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AMGEN (AMGN)

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Research analysts who have asked questions during AMGEN earnings calls.

Salveen Richter

Salveen Richter

Goldman Sachs

8 questions for AMGN

Also covers: ACAD, AGIO, ALLO +21 more
Terence Flynn

Terence Flynn

Morgan Stanley

8 questions for AMGN

Also covers: ABBV, ARVN, BIIB +17 more
YW

Yaron Werber

TD Cowen

8 questions for AMGN

Also covers: ALEC, ARGX, ASND +15 more
David Amsellem

David Amsellem

Piper Sandler Companies

7 questions for AMGN

Also covers: ABBV, ALKS, AMPH +28 more
CS

Christopher Schott

JPMorgan Chase & Co.

6 questions for AMGN

Also covers: ABBV, AMRX, BIIB +15 more
Jay Olson

Jay Olson

Oppenheimer & Co. Inc.

6 questions for AMGN

Also covers: ACAD, BIIB, BNTX +24 more
CB

Courtney Breen

AllianceBernstein

5 questions for AMGN

Also covers: ABBV, BMY, GILD +4 more
ES

Evan Seigerman

BMO Capital Markets

5 questions for AMGN

Also covers: ABBV, ARVN, BIIB +15 more
Matthew Phipps

Matthew Phipps

William Blair

5 questions for AMGN

Also covers: ABBV, AGEN, ARGX +8 more
UR

Umer Raffat

Evercore ISI

5 questions for AMGN

Also covers: ALKS, BHC, BIIB +15 more
DR

David Risinger

Leerink Partners

4 questions for AMGN

Also covers: ABBV, BMY, HALO +10 more
Michael Yee

Michael Yee

Jefferies

4 questions for AMGN

Also covers: ABBV, ALLO, BEAM +19 more
Mohit Bansal

Mohit Bansal

Wells Fargo & Company

4 questions for AMGN

Also covers: ABBV, BMRN, BMY +16 more
AH

Alexandria Hammond

Wolfe Research

3 questions for AMGN

Also covers: ABBV, BIIB, BMRN +7 more
Gregory Renza

Gregory Renza

RBC Capital Markets

3 questions for AMGN

Also covers: ACAD, ADCT, AGIO +12 more
AH

Alex Hammond

Sidoti & Company, LLC

2 questions for AMGN

Also covers: BIIB, BMRN, CBUS +4 more
CL

Carter L. Gould

Barclays

2 questions for AMGN

Also covers: ABBV, ALEC, BMY +8 more
CS

Chris Schott

JPMorgan Chase & Company

2 questions for AMGN

Also covers: ABBV, AMRX, BIIB +11 more
LC

Louise Chen

Cantor Fitzgerald

2 questions for AMGN

Also covers: ARDX, CNTB, GILD +18 more
CR

Christopher Raymond

Piper Sandler

1 question for AMGN

Also covers: ABBV, AGIO, ARDX +7 more
Conor MacKay

Conor MacKay

BMO Capital Markets

1 question for AMGN

Also covers: ABCL, ARVN, INCY +1 more
Geoff Meacham

Geoff Meacham

Citigroup Inc.

1 question for AMGN

Also covers: ABBV, AMLX, BMY +12 more
JS

James Shin

Analyst

1 question for AMGN

Also covers: ABBV, AUTL, BMY +7 more
LI

Luca Issi

RBC Capital Markets

1 question for AMGN

Also covers: ADVM, ALLO, ALNY +13 more
Michael DiFiore

Michael DiFiore

Evercore ISI

1 question for AMGN

Also covers: ALT, AMLX, BIIB +11 more
MG

Michael Gee

UBS Financial Services Inc.

