Research analysts who have asked questions during GENMAB earnings calls.
Asthika Goonewardene
Truist Securities
4 questions for GMAB
Yaron Werber
TD Cowen
4 questions for GMAB
Jonathan Chang
Leerink Partners
3 questions for GMAB
Matthew Phipps
William Blair
3 questions for GMAB
Michael Schmidt
Guggenheim Securities
3 questions for GMAB
Rajan Sharma
Goldman Sachs Group, Inc.
3 questions for GMAB
Qize Ding
Redburn Atlantic
2 questions for GMAB
Vikram Purohit
Morgan Stanley
2 questions for GMAB
Xian Deng
Berenberg
2 questions for GMAB
Emily Field
Barclays
1 question for GMAB
Etzer Darout
BMO Capital Markets
1 question for GMAB
Peter Verdult
Citigroup Inc.
1 question for GMAB
Sachin Jain
Bank of America
1 question for GMAB
Suzanne van Voorthuizen
Kempen & Co
1 question for GMAB
Yifeng Liu
HSBC
1 question for GMAB
Recent press releases and 8-K filings for GMAB.
- Genmab A/S announced that worldwide net trade sales of DARZALEX® (daratumumab) in 2025 totaled USD 14,351 million.
- These sales were comprised of USD 8,266 million from the U.S. and USD 6,085 million from the rest of the world.
- Genmab receives royalties on these worldwide net sales from Johnson & Johnson.
- Genmab announced positive topline results from the Phase 3 EPCORE DLBCL-1 trial for epcoritamab monotherapy in patients with relapsed/refractory Diffuse Large B-cell Lymphoma (DLBCL).
- The trial demonstrated a statistically significant improvement in progression-free survival (PFS) (HR: 0.74 [95% CI 0.60 to 0.92]), along with improvements in complete response rate, duration of response, and time to next treatment.
- This marks the first Phase 3 study to show PFS improvement for a CD3xCD20 T-cell engaging bispecific monotherapy in relapsed or refractory DLBCL.
- However, overall survival (OS) (HR: 0.96 [95% CI 0.77 to 1.20]) did not reach statistical significance in the study.
- Genmab and AbbVie will engage global regulatory authorities to discuss next steps for epcoritamab, which is already approved in over 65 countries for certain lymphoma indications.
- Genmab announced positive topline results from the Phase 3 EPCORE DLBCL-1 trial for epcoritamab in patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL).
- The trial demonstrated a statistically significant improvement in progression-free survival (PFS) with epcoritamab monotherapy (HR: 0.74 [95% CI 0.60 to 0.92]).
- This marks the first Phase 3 study to show improved PFS for a CD3xCD20 T-cell engaging bispecific monotherapy in this patient population.
- Genmab and AbbVie will engage global regulatory authorities to discuss next steps for epcoritamab based on these results.
- Genmab announced positive topline results from the Phase 3 EPCORE DLBCL-1 trial for epcoritamab in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL).
- The trial demonstrated a statistically significant improvement in progression-free survival (PFS) (HR: 0.74 [95% CI 0.60 to 0.92]), making it the first Phase 3 study to show such improvement in this patient population with a CD3xCD20 T-cell engaging bispecific monotherapy.
- Genmab and AbbVie will engage global regulatory authorities to discuss the next steps for epcoritamab based on these results.
- Genmab is positioned for sustainable long-term growth with a diversified revenue base and a powerful late-stage pipeline, including nine medicines on the market after the acquisition of Merus.
- 2026 is anticipated to be a transformational year with up to six potential registrational data readouts for three high-impact late-stage programs: Epkinly, Rina-S, and petosemtamab, setting the stage for multiple important product launches and line extensions in 2027.
- Epkinly demonstrated phase III superiority in follicular lymphoma and has three phase III trials in diffuse large B-cell lymphoma with data expected in 2026, aiming to significantly increase its addressable patient population.
- Rina-S is designed to broaden eligibility in folate receptor alpha-targeted treatment, with encouraging anti-tumor activity in ovarian and endometrial cancers and ongoing phase III trials.
- Petosemtamab, acquired through Merus, shows compelling data in head and neck cancer, with top-line data from phase III trials expected in the second half of 2026.
- Genmab begins 2026 with a diversified revenue base from nine marketed medicines and a late-stage portfolio positioned for sustainable long-term growth into the 2030s.
- The company anticipates a catalyst-rich 2026 with up to six potential registrational data readouts for key assets: Epkinly, Rina S, and Petosemtamab, which could lead to multiple product launches and line extensions starting in 2027.
- Epkinly demonstrated phase three superiority over standard of care in follicular lymphoma and is expected to have three phase three data readouts in diffuse large B-cell lymphoma in 2026, aiming to significantly expand its addressable patient population.
- Petosemtamab, acquired through Merus, achieved a 63% response rate in combination with Pembro in first-line head and neck cancer, more than triple the standard of care, with top-line phase three data anticipated in the second half of 2026.
- Genmab is financially profitable and is strategically transforming into a fully integrated biotech, focusing on operational efficiencies and disciplined investment in high-priority programs.
- Genmab is transitioning from a royalty-based company to a fully integrated, innovation-driven biotech with a diversified revenue base from nine marketed medicines, including co-owned Epkinly and Tivdak.
- 2026 is expected to be a "catalyst-rich year" with up to six potential registrational data readouts for three high-impact late-stage assets: Epkinly, Rina S, and petosemtamab, which could lead to commercial launches starting in 2027.
- Rina S has an upgraded peak sales estimate of $2 billion , with phase 2 pivotal data anticipated in H2 2026. Petosemtamab demonstrated a 63% response rate in first-line head and neck cancer in combination with Pembro, with phase 3 top-line data also expected in H2 2026.
- The company is financially profitable and focused on driving operational efficiencies and savings, particularly in phase three trials, to free up capital for expansion opportunities.
- Genmab A/S has decided to discontinue the clinical development of acasunlimab following a portfolio review.
- This decision reflects the company's prioritization of higher-impact opportunities within its late-stage pipeline and an increasingly competitive landscape.
- Genmab will now concentrate resources on programs such as EPKINLY® (epcoritamab), petosemtamab, and rinatabart sesutecan (Rina-S®).
- The company confirmed that this decision does not impact its full-year 2025 financial guidance.
- Genmab announced the discontinuation of clinical development for acasunlimab following a portfolio review.
- This decision reflects a strategic focus on higher-impact opportunities within its late-stage pipeline, including EPKINLY® (epcoritamab), petosemtamab, and rinatabart sesutecan (Rina-S®), and the evolving competitive landscape.
- The company confirmed that this discontinuation does not impact Genmab’s full-year 2025 financial guidance.
- Genmab A/S has completed its tender offer to acquire common shares of Merus N.V. for $97 per common share in cash.
- As of December 11, 2025, 94.2% of Merus's issued and outstanding common shares were validly tendered.
- The acquisition adds petosemtamab, a late-stage asset, to Genmab's portfolio, with an anticipated launch in 2027.
- Genmab expects the transaction to be accretive to EBITDA by the end of 2029, with petosemtamab projected to achieve at least one-billion-dollar annual sales potential by 2029.
- A subsequent offering period for additional Merus shares at $97.00 per share commenced on December 12, 2025, and will expire on December 29, 2025.
Quarterly earnings call transcripts for GENMAB.
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