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Avidity Partners Management LP

CIK:0001791827
Hedge Fund
$3B AUM
56 holdings
Dallas, TX, United States
Founded:2019
18 employees
Latest filing:Jun 30, 2025

Avidity Partners Management LP is an SEC-registered investment adviser headquartered in Dallas, Texas. Founded in 2019, the firm specializes in investment management, primarily serving institutional clients. As of early 2025, it manages billions in client assets with a team of approximately 18 employees, the majority of whom are investment professionals.

Investment Strategy

Avidity Partners Management LP focuses on long and short investments primarily in the healthcare sector, leveraging fundamental research to identify opportunities in public equities. The firm aims to generate strong risk-adjusted returns by concentrating on sectors with high growth potential, significant innovation, and dynamic regulatory environments, deploying capital with a bottom-up stock selection approach tailored to healthcare and related industries.

Latest 13F Filing Activity

Avidity Partners Management LP filed their most recent 13F report on Jun 30, 2025 disclosing 53 equity positions and 1 options positions with a total 13F market value of $502M. The fund increased holdings in Natera Inc., Hinge Health Inc., CG Oncology Inc. among other positions. Avidity Partners Management LP reduced exposure to Unitedhealth Group Inc., Regeneron Pharmaceuticals, Humana Inc. among others.

Top Buys
N
NTRANATERA INC
+$16.8M
H
HNGEHINGE HEALTH INC
+$16.7M
C
CGONCG ONCOLOGY INC
+$15.0M
I
ISRGINTUITIVE SURGIVAL INC
+$14.7M
G
GMABGENMAB A/S
+$13.4M
Top Sells
U
UNHUNITEDHEALTH GROUP INC
-$16.5M
R
REGNREGENERON PHARMACEUTICALS
-$16.1M
H
HUMHUMANA INC
-$14.7M
G
GKOSGLAUKOS CORP
-$13.2M
S
SNDXSYNDAX PHARMACEUTICALS INC
-$10.0M

Top Holdings

C
CGONCG ONCOLOGY INC
+7.8%$39.0M
B
BSXBOSTON SCIENTIFIC CORP
+6.9%$34.6M
N
NTRANATERA INC
+6.7%$33.7M
D
DNTHDIANTHUS THERAPEUTICS INC
+6.5%$32.5M
E
EXASEXACT SCIENCES CORP
+3.8%$18.9M

Equity Positions (53)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
CG ONCOLOGY INC7.77%$39.0M1,499,942$36.25$26.00+$15.0M
BOSTON SCIENTIFIC CORP6.89%$34.6M321,800$49.29$107.41+$668.9K
NATERA INC6.71%$33.7M199,300$99.88$168.94+$16.8M
DIANTHUS THERAPEUTICS INC6.47%$32.5M1,742,902$22.91$18.63+$1.3M
EXACT SCIENCES CORP3.76%$18.9M355,000$53.40$53.14+$3.6M

Options Positions (1)

TickerSecurityActionTypeNotional ValueContractsUnderlying PricePremium PaidChange (Contracts)Change (Value)
SYNDAX PHARMACEUTICALS INCSold
Call
$3.2M3,400$9.37$12.28-600-$1.7M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+52.1%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+16.0%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+4.6%
ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS
+4.1%
SERVICES-MEDICAL LABORATORIES
+3.5%