1 question for AMGN

Mike DiFiore

Mike DiFiore

Evercore ISI

1 question for AMGN

Also covers: RPRX
OB

Olivia Brayer

Cantor

1 question for AMGN

Also covers: AUPH, BMRN, BMY +9 more
SR

Sadia Rahman

Wells Fargo

1 question for AMGN

Also covers: HALO, MLYS, TVTX
TA

Timothy Anderson

BofA Securities

1 question for AMGN

Also covers: ABBV, AZN, BIIB +10 more
TH

Trung Huynh

UBS Group AG

1 question for AMGN

Also covers: ABBV, ABOS, BMY +5 more

Recent press releases and 8-K filings for AMGN.

Amgen reports 2025 growth and 2026 outlook at Leerink Global Healthcare Conference
AMGN
Guidance Update
M&A
  • Amgen closed 2025 with 13 products delivering double-digit growth, 14 products exceeding $1 billion in annual sales, and 18 records, driving double-digit revenue and EPS growth. Key drivers included Repatha, Evenity, Tezspire (each +30%+), a $5 billion rare-disease portfolio (+14%), and a $3 billion biosimilars portfolio (+37%) in 2025.
  • The 2026 pipeline features six global phase III studies, led by MariTide (monthly to quarterly dosing for obesity/diabetes), the Olpasiran OCEAN(a) outcome study (timing delayed), and two phase III Sjögren’s studies of Dazodalibep (completion expected H2 2026).
  • Expect a typical Q1 seasonal headwind from U.S. insurance cycles, lower Otezla/IMRALDI sales, €282 million of 2025 European Otezla sales facing generic entry, Prolia/XGEVA biosimilar erosion, and $250 million of Q4 2025 inventory build; Q1 non-GAAP operating margin guided at ~43%, lowest in the year.
  • Having restored its balance sheet post-Horizon integration, Amgen maintains disciplined inorganic strategy—prioritizing best innovation, cash-on-cash returns, existing research synergies, and rapid integration.
1 day ago
Amgen outlines 2026 growth drivers at Leerink Conference
AMGN
Guidance Update
New Projects/Investments
M&A
  • Amgen closed 2025 with broad momentum: 13 products achieved double-digit growth, 14 exceeded $1 billion in annual sales, its rare disease portfolio reached $5 billion (+14% y-o-y), and flagship franchises Repatha, Evenity, and Tezspire each grew >30% y-o-y【1】.
  • For Q1 2026, Amgen anticipates typical seasonal headwinds—including U.S. insurance cycle impacts, Otezla facing EU generic entry (2025 EU sales €282 million), ongoing Prolia/XGEVA biosimilar erosion, and a $250 million inventory build—and expects non-GAAP operating margin near 43% (Q4 2025 level)【2】.
  • The 2026 pipeline features 6 global Phase 3 studies of MariTide across weight management, Type 2 diabetes, obstructive sleep apnea, heart failure, and ASCVD (with data readouts into next year); an event-driven OCEAN(a) trial of Olpasiran has been delayed; and two Phase 3 trials of dazodalibep in Sjögren’s disease complete in H2 2026【1】【2】.
  • Having restored its committed leverage post-Horizon deal, Amgen remains structurally agnostic on M&A, prioritizing best-in-class innovation, accretive cash returns, existing research alignment, and rapid integration in any inorganic transaction【9】.
1 day ago
Amgen details 2026 growth drivers and outlook at Leerink
AMGN
Guidance Update
New Projects/Investments
M&A
  • Amgen closed 2025 with strong momentum: 13 products delivered double-digit growth, 14 products exceeded $1 billion in annual sales, and 18 products achieved record performance, supporting double-digit revenue and EPS growth in 2025.
  • The company’s six key growth drivers are Repatha, Evenity, Tezspire, its rare disease portfolio ($5 billion in 2025 sales, +14%), innovative oncology BiTE platforms (e.g., IMDELLTRA, Xaluritamig), and biosimilars ($3 billion in 2025 sales, +37%).
  • A robust Phase III pipeline includes MariTide (monthly to quarterly dosing for obesity and type 2 diabetes), the OCEAN(a) olpasiran cardiovascular outcome study, and two Phase III trials of dazodalibep in Sjögren’s disease (completion expected H2 2026).
