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Siobhan Mangini

Siobhan Mangini

Partner at VR Adviser, LLC

San Francisco, CA , United States

About

Siobhan Nolan Mangini is a Partner at Venrock, where she leads investments in healthcare technology and services. Based in San Francisco, she currently serves on the boards of Alight Solutions, Cityblock Health, SmithRx, Virta Health, and Marathon Health, helping to guide strategy and growth for pioneering companies in health benefits, care delivery, and digital health. Her focus at Venrock includes early and growth-stage healthcare companies transforming the delivery, access, and efficiency of care through technology-enabled models and data-driven solutions.

Prior to joining Venrock, Siobhan built her career as an operator at the intersection of healthcare, policy, and technology. She served as President and Chief Financial Officer at NGM Biopharmaceuticals and Castlight Health, and held prior board roles at Artemis Health. Her expertise spans scaling healthcare SaaS businesses, life sciences, health benefits innovation, and leveraging AI and advanced analytics in care delivery.

Siobhan holds an MBA from the Stanford Graduate School of Business, an MPA from Harvard Kennedy School, and a BS in Economics from the Wharton School of the University of Pennsylvania. She is recognized for her impact investing in healthcare technology and commitment to improving healthcare outcomes and affordability through strategic board leadership and operational excellence.

Career History

OrganizationRoleDate RangeDetails
VenrockPartnerMay 2025 to Present
Cityblock HealthMember Board of DirectorsFeb 2024 to Present
Audit Committee Chair
Alight SolutionsMember Board of DirectorsJan 2024 to Present
Audit Committee Chair / NYSE: ALIT
Virta HealthMember Board of DirectorsFeb 2023 to Present
SmithRxMember Board of DirectorsJan 2023 to Present
Marathon HealthMember Board of DirectorsAug 2021 to Present
Audit Committee Chair
Delflorien LabsFounderJan 2024 to May 2025
Partnering with founders and executive teams to build and scale transformational healthcare companies in computational biology, digital health, therapeutics, and value-based care. Supporting critical ...
January VenturesOperator NetworkJun 2018 to May 2025
January Ventures invests early and opens doors for the visionary founders of the future. We invest at the pre-seed and seed stage in the US and Europe. See our full portfolio and learn more at: januar...
NGM BiopharmaceuticalsPresident and Chief Financial OfficerJun 2022 to Dec 2023
Responsible for business development, strategy, product strategy, investor relations, communications, technology, real estate, people, finance and accounting. NASDAQ: NGM
NGM BiopharmaceuticalsChief Financial OfficerJul 2020 to Jun 2022
Artemis HealthMember Board of DirectorsFeb 2020 to Mar 2022
Acquired by Nomi Health

Education

Stanford University Graduate School of Business

MBA

Harvard Kennedy School

MPA

The Wharton School

BS Econ, Finance, Decision Processes

Skills & Expertise

Strategy
Cross-functional Team Leadership
Strategic Planning
Venture Capital
Corporate Development
Due Diligence
Private Equity
Business Strategy
Business Development
Start-ups
Finance
Portfolio Management
Financial Modeling
Investor Relations
Forecasting
Leadership
Executive Management
Cross-functional Team...
Start Ups
Marketing
Microsoft Office
Cross Functional Team Leadership
Sales

Others at VR Adviser, LLC (15)

NameRoleLocation
Bob Kocher
Bob Kocher
PartnerPalo Alto, CA , United States
Brian Ascher
Brian Ascher
PartnerMenlo Park, CA , United States
Ethan Batraski
Ethan Batraski
PartnerCA , United States
Ken Greenberg
Ken Greenberg
PartnerNew York, NY , United States
Lesley Kelly
Lesley Kelly
Head TraderNew York, NY , United States
L
Lisa Harris
PartnerRedmond, WA , United States
Mike Tyrrell
Mike Tyrrell
General PartnerCambridge, MA , United States
Nick Beim
Nick Beim
PartnerNew York, NY , United States
Andrew Gottesdiener
Andrew Gottesdiener
PartnerNew York, NY , United States
A
Anthony Evnin
partnerNew York, NY , United States
Showing 1-10 of 15 team members

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