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About
Siobhan Nolan Mangini is a Partner at Venrock, where she leads investments in healthcare technology and services. Based in San Francisco, she currently serves on the boards of Alight Solutions, Cityblock Health, SmithRx, Virta Health, and Marathon Health, helping to guide strategy and growth for pioneering companies in health benefits, care delivery, and digital health. Her focus at Venrock includes early and growth-stage healthcare companies transforming the delivery, access, and efficiency of care through technology-enabled models and data-driven solutions.
Prior to joining Venrock, Siobhan built her career as an operator at the intersection of healthcare, policy, and technology. She served as President and Chief Financial Officer at NGM Biopharmaceuticals and Castlight Health, and held prior board roles at Artemis Health. Her expertise spans scaling healthcare SaaS businesses, life sciences, health benefits innovation, and leveraging AI and advanced analytics in care delivery.
Siobhan holds an MBA from the Stanford Graduate School of Business, an MPA from Harvard Kennedy School, and a BS in Economics from the Wharton School of the University of Pennsylvania. She is recognized for her impact investing in healthcare technology and commitment to improving healthcare outcomes and affordability through strategic board leadership and operational excellence.
Career History
| Organization | Role | Date Range | Details |
|---|---|---|---|
| Venrock | Partner | May 2025 to Present | — |
| Cityblock Health | Member Board of Directors | Feb 2024 to Present | Audit Committee Chair |
| Alight Solutions | Member Board of Directors | Jan 2024 to Present | Audit Committee Chair / NYSE: ALIT |
| Virta Health | Member Board of Directors | Feb 2023 to Present | — |
| SmithRx | Member Board of Directors | Jan 2023 to Present | — |
| Marathon Health | Member Board of Directors | Aug 2021 to Present | Audit Committee Chair |
| Delflorien Labs | Founder | Jan 2024 to May 2025 | Partnering with founders and executive teams to build and scale transformational healthcare companies in computational biology, digital health, therapeutics, and value-based care. Supporting critical ... |
| January Ventures | Operator Network | Jun 2018 to May 2025 | January Ventures invests early and opens doors for the visionary founders of the future. We invest at the pre-seed and seed stage in the US and Europe. See our full portfolio and learn more at: januar... |
| NGM Biopharmaceuticals | President and Chief Financial Officer | Jun 2022 to Dec 2023 | Responsible for business development, strategy, product strategy, investor relations, communications, technology, real estate, people, finance and accounting. NASDAQ: NGM |
| NGM Biopharmaceuticals | Chief Financial Officer | Jul 2020 to Jun 2022 | — |
| Artemis Health | Member Board of Directors | Feb 2020 to Mar 2022 | Acquired by Nomi Health |
Education
Stanford University Graduate School of Business
MBA
Harvard Kennedy School
MPA
The Wharton School
BS Econ, Finance, Decision Processes
Skills & Expertise
Others at VR Adviser, LLC (15)
| Name | Role | Location |
|---|---|---|
| Partner | Palo Alto, CA , United States | |
| Partner | Menlo Park, CA , United States | |
| Partner | CA , United States | |
| Partner | New York, NY , United States | |
| Head Trader | New York, NY , United States | |
L Lisa Harris | Partner | Redmond, WA , United States |
| General Partner | Cambridge, MA , United States | |
| Partner | New York, NY , United States | |
| Partner | New York, NY , United States | |
A Anthony Evnin | partner | New York, NY , United States |
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