Jack Meehan

Kyle Mikson

Mason Carrico

Daniel Brennan

David Westenberg

Subhalaxmi Nambi

Tejas Savant

Tycho Peterson

Alex Aylen

Douglas Schenkel

Doug Schenkel

Eve Burstein

Harrison Parsons

Jake Allen

Luke Sergott

Madeline Mollman

Matthew Park

Salem Salem

Subbu Nambi

Sung Ji Nam

Tom Stevens

William Ruby

Yuko Oku

- PacBio announced innovations for its Revio and Vega platforms, featuring new SPRQ-Nx sequencing chemistry and consumables designed to **lower HiFi genome sequencing costs**.  **[1299130_ea08074fc7d347a68bca301879cf9419_0]** 
- These advancements are projected to reduce costs by as much as **40%** for customers operating at scale, bringing the price down to **less than $300 per genome**.  **[1299130_ea08074fc7d347a68bca301879cf9419_0]** 
- Beta testing for the SPRQ-Nx chemistry on the Revio platform is expected to commence in **November 2025**, with full commercial availability planned for **2026**.  **[1299130_ea08074fc7d347a68bca301879cf9419_0]** 
- The innovations also include new multiomic capabilities and features to support regulated research environments, with PacBio committing to long-term support for the Revio and Vega platforms through **2032**.  **[1299130_ea08074fc7d347a68bca301879cf9419_0]** **[1299130_ea08074fc7d347a68bca301879cf9419_1]**

PacBio Announces Innovations to Lower Genome Sequencing Costs and Expand Capabilities

- **PacBio's HiFi sequencing technology** has been selected as the primary platform for the **Korean Pangenome Reference Project**, a national initiative led by the Korea Disease Control and Prevention Agency (KDCA) and National Institute of Health (KNIH).  **[1299130_fa09661fd94a4d98b1d5d2a4133d49f9_0]** 
- The project aims to generate the first large-scale, telomere-to-telomere quality reference genomes for the Korean population and integrate this data into the global Human Pangenome Reference Consortium (HPRC).  **[1299130_fa09661fd94a4d98b1d5d2a4133d49f9_0]** 
- PacBio will provide an integrated sequencing solution, including **HiFi whole-genome sequencing**, Kinnex full-length RNA analysis, and CiFi technology, with a target of sequencing more than **1,000 whole genomes**.  **[1299130_fa09661fd94a4d98b1d5d2a4133d49f9_0]** 
- This initiative marks the **first national pangenome project to adopt PacBio's full technology suite**, combining accuracy, completeness, and resolution across DNA and RNA.  **[1299130_fa09661fd94a4d98b1d5d2a4133d49f9_1]**

PacBio HiFi Technology Selected for South Korea’s National Pangenome Project

- The **National Institute on Aging’s Long Life Family Study (LLFS)** selected **PacBio’s Revio systems** to generate comprehensive genomic and epigenomic data from as many as **7,800 participants**.  **[1299130_5772f1491fa54acc8edd2df009577d94_0]** 
- This collaboration aims to use PacBio's **HiFi long-read sequencing** to understand why longevity runs in families and what drives healthier aging.  **[1299130_5772f1491fa54acc8edd2df009577d94_0]** 
- The LLFS project was renewed by the National Institute on Aging for **$80 million** over **5 years** to perform this sequencing effort.  **[1299130_5772f1491fa54acc8edd2df009577d94_1]** 
- Sequencing is expected to commence in **Q4 2025** at the McDonnell Genome Institute at WashU Medicine, starting with an initial tranche of approximately **5,500 samples**.  **[1299130_5772f1491fa54acc8edd2df009577d94_1]**

PacBio's Technology Selected for National Institute on Aging's Longevity Study

PACIFIC BIOSCIENCES OF CALIFORNIA (PACB)