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AMGEN (AMGN)

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Earnings summaries and quarterly performance for AMGEN.

Research analysts who have asked questions during AMGEN earnings calls.

CS

Christopher Schott

JPMorgan Chase & Co.

6 questions for AMGN

Also covers: ABBV, AMRX, BIIB +15 more
Jay Olson

Jay Olson

Oppenheimer & Co. Inc.

6 questions for AMGN

Also covers: ACAD, BIIB, BNTX +22 more
Salveen Richter

Salveen Richter

Goldman Sachs

6 questions for AMGN

Also covers: ACAD, AGIO, ALLO +20 more
Terence Flynn

Terence Flynn

Morgan Stanley

6 questions for AMGN

Also covers: ABBV, ARVN, BIIB +17 more
YW

Yaron Werber

TD Cowen

6 questions for AMGN

Also covers: ALEC, ARGX, ASND +14 more
David Amsellem

David Amsellem

Piper Sandler Companies

5 questions for AMGN

Also covers: ABBV, ALKS, AMPH +27 more
ES

Evan Seigerman

BMO Capital Markets

5 questions for AMGN

Also covers: ABBV, ARVN, BIIB +15 more
Matthew Phipps

Matthew Phipps

William Blair

5 questions for AMGN

Also covers: ABBV, AGEN, ARGX +8 more
DR

David Risinger

Leerink Partners

4 questions for AMGN

Also covers: ABBV, BMY, HALO +9 more
AH

Alexandria Hammond

Wolfe Research

3 questions for AMGN

Also covers: ABBV, BMRN, BMY +6 more
CB

Courtney Breen

AllianceBernstein

3 questions for AMGN

Also covers: ABBV, BMY, GILD +4 more
Gregory Renza

Gregory Renza

RBC Capital Markets

3 questions for AMGN

Also covers: ACAD, ADCT, AGIO +12 more
Michael Yee

Michael Yee

Jefferies

3 questions for AMGN

Also covers: ALLO, BEAM, BIIB +14 more
UR

Umer Raffat

Evercore ISI

3 questions for AMGN

Also covers: ALKS, BHC, BIIB +15 more
CL

Carter L. Gould

Barclays

2 questions for AMGN

Also covers: ABBV, ALEC, BMY +7 more
Mohit Bansal

Mohit Bansal

Wells Fargo & Company

2 questions for AMGN

Also covers: ABBV, BMRN, BMY +16 more
CR

Christopher Raymond

Piper Sandler

1 question for AMGN

Also covers: ABBV, AGIO, ARDX +7 more
Conor MacKay

Conor MacKay

BMO Capital Markets

1 question for AMGN

Also covers: ABCL, ARVN, INCY
Geoff Meacham

Geoff Meacham

Citigroup Inc.

1 question for AMGN

Also covers: ABBV, BMY, GILD +8 more
JS

James Shin

Analyst

1 question for AMGN

Also covers: ABBV, AUTL, BMY +7 more
LI

Luca Issi

RBC Capital Markets

1 question for AMGN

Also covers: ADVM, ALLO, ALNY +12 more
Michael DiFiore

Michael DiFiore

Evercore ISI

1 question for AMGN

Also covers: AMLX, BIIB, ELAN +8 more
Mike DiFiore

Mike DiFiore

Evercore ISI

1 question for AMGN

Also covers: RPRX
OB

Olivia Brayer

Cantor

1 question for AMGN

Also covers: AUPH, BMRN, BMY +8 more
SR

Sadia Rahman

Wells Fargo

1 question for AMGN

Also covers: HALO, MLYS, TVTX
TA

Timothy Anderson

BofA Securities

1 question for AMGN

Also covers: ABBV, AZN, BIIB +10 more
TH

Trung Huynh

UBS Group AG

1 question for AMGN

Also covers: ABBV, ABOS, BMY +5 more

Recent press releases and 8-K filings for AMGN.

