Joseph Altobello

Alexander Perry

Craig Kennison

James Hardiman

Noah Zatzkin

Tristan Thomas-Martin

Frederick Wightman

Robin Farley

Alice Wycklendt

Arthur Nagorny

Joseph Nolan

Megan Alexander

Megan Christine Alexander

Megan Claff

Sabahat Khan

Scott Stember

Sean Wagner

Stephen McGregor

- Encoded Therapeutics announced that the U.S. FDA granted **Regenerative Medicine Advanced Therapy (RMAT) designation** to **ETX101** for SCN1A+ Dravet syndrome, based on preliminary clinical evidence.  **[931015_9c4cc9f910d74536bd6a919ed5562e07_0]** 
- The company anticipates completing enrollment in its POLARIS dose-escalation clinical studies and presenting interim clinical efficacy data in **4Q25**.  **[931015_9c4cc9f910d74536bd6a919ed5562e07_0]** 
- Encoded's North Carolina **GMP manufacturing facility** is now fully operational and has initiated production of ETX101 to support pivotal trials expected in **1H26**.  **[931015_9c4cc9f910d74536bd6a919ed5562e07_0]** **[931015_9c4cc9f910d74536bd6a919ed5562e07_1]**

Encoded Therapeutics Receives FDA RMAT Designation for ETX101

Polaris (PII)