Inc. among other positions. Braidwell LP reduced exposure to Blueprint Medicines Corp., Bicara Therapeutics Inc., Transmedics Group Inc. among others.
Top Holdings
Equity Positions (45)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
C CAI | CARIS LIFE SCIENCES INC | 6.69% | $195.5M | 7,316,142 | $26.72 | $26.72 | +$195.5M |
N NBIX | NEUROCRINE BIOSCIENCES INC | 4.99% | $145.9M | 1,160,425 | $106.29 | $125.69 | +$14.0M |
X XENE | XENON PHARMACEUTICALS INC | 3.86% | $112.8M | 3,605,029 | $36.31 | $31.30 | +$21.9M |
A ARGX | ARGENX SE | 3.67% | $107.2M | 194,491 | $499.16 | $551.22 | +$12.0M |
K KRYS | KRYSTAL BIOTECH INC | 3.42% | $100.0M | 727,811 | $149.27 | $137.46 | +$27.8M |
Industry Allocation
Investment Team (17)
| Name | Role | Location | |
|---|---|---|---|
 | Partner, Head of Trading | New York, NY , United States | |
 | Associate | Stamford, CT , United States | |
 | Partner | New York, NY , United States | |
I Ilan Sender | Partner | New York, NY , United States | |
 | Partner | United States | |
 | Partner | Chicago, IL , United States | |
N Narendra Nayak | Partner | New York, NY , United States | |
Z Zhenhua He | Partner | Stamford, CT , United States | |
 | Associate | Stamford, CT , United States | |
L Laura Sterner | Head of Business Development, Global Equities | New York, NY , United States |