Amgen reports sustained 52-week weight loss for MariTide
AMGN
New Projects/Investments
  • 52-week extension data show patients who lost ≥15% body weight maintained reductions on lower or less frequent MariTide dosing in Phase 2 re-randomization.
  • No new safety signals observed during the second year, with low rates of nausea and vomiting.
  • MariTide’s novel antibody–peptide design activates GLP-1 and blocks GIP receptors, enabling monthly injections with potential for quarterly dosing as a competitive advantage.
  • Ongoing Phase 3 program includes a 72-week study to confirm durability, safety and optimal dosing schedules.
3 days ago
Amgen outlines 2026 growth drivers and pipeline progress
AMGN
  • Amgen identifies six core growth drivers in 2026 led by REPATHA, EVENITY and TEZSPIRE; REPATHA was annualizing at $3 billion at end-Q3 and grew 33%, while EVENITY grew >30% year-over-year.
  • MariTide program accelerated into six Phase III trials for obesity and related conditions; Phase II data show maintained weight loss with monthly/quarterly dosing and low GI adverse events, and a Phase III Type 2 diabetes program is set to begin.
  • Rare disease portfolio approached $5 billion in 2025, driven by UPLIZNA’s expanded approvals in NMOSD, IgG4-related disease and generalized myasthenia gravis with encouraging early uptake.
  • Biosimilars franchise delivered 42% year-over-year sales growth through first nine months of 2025, annualizing at $3 billion and contributing $13 billion since 2018.
  • Oncology bispecific T-cell engager pipeline advances: IMDELLTRA is standard of care in 2L+ small cell lung cancer, BLINCYTO remains SOC in B-ALL, and Xaluridomig is in two Phase III prostate cancer trials.
3 days ago
Amgen outlines growth strategy at 44th Annual J.P. Morgan Healthcare Conference
AMGN
Guidance Update
  • Broad and deep portfolio across four therapeutic areas—general medicine, oncology, rare disease, and inflammation—with multiple high-potential products and a robust Phase 3 pipeline
  • 10% YoY revenue growth and 14% YoY non-GAAP EPS growth in 2025, 6% dividend increase, five FDA approvals, initiation of six MariTide Phase 3 trials, Repatha VESALIUS-CV Phase 3 data showing 25% reduction in 3-point MACE, 42% biosimilars sales growth, and $6 billion debt reduction
  • Leading brands: Repatha (+33% Q3 YTD, annualizing at ~$3 B), EVENITY (+33% Q3 YTD, ~$2 B), and TEZSPIRE (+49% Q3 YTD, ~$1 B) driving volume-led growth through the decade
  • Oncology BITE platform and biosimilars fueling growth: IMDELLTRA up 33% QoQ (annualizing $0.5 B), BLINCYTO up 37% Q3 YTD ($1.5 B), and cumulative biosimilars sales of ~$13 B with 42% 9M 2025 growth
3 days ago
Amgen outlines 2026 growth strategy at J.P. Morgan Healthcare Conference
AMGN
  • 2025 performance: Revenues grew 10% and EPS grew 14% through nine months; biosimilars sales rose 42% and over $6 billion in debt was paid down.
  • 2026 growth drivers: Six core brands—Repatha ($3 billion annualized, 33% growth), Evenity (>30%), Tezspire—and portfolios in rare disease ($5 billion), innovative oncology, and biosimilars.
  • Late‐stage pipeline: Phase III trials include Olpazeran targeting Lp(a) for cardiovascular risk reduction, six studies of MariTide for obesity and type 2 diabetes with potential monthly/quarterly dosing, and Imdeltra moving into earlier lines of small cell lung cancer.
  • Capital allocation & BD: Will continue investing in internal/external innovation and manufacturing capacity; recent early-stage deals include a degrader collaboration with Dark Blue and antigen discovery with Disco.
3 days ago
Amgen outlines 2026 growth strategy at J.P. Morgan Healthcare Conference
AMGN
New Projects/Investments
  • In 2025, Amgen grew revenues by 10%, EPS by 14%, secured five FDA approvals, initiated six Phase 3 MariTide programs, and paid down $6 billion in debt.
  • For 2026, Amgen focuses on six growth drivers, led by core products Repatha, Evenity, and Tezspire, alongside its rare disease, oncology, and biosimilars portfolios.
  • Repatha annualized at $3 billion (+33% YoY), Evenity grew >30%, and Tezspire is expanding from severe asthma into chronic rhinosinusitis with nasal polyps, with COPD and EoE trials underway.
