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Catalio Capital Management, LP

CIK:0001958125
Asset Manager
$2B AUM
40 holdings
New York, NY, United States
Founded:2020
36 employees
Latest filing:Jun 30, 2025

Catalio Capital Management, LP is a New York-based investment firm founded in 2020. The firm specializes in the full lifecycle of innovative healthcare investing across private, public, and credit markets, supporting category-defining businesses in life sciences and biotechnology. Catalio is led by a team of managing partners, associates, and a board of advisors, with a network of renowned scientist-entrepreneurs as Venture Partners. The firm employs approximately 36 professionals and manages more than $1.7 billion in assets for institutional and sophisticated investors.

Investment Strategy

Catalio Capital Management invests in innovative healthcare companies at all stages and across the capital structure, including private equity, structured opportunities, and public equities. The firm leverages a proprietary network of scientist-entrepreneurs for rigorous scientific due diligence and aims to advise on disruptive trends in life sciences by providing early exposure to biomedical technologies. Catalio's investment approach is driven by deep scientific insight, a focus on emerging healthcare innovations, and the ability to generate value throughout companies' life cycles.

Top Buys
G
GILDGILEAD SCIENCES INC
+$25.2M
B
BSXBOSTON SCIENTIFIC CORP
+$24.6M
S
SLNOSOLENO THERAPEUTICS INC
+$22.8M
L
LLYELI LILLY & CO
+$22.5M
T
TEVATEVA PHARMACEUTICAL INDS LTD
+$19.6M
Top Sells
B
BDXBECTON DICKINSON & CO
-$46.7M
S
SWTXSPRINGWORKS THERAPEUTICS INC
-$33.5M
V
VCYTVERACYTE INC
-$22.6M
L
LIVNLIVANOVA PLC
-$15.0M
I
INSPINSPIRE MED SYS INC
-$13.7M

Top Holdings

L
LLYELI LILLY & CO
+8.8%$42.0M
B
BBIOBRIDGEBIO PHARMA INC
+8.4%$40.1M
S
SLNOSOLENO THERAPEUTICS INC
+7.2%$34.3M
A
ASNDASCENDIS PHARMA A/S
+6.5%$31.1M
I
ISRGINTUITIVE SURGICAL INC
+6.5%$30.8M

Equity Positions (39)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
L
LLY
ELI LILLY & CO8.81%$42.0M53,916$799.90$779.53+$22.5M
B
BBIO
BRIDGEBIO PHARMA INC8.40%$40.1M927,711$27.92$43.18+$6.8M
S
SLNO
SOLENO THERAPEUTICS INC7.20%$34.3M409,944$78.94$83.78+$22.8M
A
ASND
ASCENDIS PHARMA A/S6.51%$31.1M179,926$137.67$172.60+$581.0K
I
ISRG
INTUITIVE SURGICAL INC6.46%$30.8M56,674$529.60$543.41+$12.7M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+53.7%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+15.6%
ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES
+12.9%
ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS
+8.0%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+5.2%