  • Amgen anticipates seasonal Q1 2026 headwinds from the US insurance cycle, lower Q1 sales for Otezla/Imraldi, accelerated erosion of Prolia/XGEVA, and a $250 million Q4 2025 inventory build, with non-GAAP operating margin around 43% in Q1 2026.
  • With its balance sheet restored post-Horizon integration, Amgen remains open to M&A, licensing, and partnerships, focusing on innovation value, cash returns, research synergies, and rapid integration.
1 day ago
Amgen declares Q2 2026 dividend
AMGN
Dividends
  • On March 4, 2026, Amgen’s Board declared a $2.52 per share dividend for the second quarter of 2026.
  • The dividend will be paid on June 5, 2026.
  • Shareholders of record as of May 15, 2026 will receive the dividend.
8 days ago
Amgen highlights 2025 momentum and 2026 outlook at TD Cowen Healthcare Conference
AMGN
  • 2025 performance: 13 products with double-digit growth, 14 exceeding $1 billion in annual sales and 18 record performers, driving double-digit revenue and EPS growth.
  • Key growth drivers in 2025: Repatha, EVENITY and TEZSPIRE each grew > 30% yoy; rare disease portfolio delivered $5 billion (+14%; UPLIZNA +73%); biosimilars generated $3 billion (+37%).
  • 2026 Q1 headwinds: seasonal U.S. insurance cycle, Otezla EU generic entry (€282 million sales in 2025), Prolia/Xgeva biosimilar erosion and prior quarter inventory build; non-GAAP operating margin ~43%.
  • Commercial initiative: Repatha AmgenNow direct-to-patient program at $239/month, with > 5,000 patients enrolled, alongside preferred formulary placement and reduced copays (< $50/month).
  • Pipeline focus: MariTide (monthly dosing for obesity/diabetes), olpasiran Lp(a) OCEAN(a) outcome study progressing, dazodalibep Sjögren’s phase III readout expected H2 2026.
Mar 2, 2026, 6:10 PM
Amgen outlines 2025 performance and 2026 growth drivers at TD Cowen conference
AMGN
  • 2025 performance summary: 13 products delivered double-digit growth, 14 exceeded $1 billion in annual sales, and 18 produced record performance, driving double-digit revenue and EPS growth in 2025.
  • Six key growth drivers delivered momentum: Repatha, EVENITY, and TEZSPIRE each grew over 30% and became multi-billion dollar franchises; the rare disease portfolio reached $5 billion (+14%); biosimilars generated $3 billion (+37%).
  • Pipeline highlights include MariTide’s potential for monthly or less frequent obesity dosing, the OCEAN(a) olpasiran outcome study progressing with a later completion date, and fully enrolled phase III trials of dazodalibep in Sjögren’s disease set to complete in H2 2026.
  • Q1 headwinds expected from U.S. insurance benefit cycles, higher co-pays, European Otezla generic entry ($282 million 2025 sales), biosimilar erosion of Prolia/Xgeva, and a $250 million inventory build in Q4 2025; Q1 non-GAAP operating margin forecast to mirror Q4 2025 at ~43%.
Mar 2, 2026, 6:10 PM
Amgen highlights strong 2025 growth and updates Q1 outlook at TD Cowen Conference
AMGN
Guidance Update
Product Launch
  • Exited 2025 with broad momentum: 13 products delivered double-digit growth, 14 exceeded $1 billion in annual sales, and 18 achieved record performance, driving double-digit revenue and EPS growth.
  • Q1 2026 expected to face seasonal U.S. insurance headwinds, lower Otezla/Enbrel sales, European generic entry for Otezla (€282 million 2025 sales) and accelerated Prolia/Xgeva erosion; non-GAAP operating margin guided at ~43%.
  • Repatha access expanded: now preferred on virtually all U.S. formularies, average copay < $50/month, over 50% of Medicare patients with no prior authorization, plus AmgenNow direct-to-patient program at $239/month with > 5,000 enrolled.
