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Xeris Biopharma Holdings (XERS)

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Earnings summaries and quarterly performance for Xeris Biopharma Holdings.

Recent press releases and 8-K filings for XERS.

Xeris Biopharma Holdings, Inc. Announces Preliminary Record Q4 and Full-Year 2025 Revenue
XERS
Earnings
Guidance Update
Revenue Acceleration/Inflection
  • Xeris Biopharma Holdings, Inc. expects record total revenue for full-year 2025 of $292 million, surpassing its guidance range of $285-$290 million and reflecting 44% growth compared to the prior year.
  • Recorlev® net revenue is anticipated to be $45 million for the fourth quarter 2025 and $139 million for the full-year 2025.
  • The company delivered positive Adjusted EBITDA in every quarter of 2025.
Jan 8, 2026, 12:18 PM
Xeris anticipates record 2025 revenue
XERS
Earnings
Guidance Update
Revenue Acceleration/Inflection
  • Xeris Biopharma Holdings expects to report record full-year 2025 total revenue of $292 million, exceeding its guidance range of $285-$290 million and reflecting 44% growth compared to the prior year.
  • The company anticipates Recorlev® net revenue of $139 million for the full year 2025 and $45 million for the fourth quarter.
  • Xeris also reported Gvoke® revenue growth of over 13% compared to the prior year and achieved positive Adjusted EBITDA in every quarter of 2025.
  • Full-year 2025 financial results and the 2026 outlook are planned for release on March 2, 2026.
Jan 8, 2026, 12:00 PM
Xeris Pharmaceuticals Updates Guidance and Details Growth Strategy
XERS
Guidance Update
New Projects/Investments
Revenue Acceleration/Inflection
  • Xeris Pharmaceuticals (XERS) has raised its full-year guidance to $285 million-$290 million, representing 42% growth at the midpoint, and achieved net income for the first time last quarter.
  • The company's growth driver, Recorlev, is projected to be a billion-dollar brand by 2035 and is supported by patents extending to 2040 and orphan exclusivity until 2028.
  • To accelerate Recorlev's growth, Xeris expanded its sales force by 50% in August 2024 and plans to double it again by January 2025, aiming to target 12,000 physicians.
  • Xeris is developing XP-8121, a once-weekly injectable levothyroxine, which targets a $1 billion-$3 billion market opportunity for 3-5 million patients, with a Phase 3 trial launching in H2 2026.
  • The company has laid out a target of $750 million in revenue by 2030 from its existing product portfolio.
Dec 2, 2025, 5:30 PM
Xeris Provides Business Update at Piper Sandler Healthcare Conference
XERS
Guidance Update
Revenue Acceleration/Inflection
New Projects/Investments
  • Xeris reported strong financial performance, raising its guidance to $285 million-$290 million for 42% growth at the midpoint, and achieved net income for the first time last quarter.
  • The company is significantly expanding its commercial footprint for its growth engine, Recorlev, by doubling its sales force to target 12,000 physicians starting January 1st.
  • Recorlev is protected by four Orange Book-listed patents extending to 2040 and orphan exclusivity until 2028, supporting its projection as a billion-dollar brand by 2035.
  • Xeris's pipeline product, XP-8121, a once-weekly levothyroxine injection, targets a $1 billion-$3 billion market opportunity and is slated to begin a 1,000-patient Phase 3 trial in late H2 2026.
Dec 2, 2025, 5:30 PM
Xeris Biopharma Holdings Announces Patent Allowance for XP-8121
XERS
New Projects/Investments
Legal Proceedings
  • Xeris Biopharma Holdings, Inc. announced a Notice of Allowance from the U.S. Patent and Trademark Office (USPTO) for its XP-8121 patent application on December 1, 2025.
  • The allowed claims are specific to the XP-8121 formulation, an investigational, ready-to-use liquid designed for once-weekly subcutaneous injection to address hypothyroidism.
  • This patent is considered a key milestone in strengthening the company's intellectual property protection around this Phase 3-ready pipeline program.
Dec 1, 2025, 12:00 PM
Xeris Biopharma Reports Record Q3 2025 Results and Raises Full-Year Revenue Guidance
XERS
Earnings
Guidance Update
Revenue Acceleration/Inflection
  • Xeris Biopharma reported a record-setting Q3 2025, with total product revenue exceeding $74 million, representing a 40% increase year over year.
  • The company raised the lower end of its full-year 2025 total revenue guidance to a range of $285-$290 million, which signifies a 42% increase at the midpoint compared to 2024.
  • Recorlev revenue more than doubled year-over-year to $37 million in Q3 2025, driven by a 108% increase in patients on therapy.
  • Xeris achieved net income for the first time in its history and reported adjusted EBITDA of $17.4 million for Q3 2025, with a gross margin of 85%.
  • The company is making strategic investments in commercial expansion for Recorlev and advancing its XP-8121 pipeline, with the phase three clinical trial expected to start in the second half of 2026, while committing to remain adjusted EBITDA positive.
Nov 6, 2025, 1:30 PM
Xeris Biopharma Holdings, Inc. Announces Record Q3 2025 Financial Results and Updates Full-Year Guidance
XERS
Earnings
Guidance Update
Revenue Acceleration/Inflection
  • Xeris Biopharma Holdings, Inc. reported record financial results for the third quarter ended September 30, 2025, with total product revenue increasing 40% year-over-year to $74 million.
  • Recorlev revenue notably grew 109% year-over-year to $37 million in Q3 2025, driven by increased patient demand.
  • The company achieved a net income of $0.6 million for Q3 2025, a significant improvement from a net loss of $15.7 million in the same period last year.
  • Xeris updated its full-year 2025 total revenue guidance to $285-$290 million, which implies 42% growth at the midpoint compared to last year.
Nov 6, 2025, 12:43 PM
Beta Bionics Reports Q3 2025 Financial Results and Raises Full Year Guidance
XERS
Earnings
Guidance Update
Revenue Acceleration/Inflection
  • Beta Bionics reported net sales of $27.3 million for the third quarter of 2025, representing a 63% increase compared to the third quarter of 2024.
  • The company's net loss for Q3 2025 was $14.2 million.
  • As of September 30, 2025, Beta Bionics had $274.0 million in cash, cash equivalents, short-term investments, and long-term investments.
  • Beta Bionics raised its full-year 2025 total revenue guidance to greater than $96.5 million (previously $88 million to $93 million) and its estimated gross margin to 54% to 55% (previously 52% to 55%).
Oct 28, 2025, 8:02 PM