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Tri Locum Partners LP

CIK:0001826434
Hedge Fund
$753M AUM
23 holdings
New York, NY, US
Founded:2019
8 employees
Latest filing:Jun 30, 2025

Tri Locum Partners LP is a New York-based, SEC-registered hedge fund founded in 2019 by Dr. Prashanth Jayaram, a former portfolio manager at Citadel. The firm specializes in healthcare investment, targeting both public and private opportunities globally. It offers discretionary investment management to qualified clients through private investment vehicles, and currently manages approximately $753 million in assets. As of April 2025, the firm employs 8 staff, primarily serving institutional investors in the financial services sector.

Investment Strategy

Tri Locum Partners deploys a market-neutral long/short equity strategy focused exclusively on healthcare sectors such as biotechnology, pharmaceuticals, medical devices, and services. Their approach blends deep fundamental, science-based research with proprietary portfolio construction and risk management techniques. This aims to generate superior idiosyncratic returns, with high concentration and minimized exposure to macroeconomic and market risks, targeting consistent risk-adjusted performance in all cycles.

Top Buys
A
ALNYALNYLAM PHARMACEUTICALS INC
+$29.2M
V
VRNAVERONA PHARMA PLC
+$20.5M
A
ASNDASCENDIS PHARMA A/S
+$20.4M
U
UNHUNITEDHEALTH GROUP INC
+$18.9M
T
TEVATEVA PHARMACEUTICAL INDS LTD
+$18.0M
Top Sells
G
GILDGILEAD SCIENCES INC
-$10.0M
I
ILMNILLUMINA INC
-$9.6M
I
INSMINSMED INC
-$7.8M
A
AXSMAXSOME THERAPEUTICS INC
+$4.7M
B
BPMCBLUEPRINT MEDICINES CORP
-$4.4M

Top Holdings

T
TEVATEVA PHARMACEUTICAL INDS LTD
+10.4%$34.3M
M
MDGLMADRIGAL PHARMACEUTICALS INC
+9.0%$29.6M
A
ALNYALNYLAM PHARMACEUTICALS INC
+8.9%$29.2M
A
ARGXARGENX SE
+8.0%$26.3M
A
ASNDASCENDIS PHARMA A/S
+7.7%$25.5M

Equity Positions (23)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
T
TEVA
TEVA PHARMACEUTICAL INDS LTD10.41%$34.3M2,046,846$14.13$16.76+$18.0M
M
MDGL
MADRIGAL PHARMACEUTICALS INC8.98%$29.6M97,765$285.05$302.64+$17.0M
A
ALNY
ALNYLAM PHARMACEUTICALS INC8.86%$29.2M89,525$326.09$326.09+$29.2M
A
ARGX
ARGENX SE8.00%$26.3M47,793$508.31$551.22+$15.8M
A
ASND
ASCENDIS PHARMA A/S7.73%$25.5M147,642$168.93$172.60+$20.4M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+69.0%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+10.2%
ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS
+7.3%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+5.9%
HOSPITAL & MEDICAL SERVICE PLANS
+5.7%