Andrew Cooper

Anthony Petrone

Marie Thibault

Craig Bijou

Michael Matson

Michael Petusky

Rohin Patel

David Turkaly

Joanne Wuensch

Lawrence Solow

Anthony Occhiogrosso

David Rescott

Kristen Stewart

Larry Solow

Mike Matson

- **Astria Therapeutics** has commenced patient recruitment in the European Union (EU) for its **Phase III ALPHA-ORBIT trial** of **navenibart**.  **[313143_c5dc308829a543df8a01df06a3fd0817_0]** 
- Navenibart is an investigational plasma kallikrein inhibitor monoclonal antibody being developed for the treatment of **hereditary angioedema (HAE)**, with potential dosing every **three or six months**.  **[313143_c5dc308829a543df8a01df06a3fd0817_0]** **[313143_c5dc308829a543df8a01df06a3fd0817_1]** 
- The trial, authorized by the European Medicines Agency (EMA), has activated **32 sites across ten EU countries** and aims to evaluate the efficacy and safety of navenibart in up to **135 adults and 10 adolescents** with HAE Type 1 or Type 2.  **[313143_c5dc308829a543df8a01df06a3fd0817_0]** **[313143_c5dc308829a543df8a01df06a3fd0817_1]**

Astria Therapeutics Initiates EU Patient Recruitment for ALPHA-ORBIT Phase III Trial

HAEMONETICS (HAE)