Earnings summaries and quarterly performance for AMGEN.
Executive leadership at AMGEN.
Robert A. Bradway
Chief Executive Officer and President
David M. Reese
Executive Vice President and Chief Technology Officer
James E. Bradner
Executive Vice President, Research and Development
Murdo Gordon
Executive Vice President, Global Commercial Operations
Peter H. Griffith
Executive Vice President and Chief Financial Officer
Board of directors at AMGEN.
Amy E. Miles
Director
Brian J. Druker
Director
Charles M. Holley, Jr.
Director
Ellen J. Kullman
Director
Greg C. Garland
Director
Mary E. Klotman
Director
Michael V. Drake
Director
Robert A. Eckert
Lead Independent Director
S. Omar Ishrak
Director
Tyler Jacks
Director
Wanda M. Austin
Director
Research analysts who have asked questions during AMGEN earnings calls.
Christopher Schott
JPMorgan Chase & Co.
6 questions for AMGN
Jay Olson
Oppenheimer & Co. Inc.
6 questions for AMGN
Salveen Richter
Goldman Sachs
6 questions for AMGN
Terence Flynn
Morgan Stanley
6 questions for AMGN
Yaron Werber
TD Cowen
6 questions for AMGN
David Amsellem
Piper Sandler Companies
5 questions for AMGN
Evan Seigerman
BMO Capital Markets
5 questions for AMGN
Matthew Phipps
William Blair
5 questions for AMGN
David Risinger
Leerink Partners
4 questions for AMGN
Alexandria Hammond
Wolfe Research
3 questions for AMGN
Courtney Breen
AllianceBernstein
3 questions for AMGN
Gregory Renza
RBC Capital Markets
3 questions for AMGN
Michael Yee
Jefferies
3 questions for AMGN
Umer Raffat
Evercore ISI
3 questions for AMGN
Carter L. Gould
Barclays
2 questions for AMGN
Mohit Bansal
Wells Fargo & Company
2 questions for AMGN
Christopher Raymond
Piper Sandler
1 question for AMGN
Conor MacKay
BMO Capital Markets
1 question for AMGN
Geoff Meacham
Citigroup Inc.
1 question for AMGN
James Shin
Analyst
1 question for AMGN
Luca Issi
RBC Capital Markets
1 question for AMGN
Michael DiFiore
Evercore ISI
1 question for AMGN
Mike DiFiore
Evercore ISI
1 question for AMGN
Olivia Brayer
Cantor
1 question for AMGN
Sadia Rahman
Wells Fargo
1 question for AMGN
Timothy Anderson
BofA Securities
1 question for AMGN
Trung Huynh
UBS Group AG
1 question for AMGN
Recent press releases and 8-K filings for AMGN.
- DISCO entered an exclusive license agreement with Amgen to advance novel cancer therapies targeting a surfaceome-identified cell surface protein using DISCO’s proprietary mapping platform.
- Under the deal, DISCO is eligible for up to $618 million in potential milestone payments plus royalties, while Amgen secures exclusive global rights to develop and commercialize the resulting programs.
- The collaboration leverages DISCO’s integration of cell-surface proteomics and protein community mapping to guide design of bispecific ADCs and T-cell engagers.
- DISCO’s internal pipeline is focused on small cell lung cancer and microsatellite-stable colorectal cancer, with its first ADC programs nearing clinical entry.
- Amgen agreed to acquire UK biotech Dark Blue Therapeutics for up to $840 million to add a preclinical small-molecule degrader targeting MLLT1/3 proteins implicated in AML.
- Dark Blue’s lead AML candidate, DBT-13757, is in the final stages of preclinical development as a potentially first-in-class degrader of transcriptional regulators MLLT1/3.
- Following the agreement, Dark Blue’s board resigned and Amgen will integrate the biotech into its existing R&D organization, including UK hubs.
- The deal reinforces Amgen’s targeted protein degradation and leukemia research, coinciding with a ~25% share price rise over the prior 12 months.
- Amgen agreed to acquire UK-based Dark Blue Therapeutics Ltd. in a deal valued at up to $840 million to bolster its oncology pipeline.
- The deal adds an investigational small molecule degrader targeting MLLT1/3 proteins driving acute myeloid leukemia (AML), with promising preclinical efficacy.
- Dark Blue Therapeutics will be integrated into Amgen’s early oncology research organization to advance clinical investigation of the AML program.
- Amgen has agreed to implement the U.S. Administration’s Most Favored Nation pricing requests outlined in President Trump’s July 31 letter to lower medicine costs for American patients.
- The company will expand its AmgenNow™ direct-to-patient program to include Aimovig® and Amjevita® at $299/month, about 60% and 80% discounts off current list prices, respectively; Repatha® was previously made available at $239/month in October 2025.
- Since 2018, Amgen has invested over $40 billion in U.S. manufacturing and R&D; in 2025 alone it committed an additional $2.5 billion for facility expansions in Ohio and North Carolina and secured three years of tariff relief.
