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Casdin Capital, LLC
Casdin Capital, LLC is a New York-based hedge fund specializing in investments across the life sciences and healthcare sectors. Founded by Eli Casdin in 2011, the firm manages a team of approximately 33 employees as of 2025, with a focus on companies driving innovation in biotechnology, medical devices, diagnostics, and related technologies. Casdin Capital serves institutional investors and high-net-worth individuals, leveraging specialized expertise to identify high-growth opportunities in science-driven markets.
Investment Strategy
Casdin Capital employs a long-term fundamental investment approach focusing on life sciences, biotechnology, diagnostics, and broader healthcare innovation. The firm invests in both public and private companies, emphasizing emerging and disruptive technologies that have the potential to transform healthcare markets. Their philosophy combines deep scientific diligence with financial analysis to identify under-appreciated growth and value opportunities, typically maintaining a concentrated portfolio of high-conviction positions in companies at the forefront of medical advancements.
Latest 13F Filing Activity
Casdin Capital, LLC filed their most recent 13F report on Jun 30, 2025 disclosing 33 equity positions with a total 13F market value of $1B. The fund increased holdings in Verve Therapeutics Inc., Relay Therapeutics Inc., Illumina Inc. among other positions. Casdin Capital, LLC reduced exposure to Sarepta Therapeutics Inc., Biolife Solutions Inc., Blueprint Medicines Corp. among others.
Top Holdings
Equity Positions (33)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
W WGS | GENEDX HOLDINGS CORP | 29.48% | $323.7M | 3,507,164 | $8.51 | $92.31 | +$13.1M |
B BLFS | BIOLIFE SOLUTIONS INC | 15.12% | $166.0M | 7,707,165 | $22.13 | $21.54 | -$32.9M |
R RVMD | REVOLUTION MEDICINES INC | 9.68% | $106.2M | 2,887,933 | $28.23 | $36.79 | -$24.5M |
L LAB | STANDARD BIOTOOLS INC | 8.31% | $91.3M | 76,075,636 | $2.49 | $1.20 | +$9.1M |
I ILMN | ILLUMINA INC | 5.60% | $61.5M | 645,000 | $123.31 | $95.41 | +$14.3M |
Industry Allocation
Investment Team (8)
| Name | Role | Location | |
|---|---|---|---|
B Brad Weisgerber | Trader | Hoboken, NJ , United States | |
 | Associate | New York, NY , United States | |
 | Research Analyst | United States | |
 | Associate | New York, NY , United States | |
 | Senior Quantitative Analyst | New York, NY , United States | |
 | Research Associate | New York, NY , United States | |
 | Research Analyst | Boston, MA , United States | |
 | Associate | New York, NY , United States |
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