  • Key pipeline assets include Olpazeran (95–100% Lp(a) reduction; phase 3 CV outcomes), MariTide (monthly GLP-1 for obesity/T2D; six phase 3 trials), and bispecific T-cell engagers Imdeltra (SCLC) and Xaluridomig (prostate cancer).
  • Biosimilars have generated $13 billion of cumulative revenue since 2018 (42% growth in 2025), while early-stage collaborations with Dark Blue (degrader technology) and Disco (antigen discovery) highlight BD momentum.
3 days ago
Spyre Therapeutics outlines 2026 proof-of-concept milestones
AMGN
Guidance Update
Management Change
  • Spyre expects six proof-of-concept readouts in 2026 (three from SKYLINE UC trial and three from SKYWAY RA/PsA/axSpA trial), with SKYLINE Part A readouts starting in Q2.
  • SKYWAY basket trial enrollment for SPY072 across rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis is on track, with all readouts expected in 4Q 2026.
  • Kate Tansey Chevlen was appointed Chief Commercial Officer, bringing extensive immunology and inflammation marketing experience from Amgen.
  • As of September 30, 2025, pro forma cash, cash equivalents, and marketable securities totaled $783 million, supporting a cash runway into the second half of 2028.
4 days ago
DISCO Pharmaceuticals enters license agreement with Amgen
AMGN
New Projects/Investments
  • DISCO entered an exclusive license agreement with Amgen to advance novel cancer therapies targeting a surfaceome-identified cell surface protein using DISCO’s proprietary mapping platform.
  • Under the deal, DISCO is eligible for up to $618 million in potential milestone payments plus royalties, while Amgen secures exclusive global rights to develop and commercialize the resulting programs.
  • The collaboration leverages DISCO’s integration of cell-surface proteomics and protein community mapping to guide design of bispecific ADCs and T-cell engagers.
  • DISCO’s internal pipeline is focused on small cell lung cancer and microsatellite-stable colorectal cancer, with its first ADC programs nearing clinical entry.
Jan 7, 2026, 10:00 AM
Amgen acquires Dark Blue Therapeutics for $840 M
AMGN
M&A
  • Amgen agreed to acquire UK biotech Dark Blue Therapeutics for up to $840 million to add a preclinical small-molecule degrader targeting MLLT1/3 proteins implicated in AML.
  • Dark Blue’s lead AML candidate, DBT-13757, is in the final stages of preclinical development as a potentially first-in-class degrader of transcriptional regulators MLLT1/3.
  • Following the agreement, Dark Blue’s board resigned and Amgen will integrate the biotech into its existing R&D organization, including UK hubs.
  • The deal reinforces Amgen’s targeted protein degradation and leukemia research, coinciding with a ~25% share price rise over the prior 12 months.
Jan 6, 2026, 2:12 PM
Amgen acquires Dark Blue Therapeutics
AMGN
M&A
New Projects/Investments
  • Amgen agreed to acquire UK-based Dark Blue Therapeutics Ltd. in a deal valued at up to $840 million to bolster its oncology pipeline.
  • The deal adds an investigational small molecule degrader targeting MLLT1/3 proteins driving acute myeloid leukemia (AML), with promising preclinical efficacy.
  • Dark Blue Therapeutics will be integrated into Amgen’s early oncology research organization to advance clinical investigation of the AML program.
Jan 6, 2026, 2:00 PM
Amgen takes action with U.S. government to lower medicine costs
AMGN
New Projects/Investments
Product Launch
  • Amgen has agreed to implement the U.S. Administration’s Most Favored Nation pricing requests outlined in President Trump’s July 31 letter to lower medicine costs for American patients.
  • The company will expand its AmgenNow™ direct-to-patient program to include Aimovig® and Amjevita® at $299/month, about 60% and 80% discounts off current list prices, respectively; Repatha® was previously made available at $239/month in October 2025.
  • Since 2018, Amgen has invested over $40 billion in U.S. manufacturing and R&D; in 2025 alone it committed an additional $2.5 billion for facility expansions in Ohio and North Carolina and secured three years of tariff relief.
Dec 19, 2025, 7:23 PM