- Global gene therapy market grew from US$7.21 billion in 2023 to US$8.85 billion in 2024 and is projected to reach US$36.55 billion by 2032 at a 19.4% CAGR.
- Growth driven by rising demand for curative and precision-based therapies, with about 19 new gene therapy launches expected between 2026 and 2032.
- High development and pricing barriers, with gene therapy development costs up to US$5 billion and therapies like Pfizer’s Beqvez (~US$3.5 million) and Lenmeldy (~US$4.25 million) facing reimbursement challenges.
- Viral vectors were the largest segment in 2023, neurology led therapeutics, and North America remained the largest regional market.
- Strategic initiatives include Amgen’s US$1 billion manufacturing expansion, while the competitive landscape is led by Biogen, Novartis, Alnylam, Sarepta, and others.
- FDA approved UPLIZNA® (inebilizumab-cdon) for generalized myasthenia gravis in adults positive for anti-AChR and anti-MuSK antibodies, the first CD19-targeted B-cell therapy in this indication.
- The regimen consists of two loading doses followed by two annual maintenance infusions, compared with dosing intervals of 2–8 weeks for competing treatments.
- Approval leverages UPLIZNA’s established safety and efficacy in neuromyelitis optica spectrum disorder and IgG4-related disease, broadening Amgen’s autoimmune neuromuscular portfolio.
- The FDA approved UPLIZNA (inebilizumab-cdon) for adults with generalized myasthenia gravis who are anti-AChR and anti-MuSK antibody positive, with twice-yearly maintenance dosing after two loading doses.
- UPLIZNA is the first and only CD19-targeted B cell therapy approved for gMG, depleting pathogenic B cells underlying disease pathology.
- In the Phase 3 MINT trial, UPLIZNA achieved a -4.2 vs -2.2 mean change in MG-ADL score at Week 26 (p<0.0001) and sustained benefit through Week 52 in AChR+ patients.
- This approval represents UPLIZNA’s third FDA indication, following its approval for NMOSD in June 2020 and for IgG4-RD in April 2025.
- Closed a $70 million Series A financing co-led by 5AM Ventures and OrbiMed, with participation from Monograph Capital, to advance ultra-long-acting obesity and metabolic candidates.
- Appointed Chris Boulton, former Vice President and Global Marketing Therapy Area Head for Obesity at Amgen, as Chief Executive Officer to drive commercialization.
- Syndicate investors Kush Parmar (5AM Ventures), Peter Thompson (OrbiMed), and Fred Cohen (Monograph Capital) joined the board alongside independent director David Martin.
- Platform engineered for once-monthly and once-quarterly dosing of peptide therapeutics to improve adherence and tolerability in obesity treatment.
- Amgen delivered 10% revenue growth through 9M 2025 (12% in Q3) driven by 11% product sales growth and 14% volume growth, reflecting its volume-focused strategy.
- The in-market portfolio features six key growth drivers: Repatha & Evenity +30% YTD, Tezspire +50%, rare disease (~ $5 bn annualized, +12%), innovative oncology +11%, and biosimilars +40% (~ $3 bn annualized).
- Pipeline advances include six Phase 3 Maritide studies (obesity/diabetes) with Phase 2 maintenance data expected in early 2026, Olpaceran Phase 3 Lp(a) trial (~ 7,300 pts), and multiple Imdeltra Phase 3 small-cell lung cancer studies.
- Capital allocation emphasizes mid-20s % R&D spending growth, ~$200 mn of Q3 business development, $2.2–2.3 bn capex on U.S. manufacturing expansions, and a wide BD aperture focused on innovation.
- Engaging with the U.S. administration on pricing policy, launched Amgen Now (Repatha at $2.39/mo direct-to-consumer), and managing Prolia/Xgeva biosimilar erosion alongside Evenity growth.
- Amgen delivered 10% revenue growth through the first nine months of FY 2025, including 11% product sales growth driven by 14% volume growth, and in Q3 reported 12% revenue growth on 14% volume growth.
- The in-line portfolio’s six major growth drivers posted YTD gains of Repatha +30%, Evenity +30%, TESSPIRE +50% (now $1 B in U.S. sales), rare disease +12% (annualizing near $5 B), innovative oncology +11%, and biosimilars +40%.
- Innovation remains top priority with non-GAAP R&D up 31% in Q3 and a mid-20% R&D spend target for FY 2025; key programs include six global Phase III studies for Meritide, Phase III for opaciran, and bispecific T-cell engager trials in small cell lung and prostate cancers.
- Capital allocation focuses on internal/external innovation: $2.2–2.3 B CapEx guide, $200 M of business development in Q3, ongoing debt reduction post-Horizon, and a wide BD pipeline with high standards.
- Amgen continues productive policy engagement, launched Amgen Now direct-to-consumer Repatha at $2.39/month via GoodRx, and is exploring expanded access models for future products.
Quarterly earnings call transcripts for AMGEN.
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