RTW Investments, LP
RTW Investments, LP is a New York-headquartered SEC-registered investment adviser founded in 2009. The firm specializes in investing in life sciences and biotechnology sectors, with a focus on identifying and supporting innovative companies developing transformational treatments and technologies. As of 2025, RTW employs approximately 67 professionals, nearly half of whom are investment personnel, and manages funds on behalf of institutional investors, endowments, foundations, and high-net-worth individuals.
Investment Strategy
RTW Investments, LP employs a research-driven investment approach concentrated in the life sciences, particularly biotechnology and medical devices. The firm seeks to identify breakthrough innovations in therapeutics and related technologies by leveraging deep scientific and industry expertise. Its investment strategy spans public and private markets, prioritizing companies with the potential for significant clinical and commercial impact. RTW partners actively with portfolio companies to help advance new therapies, with long-term value creation and impact in healthcare at the core of its philosophy.
Top Holdings
Equity Positions (72)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
M MDGL | MADRIGAL PHARMACEUTICALS INC | 8.59% | $603.4M | 1,993,687 | $265.29 | $302.64 | -$57.0M |
N NTRA | NATERA INC | 6.24% | $438.2M | 2,593,645 | $42.81 | $168.94 | +$71.4M |
P PTCT | PTC THERAPEUTICS INC | 5.39% | $378.3M | 7,746,415 | $38.51 | $48.84 | -$3.0M |
A ARGX | ARGENX SE | 5.29% | $371.2M | 673,497 | $352.05 | $551.22 | -$27.4M |
P PTGX | PROTAGONIST THERAPEUTICS INC | 4.53% | $318.1M | 5,756,277 | $24.30 | $55.27 | +$41.6M |