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VR Adviser, LLC
VR Adviser, LLC is an investment advisory firm based in New York, NY, and is affiliated with Venrock, a well-known venture capital and investment management platform. The firm was founded in 2014 and primarily serves pooled investment vehicles, focusing on long-term investment opportunities in small capitalization public companies. As of 2025, the firm manages several investment funds and employs 11 people, with all employees serving as investment professionals.
Investment Strategy
VR Adviser, LLC acts as an adviser to pooled investment vehicles with a core strategy of identifying long-term investment opportunities in small capitalization public companies, typically within the healthcare and life sciences sectors. The firm takes a research-driven approach, leveraging deep industry expertise to invest primarily in innovative and high-growth companies, often with a focus on the therapeutic development and biotechnology markets.
Latest 13F Filing Activity
VR Adviser, LLC filed their most recent 13F report on Jun 30, 2025 disclosing 31 equity positions with a total 13F market value of $1B. The fund increased holdings in Apogee Therapeutics Inc., Oric Pharmaceuticals Inc., Jade Biosciences Inc. among other positions. VR Adviser, LLC reduced exposure to Praxis Precision Medicines I, Dianthus Therapeutics Inc., Pharvaris N V among others.
Top Holdings
Equity Positions (31)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
A APGE | APOGEE THERAPEUTICS INC | 27.64% | $368.9M | 8,493,321 | $21.30 | $43.43 | +$51.6M |
O OCUL | OCULAR THERAPEUTIX INC | 8.88% | $118.4M | 12,762,462 | $6.11 | $9.28 | +$24.9M |
M MTSR | METSERA INC | 8.00% | $106.7M | 3,750,662 | $27.22 | $28.45 | +$4.6M |
E ELVN | ENLIVEN THERAPEUTICS INC | 6.05% | $80.8M | 4,026,331 | $19.61 | $20.06 | +$1.5M |
K KALV | KALVISTA PHARMACEUTICALS INC | 5.70% | $76.1M | 6,728,985 | $9.55 | $11.31 | -$1.3M |
Industry Allocation
Investment Team (16)
| Name | Role | Location | |
|---|---|---|---|
 | Partner | Palo Alto, CA , United States | |
 | Partner | Menlo Park, CA , United States | |
 | Partner | CA , United States | |
 | Partner | New York, NY , United States | |
 | Head Trader | New York, NY , United States | |
L Lisa Harris | Partner | Redmond, WA , United States | |
 | General Partner | Cambridge, MA , United States | |
 | Partner | New York, NY , United States | |
| Partner | New York, NY , United States | ||
A Anthony Evnin | partner | New York, NY , United States |
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