  • Uplizna uptake in IgG4-related disease: ~500 unique prescribers treating a 35,000-patient market across all therapy lines; myasthenia gravis launch split 50% bio-naive/bio-experienced prescriptions.
  • Pipeline focus on differentiated assets: MariTide for obesity with monthly dosing, multiple phase II/III studies underway; olpasiran’s event-driven OCEAN(a) trial delayed; dazodalibep Sjögren’s phase III readouts expected H2 2026.
Mar 2, 2026, 6:10 PM
Amgen issues $4 billion of senior notes due 2031–2056
AMGN
Debt Issuance
  • On February 17, 2026, Amgen sold four tranches of senior unsecured notes totaling $4.0 billion, comprising $1.0 billion of 4.200% notes due 2031, $1.75 billion of 4.850% notes due 2036, $0.5 billion of 5.500% notes due 2046 and $0.75 billion of 5.650% notes due 2056, generating net proceeds of approximately $3.961495 billion.
  • The notes pay interest semi-annually in arrears each February 19 and August 19, rank pari passu with all existing and future senior unsecured debt and are effectively subordinated to any secured obligations of Amgen’s subsidiaries.
  • Holders have an optional put on a change-of-control event at 101% of principal plus accrued interest, and the company may optionally redeem notes at a make-whole premium prior to specified call dates.
Feb 19, 2026, 9:27 PM
Amgen outlines oncology R&D priorities and pipeline updates at Citi Summit
AMGN
New Projects/Investments
  • Amgen reaffirmed its oncology R&D framework to focus on transformative therapies in both hard-to-treat solid tumors and hematologic malignancies, anchored by its T-cell engager (BiTE) and precision small-molecule platforms.
  • IMDELLTRA (DLL3 BiTE) has full U.S. approval in second-line small cell lung cancer, is administered at over 1,600 U.S. sites, and is being evaluated in three additional Phase 3 trials (first-line metastatic, maintenance and limited stage), plus subcutaneous and extended-interval dosing studies to improve access.
  • BLINCYTO’s development includes a subcutaneous formulation and earlier-line B-ALL trials (e.g., Golden Gate in patients ≥55 years), with Phase II studies underway in SLE and refractory rheumatoid arthritis, aiming to enhance convenience and expand indications.
  • Xaluritamig (STEAP1 BiTE) is advancing in Phase III for post-taxane and pre-taxane metastatic castration-resistant prostate cancer—designed to demonstrate overall survival benefit versus chemotherapy without requiring biomarker gating—and is also being explored in Ewing sarcoma.
Feb 18, 2026, 8:15 PM
Amgen outlines oncology R&D priorities and pipeline updates at Citi summit
AMGN
New Projects/Investments
  • Amgen reaffirmed its R&D framework targeting differentiated, transformative therapies across hard-to-treat solid tumors and select hematologic malignancies, with two core modalities—T-cell engagers and precision small molecules—and selective ADC investments leveraging its biologics and chemistry strengths.
  • The DLL3-targeting BiTE IMDELLTRA received full approval in second-line or later small cell lung cancer, now administered at over 1,600 U.S. sites (mostly community); three pivotal phase III trials in first-line metastatic, maintenance and limited-stage settings are ongoing globally.
  • KRAS G12C inhibitor LUMAKRAS is approved in second-line NSCLC and third-line colorectal cancer; ongoing studies include CodeBreaK 202 (chemotherapy ± LUMAKRAS vs. chemo + pembrolizumab in first-line NSCLC) and a first-line CRC trial of LUMAKRAS + Vectibix + FOLFIRI, which showed ~55% ORR and >90% DCR in phase II.
  • STEAP1-targeting BiTE xaluritamig is being advanced in prostate cancer with survival-driven pivotal trials both pre- and post-taxane (chemo-free in the former) and in relapsed/refractory Ewing sarcoma, aiming to fill unmet need without biomarker gating.
Feb 18, 2026, 8:15 PM