Sign in

Orbimed Advisors LLC

CIK:0001055951
Private Equity
$19B AUM
101 holdings
New York, NY, United States
Founded:1989
130 employees
Latest filing:Jun 30, 2025

OrbiMed Advisors LLC is a leading healthcare-focused investment firm headquartered in New York, NY, United States. Founded in 1989, OrbiMed invests across the spectrum of public and private healthcare companies globally, from early-stage startups to large multinational corporations, with a team of over 130 professionals. It is considered one of the world's largest dedicated healthcare investment firms and serves institutions, family offices, and other sophisticated investors.

Investment Strategy

OrbiMed's investment strategy focuses exclusively on the healthcare sector, including biopharmaceuticals, medical devices, diagnostics, digital health, and healthcare services. The firm seeks to invest globally in innovative companies at all stages, from seed and venture capital to growth equity and public companies. OrbiMed emphasizes supporting groundbreaking technologies addressing unmet medical needs and improving patient outcomes across diverse geographies, leveraging a global team of scientific, medical, and investment professionals.

Top Buys
C
CAICARIS LIFE SCIENCES INC
+$81.1M
S
SPRYARS PHARMACEUTICALS INC
+$40.4M
R
ROIVROIVANT SCIENCES LTD
+$31.3M
U
UPBUPSTREAM BIO INC
+$27.7M
S
SIONSIONNA THERAPEUTICS INC
+$25.5M
Top Sells
E
EWTXEDGEWISE THERAPEUTICS INC
-$127.0M
P
PFEPFIZER INC
-$97.6M
I
IONSIONIS PHARMACEUTICALS INC
-$76.6M
N
NBIXNEUROCRINE BIOSCIENCES INC
-$48.3M
T
TMOTHERMO FISHER SCIENTIFIC INC
-$45.3M

Top Holdings

S
SINXSINOVAC BIOTECH LTD
+8.4%$334.0M
B
BSXBOSTON SCIENTIFIC CORP
+7.6%$302.2M
L
LLYELI LILLY & CO
+6.6%$263.2M
E
EWTXEDGEWISE THERAPEUTICS INC
+5.1%$203.4M
E
ELVNENLIVEN THERAPEUTICS INC
+4.0%$159.7M

Equity Positions (94)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
S
SINX
SINOVAC BIOTECH LTD8.37%$334.0M2,718,735$0.00$0.00$0
B
BSX
BOSTON SCIENTIFIC CORP7.57%$302.2M2,813,200$26.13$107.41+$18.4M
L
LLY
ELI LILLY & CO6.59%$263.2M337,600$461.01$779.53-$15.7M
E
EWTX
EDGEWISE THERAPEUTICS INC5.10%$203.4M15,518,492$30.53$13.11-$127.0M
E
ELVN
ENLIVEN THERAPEUTICS INC4.00%$159.7M7,959,538$21.90$20.06+$3.0M

Options Positions (5)

TickerSecurityActionTypeNotional ValueContractsUnderlying PricePremium PaidChange (Contracts)Change (Value)
U
UNH
UNITEDHEALTH GROUP INCNew
Call
$15.6M500$311.97$311.97+500+$15.6M
A
AZN
ASTRAZENECA PLCNew
Call
$7.0M1,000$69.88$69.88+1,000+$7.0M
C
CGON
CG ONCOLOGY INCNew
Call
$3.9M1,500$26.00$26.00+1,500+$3.9M
A
APLS
APELLIS PHARMACEUTICALS INCNew
Call
$865.5K500$17.31$17.31+500+$865.5K
I
INMB
INMUNE BIO INCNew
Put
$115.5K500$2.31$2.31+500+$115.5K

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+50.3%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+13.2%
REFRIGERATION & SERVICE INDUSTRY MACHINERY
+8.4%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+8.2%
ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES
+7.3%