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Soleus Capital Management, L.P.

CIK:0001802630
Hedge Fund
$0 AUM
95 holdings
Greenwich, CT, US
Founded:2018
16 employees
Latest filing:Jun 30, 2025

Soleus Capital Management, L.P. is a Connecticut-based investment firm founded in 2018 that specializes in the healthcare sector, targeting innovative areas of life sciences such as biotech, medtech, diagnostics, and genomics. The firm invests across the healthcare lifecycle from developmental-stage companies to commercial enterprises, aiming to support the growth and commercialization of cutting-edge healthcare technologies. Soleus Capital employs approximately 16 people and serves both public and private companies seeking investment in complex and niche healthcare opportunities.

Investment Strategy

Soleus Capital seeks to generate superior risk-adjusted returns through idiosyncratic, catalyst-driven investing with a focus on complex and niche opportunities in the public and private healthcare space. Their strategy centers around identifying innovative life sciences businesses, including biotech, medtech, diagnostics, and genomics, and investing across the lifecycle from early development to commercial operations. The firm emphasizes supporting high-potential healthcare innovations through a combination of deep sector expertise and targeted capital deployment.

Top Buys
K
KRYSKRYSTAL BIOTECH INC
+$47.2M
A
ALNYALNYLAM PHARMACEUTICALS INC
+$34.8M
U
URGNUROGEN PHARMA LTD
+$29.9M
E
ELVELEVANCE HEALTH INC
+$27.2M
U
UNHUNITEDHEALTH GROUP INC
+$26.9M
Top Sells
T
TGTXTG THERAPEUTICS INC
-$31.5M
B
BMRNBIOMARIN PHARMACEUTICAL INC
-$26.7M
I
IOVAIOVANCE BIOTHERAPEUTICS INC
-$20.3M
M
MDGLMADRIGAL PHARMACEUTICALS INC
-$19.9M
H
HOLXHOLOGIC INC
-$18.7M

Top Holdings

K
KRYSKRYSTAL BIOTECH INC
+8.4%$126.9M
N
NVCRNOVOCURE LTD
+8.1%$122.9M
T
TGTXTG THERAPEUTICS INC
+5.3%$80.8M
U
UTHRUNITED THERAPEUTICS CORP DEL
+4.0%$60.3M
B
BBNXBETA BIONICS INC
+3.7%$55.6M

Equity Positions (94)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
K
KRYS
KRYSTAL BIOTECH INC8.40%$126.9M922,958$150.10$137.46+$47.2M
N
NVCR
NOVOCURE LTD8.14%$122.9M6,904,302$22.57$17.80+$24.5M
T
TGTX
TG THERAPEUTICS INC5.35%$80.8M2,243,935$16.51$35.99-$31.5M
U
UTHR
UNITED THERAPEUTICS CORP DEL3.99%$60.3M209,794$255.79$287.35+$12.4M
B
BBNX
BETA BIONICS INC3.68%$55.6M3,820,158$12.50$14.56+$14.1M

Options Positions (1)

TickerSecurityActionTypeNotional ValueContractsUnderlying PricePremium PaidChange (Contracts)Change (Value)
X
XBI
SPDR SERIES TRUSTNew
Put
$62.2M7,500$82.93$82.93+7,500+$62.2M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+45.2%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+18.1%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+16.5%
HOSPITAL & MEDICAL SERVICE PLANS
+4.9%
SERVICES-MEDICAL LABORATORIES
+3.9%